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Monitoring Structural Health Using Diffractive Optical Processors (Case No. 2025-201)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel structural health monitoring system that is highly accurate and cost effective, addressing limitations in current infrastructure and civil health monitoring and a rise in public safety concerns. Background: The need for structural health monitoring...
Published: 12/5/2025   |   Inventor(s): Aydogan Ozcan, Ertugrul Taciroglu, Yuntian Wang, Yuhang Li
Keywords(s): 3D structures, Adaptive Optics, AI-generated images and content, all-optical diffractive computing, all-optical transformation, analog computing, analog optical computing, Analogue Electronics, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial-intelligent materials, civil engineering, civil infrastructure, civil monitoring, computational imaging, computational imaging task, Construction, deep diffractive network, Diffraction, diffractive design, diffractive image reconstruction, diffractive network, diffractive processor, diffractive surface, digital image reconstruction, electromagnetic spectrum, Electro-Optics, Image Analysis, Image Processing, Image Resolution, image restoration, image signal processing, Imaging, Infrastructure, Lens (Optics), linear optics, Nanostructure, optical processor, optically-guided structural monitoring, Optics, passive light-matter interactions, security imaging, Signal Reconstruction, Structural health monitoring, structural health monitoring (SHM), structure monitoring, Structures
Category(s): Electrical, Electrical > Signal Processing, Electrical > Imaging, Materials, Materials > Construction Materials, Electrical > Visual Computing, Electrical > Computing Hardware, Electrical > Instrumentation, Energy & Environment, Energy & Environment > Energy Efficiency, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Software & Algorithms > Programs
Aerodynamics-Informed Design Optimization of Vehicles with Machine Learning (Case No. 2025-083)
Intro Sentence: UCLA researchers from the Department of Mechanical and Aerospace Engineering have developed a machine-learning–guided aerodynamic optimization framework that accelerates the design of electric vehicles by coupling high-fidelity simulations with data-driven shape prediction. Background: Electric vehicle (EV) technologies have...
Published: 11/5/2025   |   Inventor(s): Kunihiko Taira, Jonathan Tran, Kai Fukami, Daisuke Umehara, Kenta Inada, Yoshimichi Ono, Kenta Ogawa
Keywords(s):  
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Materials, Materials > Functional Materials, Energy & Environment
Prototype Software for Neuron-Centric Memory Architecture in AI (Case Nos. 2025-327/328)
Summary: Researchers at UCLA’s Department of Integrative Biology & Physiology and Neurobiology have pioneered the first prototype of a novel, neuron-centric AI architecture featuring intracellular memory and adaptive computation capabilities, designed to enhance deep learning performance and efficiency. Background: Deep learning leverages...
Published: 12/10/2025   |   Inventor(s): Alain Glanzman, David Glanzman
Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial intelligence-generated content, Artificial Neural Network, Artificial Neural Network Artificial Neuron, artificial-intelligent materials, generative artificial intelligence, Medical artificial intelligence (AI), Neuron, neurons, Software, Software & Algorithms, Software Development Tools, Software-enabled learning
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical, Electrical > Computing Hardware
Design of Task-Specific Optical Systems Using Broadband Diffractive Neural Networks (Case No. 2020-174)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a diffractive neural network that can process an all-optical, 3D printed neural network for deep learning applications. Background: Deep learning, a method of machine learning that mimics the human brain’s connectivity through a series of “neural...
Published: 10/17/2025   |   Inventor(s): Aydogan Ozcan, Yi Luo, Deniz Mengu, Yair Rivenson
Keywords(s):  
Category(s): Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing
Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)
Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...
Published: 10/1/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun
Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery
Optical Generative Models (Case No. 2025-067)
Summary: Researchers in the UCLA Department of Electrical and Computer Engineering have developed an optics-based system to rapidly generate synthetic images. Background: Generative AI models that create synthetic images, human-like natural language processing capabilities, and even new protein designs are critical for a diverse array of applications....
