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Search Results - george+blanck
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Cancer Patients with an Anti-Epstein-Barr Virus (EBV) Immune Response Show Improved Outcomes
Advantages: Cancers with an adaptive immune response (T cell and antibody response) to EBV correlate with better outcomes: tested in ovarian cancer, stomach adenocarcinoma, Burkitt lymphoma, and diffused large B cell lymphoma Could be developed into a potential predictive biomarker that utilizes antibody and/or T cell receptor CDR3 sequencing...
Published: 8/29/2024
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Inventor(s):
George Blanck
,
Rahul Jain
,
Taha Huda
,
Srijit Paul
,
Boris Chobrutskiy
,
Andrea Chobrutskiy
,
Nandini Goel
,
Madeline Baker
,
Joanna Song
,
Veda Vangala
,
Michael Diaz
Keywords(s):
Cancer Diagnostics
Category(s):
Technology Classifications > Cancer > Cancer Diagnostics
,
Technology Classifications > Medical > Medical Diagnostics
Immunogenomics Parameters for Patient Stratification in Alzheimer’s Disease
Advantages The study employs a novel approach by characterizing T-cell receptor (TCR) recombination reads and using a chemical complementarity assessment for the complementarity determining regions (CDR3s) of the TCRs and candidate antigens. By investigating the role of TCR CDR3s and their interactions with Tau protein, the research sheds light...
Published: 9/26/2023
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Inventor(s):
Taha Huda
,
George Blanck
Keywords(s):
Biomarker
,
Medical Diagnostics
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Medical > Neuroscience
Tau as a Biomarker for Low Grade Glioma (LLG) and Neuroblastoma Patients
Competitive Advantages A prognostic biomarker for LGG and neuroblastoma May be used to develop new treatments May increase patient survivability Summary The association of the MAPT gene (microtubule-associated protein Tau), which encodes Tau protein, with various tauopathies and other neurological disorders has long been established. However,...
Published: 9/9/2024
|
Inventor(s):
George Blanck
,
Saif Zaman
,
Boris Chobrutskiy
Keywords(s):
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Medical > Oncology
Immune Receptor Mutant Peptide Complementarity Scoring for Therapy Design and Prognosis
Competitive Advantages A prognostic genomic-based method Improved survival prediction accuracies Improved immunotherapy effectiveness predictions Measures tumor immune activity Summary USF researchers have developed a genomics-based method to provide prognoses based on tumor immune activity. Also provided are indications for components for...
Published: 9/30/2022
|
Inventor(s):
George Blanck
,
Boris Chobrutskiy
Keywords(s):
Category(s):
Technology Classifications > Cancer > Cancer Diagnostics
,
Technology Classifications > Cancer