Search Results - xin+wei+wang

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C41 Analogs
This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024   |   Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics
Applications of Deuterated Aldehydes and Isonitriles
This innovation is a novel method of synthesizing calcium channel blockers, with applications to extend the half-life of heart disease medications. This can be used as building blocks to create new pharmaceuticals or potentially used to expand the lifespan of current medications. It has applications to site specific calcium-channel blocking that can...
Published: 6/7/2024   |   Inventor(s): Christopher Hulme, Wei Wang, Kevin Schofield, Yueteng Zhang
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
New Deuterated Amino Acid Derivatives
Compositions and methods of making involve the use of alternative acids as reactants instead of carboxylic acids, which produce deuterated amino acids, while carboxylic acids can only synthesize alkyl amino acids. Introducing deuterium to amino acids and derivatives improves biologically active compounds and therapeutics. Modification improves properties...
Published: 6/6/2024   |   Inventor(s): Wei Wang, Yue Dong
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Materials > Biomaterials, Technology Classifications > Life Sciences
Bioorthogonal Activation of PROTAC Prodrugs
Utilizing proteolysis targeting chimeras (PROTACs) to degrade proteins that are important for tumorigenesis has become a potential therapeutic strategy for cancer. This innovation is an on-demand prodrug strategy called click-release proteolysis targeting chimeras, or “crPROTACs.” The crPROTACs strategy utilizes bioorthogonal chemistry and...
Published: 1/16/2024   |   Inventor(s): Wei Wang, Mengyang Chang, Giri Gnawali
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
A Broad Spectrum Antimicrobial that Synergizes with Copper
University of Arizona researchers have developed an invention that synergizes with copper to kill and prevent further growth of a broad spectrum of pathogens (i.e both Streptococcus pneumoniae and Valley Fever with the potential to work on other pathogens). This therapy does not allow for resistance to be built by the microbes. Published paper with...
Published: 1/5/2024   |   Inventor(s): Michael Johnson, Joseph Alvin, Angela Rivera, Wei Wang
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics
Aluminum Oxide Thin Films from Aqueous Precursors
A patented aqueous synthesis route for making high quality alumina thin films of exceptional quality and smoothness Background Aluminum oxide has many desirable properties making it technologically important as a barrier coating, optical film, and as a dieletric thin-film component of electronic devices. The quality of the material varies with...
Published: 6/17/2024   |   Inventor(s): Douglas Keszler, Wei Wang
Keywords(s):  
Category(s): Engineering
A Viral Exposure Signature to Define and Detect Early Onset Hepatocellular Carcinoma
Abstract: Early detection of liver cancer, such as hepatocellular carcinoma (HCC), is key to improve cancer-related mortality. More than 800,000 people are diagnosed with this cancer each year throughout the world. Liver cancer is also a leading cause of cancer deaths worldwide, accounting for more than 700,000 deaths each year. Currently, millions...
Published: 4/8/2024   |   Inventor(s): Xin Wei Wang, Jinping Liu, Wei Tang
Keywords(s): Biomarker, HCC, hepatocellular carcinoma, Liver cancer, viral infection, Wang
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Diagnostics
Gene Signature for Predicting Solid Tumors Patient Prognosis
Abstract: HCC is the most frequent malignant tumor in the liver and the third leading cause of cancer death worldwide.  A progressive sequence of somatic mutations and epigenetic changes of oncogenes or tumor suppressor genes are believed to cause tumor development. However, high genomic instability in tumors causes the accumulation of genomic aberrations...
Published: 4/8/2024   |   Inventor(s): Xin Wei Wang, Stephanie Roessler
Keywords(s): Biomarker, driver gene, gene signature, HCC, hepatocellular carcinoma, prognostic
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology
A Gene-Based Prognostic for Hepatocellular Carcinoma Patient Response to Adjuvant Transcatheter Arterial Chemoembolization
Abstract: Hepatocellular Carcinoma (HCC) is one of the most common cancers worldwide with largely unfavorable outcomes due to a lack of effective treatment options for patients in the later state of disease. The gold standard of care for HCC patients with intermediate to locally advanced tumors is transcatheter arterial chemoembolization (TACE), a procedure...
Published: 4/8/2024   |   Inventor(s): Xin Wei Wang, Valerie Miller
Keywords(s): Gene-Expression Signature, hepatocellular carcinoma, Patient Stratification, prognostic
Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Reconfigurable RF/Digital Hybrid 3D Interconnect
­A novel interconnect technology that enables system designers to take better advantage of increased IC power while satisfying energy consumption and space limitations. Background: As the semiconductor industry develops technologies on the nano-scale, interconnect latency is increasing. This places serious limitations on designs, as the input/output...
Published: 2/23/2024   |   Inventor(s): Robert Geer, Wei Wang, Tong Jing
Keywords(s): Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents
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