Published: 11/17/2025   |   Inventor(s): Aydogan Ozcan, Shiqi Chen
Keywords(s): Adaptive Optics, all-optical diffractive computing, Electro-Optics, Optical Coherence , Optical computing, Optical Generative Models, Optics
Category(s): Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Optics & Photonics, Electrical, Electrical > Signal Processing, Electrical > Imaging, Electrical > Visual Computing
A Nanoengineered Immunosensor to Detect Multiple Circulating Biomarkers for Rapid Prediction of Acute Thrombosis (UCLA Case No. 2025-015)
UCLA researchers in the Department of Cardiology have developed a nanoengineered immune sensor that uses machine learning to detect multiple circulating biomarkers for rapid, accurate prediction of acute thrombosis. BACKGROUND: Acute thrombosis represents a significant contributor to both acute and chronic illnesses. Moreover, the correlation between...
Published: 11/25/2025   |   Inventor(s): Tzung Hsiai
Keywords(s):  
Category(s): Materials > Nanotechnology, Platforms > Diagnostic Platform Technologies, Therapeutics > Cardiovascular, Diagnostic Markers > Targets And Assays, Medical Devices > Monitoring And Recording Systems, Software & Algorithms > Artificial Intelligence & Machine Learning
Automated Detection of Lung Nodules in Medical Images (Case No. 2012-512)
Summary UCLA researchers have developed an automated image processing system that segments lung regions in CT scans, identifies candidate high-intensity structures (like nodules), and classifies lung nodules (including solid and ground glass) using geometric analysis. The system aims to reduce false positives while maintaining high sensitivity in lung...
Published: 9/23/2025   |   Inventor(s): Matthew Brown
Keywords(s):  
Category(s): Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Medical Devices, Medical Devices > Hospital Systems, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems
Method and Apparatus for Segmentation of Dense MR Images Using Deep Learning with Domain Adaptation (Case No. 2025-208)
Summary: UCLA researchers from the Department of Radiological Sciences have developed a deep learning-based segmentation framework that enables fully automated and reproducible analysis of left ventricular (LV) function in Displacement Encoding with Stimulated Echoes (DENSE) MRI. Background: Myocardial strain is a key metric for analyzing how much...
Published: 10/17/2025   |   Inventor(s): Xiaodong Zhong, Siyue Li, Kim-Lien Nguyen
Keywords(s): acute myocardial infarction, adjustable mount, aneurysm drainage, automatic leveling, bedside decisions, blood pressure monitoring, cardiac cycle, Cardiac Electrophysiology, Cardiac failure, Cardiac Magnetic Resonance Imaging, Cardiac MRI, Cardiovascular, Cardiovascular Disease, Cardiovascular Disease Nephropathy, cardiovascular diseases, cardiovascular monitoring, cerebrospinal fluid (CSF) drainage, Cine MRI, clamp, critical-care, CSF drainage, Deep learning MRI, DENSE MRI, laser alignment, Left ventricular segmentation, lumbar drains, Motion analysis, MRI, multiparametric MRI (mpMRI), Myocardial strain, non-invasive cardiac monitoring, operator variability, passive reflective target, phlebostatic axis measurement, Pseudo-labeling, radial MRI, Segment Anything Model (SAM), self-leveling system, transducer alignment, Unsupervised domain adaptation (UDA)
Category(s): Medical Devices > Cardiac, Electrical > Imaging, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Therapeutics > Cardiovascular, Therapeutics > Radiology, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging
Methods and Systems for Low-Cost Medical Image Annotation Using Non-experts (Case No. 2025-108)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an AI-based interface designed to enable individuals without specialized training to identify arthritis in medical imaging. Background: The use of artificial intelligence (AI) for medical imaging analysis holds great promise for the future of healthcare....
Published: 11/6/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang
Keywords(s): 3D tissue imaging, AI-guided diagnostics, AI-guided medical imaging, AI-guided medical intervention, arthritis, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, Artificial Neural Network, bioimaging, Computer-Aided Diagnosis, computer-aided radiology, Diagnostic Markers & Platforms, Diagnostic Test, diagnostics, generative artificial intelligence, Image Analysis, Image Resolution, Imaging, infrared thermal imaging, Machine Learning, machine learning modeling, machine perception, Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Pathology, Medical artificial intelligence (AI), Medical diagnostics, Medical Imaging, Microscopy And Imaging, non-invasive imaging, osteoarthritis, radial MRI, radiologic imaging, Radiology, Radiology / Radiomitigation, radiosurgery
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Musculoskeletal Disease, Therapeutics > Radiology
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