Search Results - cancer+diagnostics

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Brain Cancer: Novel Prognostic Method and Therapeutic Target for Glioblastoma
Advantages: A precision-guided method for identifying glioblastoma-related genes that improves assessment of the current prognostic biomarker Enables the identification of potential novel therapeutic targets: GLP1R agonists, which are already used for managing obesity and type 2 diabetes, could be explored as treatments for GBM Broader Applications:...
Published: 3/24/2025   |   Inventor(s): George Blanck, Teresa Thomas
Keywords(s): Cancer Diagnostics, Medical Diagnostics, Oncology, Therapeutics
Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Oncology, Technology Classifications > Medical > Therapeutics
Sensitive and Robust Biosensing Using Plasmonic Enhancement of Fluorescence by Rapid Thermal Annealed Silver Nanostructures
­Advantages: Enhances cancer biomarker sensitivity Scalable production methods Enables low-concentration detection Ideal for portable diagnostics Summary: In cancer diagnostics, a major challenge is the detection of biomarkers at extremely low concentrations, particularly at the nanogram per milliliter (ng/ml) level, which is crucial for...
Published: 9/17/2024   |   Inventor(s): Shuangming Li, Venkat Bhethanabotla
Keywords(s): Biomarker, Cancer Diagnostics
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Electronics > Nanotechnology, Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Medical > Medical Nanotechnology, Technology Classifications > Medical > Medical Diagnostics
Cancer Patients with an Anti-Epstein-Barr Virus (EBV) Immune Response Show Improved Outcomes
­Advantages: Cancers with an adaptive immune response (T cell and antibody response) to EBV correlate with better outcomes: tested in ovarian cancer, stomach adenocarcinoma, Burkitt lymphoma, and diffused large B cell lymphoma Could be developed into a potential predictive biomarker that utilizes antibody and/or T cell receptor CDR3 sequencing...
Published: 11/7/2024   |   Inventor(s): George Blanck, Rahul Jain, Taha Huda, Srijit Paul, Boris Chobrutskiy, Andrea Chobrutskiy, Nandini Goel, Madeline Baker, Joanna Song, Veda Vangala, Michael Diaz
Keywords(s): Cancer Diagnostics
Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Medical > Medical Diagnostics
Novel Method of Cancer Diagnosis by Multifractality of Surface Potential
­Advantages: Enhanced diagnostic accuracy for precise cancer cell identification. Complementary insights from both morphology and surface potential analysis. Label-free and minimally invasive, ensuring safety and sample integrity. Background: Breast and ovarian are the most frequent types of cancer among women worldwide. Morbidity and mortality...
Published: 4/10/2025   |   Inventor(s): Dmitri Voronin, Phat Huynh, Dang Nguyen, Grace Binder, Sharad Ambardar, Trung Le
Keywords(s): Cancer Diagnostics, Medical Imaging
Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Medical > Medical Imaging
Novel Method of Cancer Diagnosis by Label-Free Spectroscopic Imaging of Cell Membrane
­Advantages Utilizing rough aluminum substrates reduces expenses compared to traditional noble metals in cancer diagnostics. Our method ensures safety by using biocompatible aluminum substrates, eliminating the toxicity of noble metals. Atomic force microscopy (AFM) enhances precision, providing reliable Raman signal calibration for accurate...
Published: 3/5/2024   |   Inventor(s): Dmitri Voronine, Phat Huynh, Dang Nguyen, Grace Binder, Sharad Ambardar
Keywords(s): Biomarker, Cancer Diagnostics, Spectroscopy
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Electronics > Spectroscopy
Novel Peptidomimetics for the treatment of Doxorubicin-Induced Cardiomyopathy
­Advantages: Compounds (peptidomimetic inhibitors) that prevent Doxorubicin-induced cardiomyopathy (DIC) that can occur with cancer chemotherapy Peptide therapeutics have high specificity, potency, and low toxicity when compared to traditional small molecule drugs Potentially enabling cancer patients to receive DOX treatment without compromising...
Published: 1/14/2025   |   Inventor(s): Xueling Ma
Keywords(s): Biotechnology, Cancer Diagnostics, Cancer Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Oncology
Novel target to treat the growth of uterine leiomyomas
Advantages: Our investigators have identified restricted patterns of CD73 expression that broadly implicate extracellular adenosine as a key mediator for the growth of uterine leiomyomas. Targeting activity at Type2B adenosine receptors could be potentially used as a strategy to shrink leiomyomas while avoiding potential limitation and systemic...
Published: 9/3/2024   |   Inventor(s): Matthew Anderson, Xiaofang Guo, Umit Kayisli
Keywords(s): Cancer Diagnostics, Cancer Treatment, Women’s Health
Category(s): Technology Classifications > Cancer > Cancer Diagnostics
SHIP-1 Regulation of Tumoricidal Myeloid Cells in Pancreatic Cancer
Advantages: Proposes a method that aids in the therapeutic intervention of Pancreatic Ductal Adenocarcinoma Administering therapeutic agents, such as apigenin, potentially improves anti-tumor responses Method of monitoring helps track the progression and regression of the disease Summary: Pancreatic Ductal Adenocarcinoma (PDAC) is one of the...
Published: 2/1/2024   |   Inventor(s): Tomar Ghansah
Keywords(s): Cancer Diagnostics, Cancer Treatment, Medical Diagnostics, Therapeutics
Category(s): Technology Classifications > Cancer
AI: Real Data-Driven Analytical Predictive Model For Pancreatic Cancer, Survival Monitoring Indicator, Survival Methodologies
­Competitive Advantages: The inventive model identifies the risk factors, and interaction and predicts the survival time of a pancreatic cancer patient. The analytic survival indicator can be used to evaluate the effectiveness of different treatments given to patients, by identifying if the survival time of the patients is increasing,...
Published: 7/17/2023   |   Inventor(s): Chris Tsokos, Aditya Chakraborty
Keywords(s): Artificial Intelligence, Cancer, Cancer Diagnostics, Drug Treatment Evaluation, Medical Diagnostics
Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Cancer > Cancer Treatment Adenocarcinomas, Technology Classifications > Medical > Oncology
Natriuretic Peptide Receptor as a Biomarker for Cancer
Our inventors have come up with a diagnostic method for differentiating low grade cancers from high grade cancers by correlating the level of NPRA to favorable or unfavorable prognosis. With this method, clinical detection of a number of malignancies, amongst included are various cancers, can be diagnosed and treated earlier improving the chances for...
Published: 8/27/2023   |   Inventor(s): Shyam Mohapatra, Subhra Mohapatra
Keywords(s): Cancer Diagnostics
Category(s): Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Cancer
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