Search Results - rheumatoid+arthritis

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Interleukin 24 (IL-24) to treat inflammatory diseases
Abstract: Proinflammatory T-helper 17 cells (Th17) play important roles in host immune defense against infection, but uncontrolled activation of these cells, known as the Th17 response, may cause autoimmune and autoinflammatory diseases (uveitis, multiple sclerosis, rheumatoid arthritis, and Crohn’s disease) through the effects of Th17 lineage...
Published: 4/8/2024   |   Inventor(s): Rachel Caspi, Mary Mattapallil, Reiko Yamane, Wai Po Chong
Keywords(s): Caspi, Crohn’s disease, IL-24, inflammatory disease, interleukin 24, Multiple sclerosis, National Eye Institute, NEI, proinflammatory T-helper 17 cell, RHEUMATOID ARTHRITIS, Th17, uveitis
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology
Glucocorticoid-induced TNFR Family-Related Receptor Ligand (GITRL) Antibodies for Diagnosis and Treatment of Immune System Disorders
This technology provides novel antibodies and methods for diagnostics and treatment of disorders arising from dysregulation of the immune system using antibodies directed against glucocorticoid-induced tumor necrosis factor receptor family-related receptor ligand (GITRL). Also available are hybridomas producing anti-mouse GITRL monoclonal antibodies...
Published: 10/28/2024   |   Inventor(s): Ethan Shevach
Keywords(s): antibodies, AUTOIMMUNE DISEASE, CD25, CD4, GITR, GITRL, IB3XXX, IBXXXX, IDXXXX, immune response, immune suppressor, IXXXXX, Multiple sclerosis, Patent Category - Biotechnology, RHEUMATOID ARTHRITIS, T cell, Treg
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics, Application > Therapeutics
Osteoanabolism by 14-3-3zeta
Project ID: D2021-48 Background Bone loss is one of the common symptoms associated with normal aging and pathologies. An increased bone mass loss and mineral density are the primary reason for osteoporosis, arthritis, fractures, etc. Together it affects millions of individuals in the US alone. While several drugs targeting the prevention of bone...
Published: 6/18/2024   |   Inventor(s): Ritu Chakravarti, Saurabh Chattopadhyay
Keywords(s): 14-3-3z, 14-3-3 zeta, Arthritis, Autoimmune, Osteoarthritis, Rheumatoid Arthritis
Category(s): Inflammation & Immunity, Long Bone/Joint Repair