Search Results - musculoskeletal

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Occupational Safety: Portable Exposure Assessment System for Prevention of Musculoskeletal Injury
CDC researchers have developed the Portable Exposure Assessment System (PEAS), a field-based, remotely deployed tool to monitor and provide early warning of working conditions that have a high likelihood of musculoskeletal injury. PEAS is a noninvasive, real-time, instrument-based system. Sensor technology simultaneously measures and collects data...
Published: 10/28/2024   |   Inventor(s): Bryan Wimer, Shengke Zeng, Christopher Pan
Keywords(s): AA1XXX, AA4XXX, AAXXXX, AE1BXX, AE1CXX, AE1XXX, AE2AXX, AE2BXX, AE2XXX, AE3XXX, AE4XXX, AEXXXX, AFXXXX, AG3XXX, AGXXXX, apparatus, ASSESSING, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Conditions, Injured, Injuries, INJURY, LEAD, Likely, lumbar, Method, MOBILE, MOBILES, MUSCLE, Muscles, MUSCULAR, musculoskeletal, NIOSH, NIOSH-DSR, Occupational health, PERSONAL, Personalized, Portable, SAFE, Safely, SAFETY, System, VMXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, WORKER, WORKER safety, WORKERS, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YAXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Neurology, Application > Research Materials, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, ResearchProducts > Computational models/software, Application > Non-Medical Devices, Application > Occupational Safety and Health, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Oncology
ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to study...
Published: 10/28/2024   |   Inventor(s): Erwin Van Meir
Keywords(s): Animal Model, COVID19, Microbiology/Infectious Diseases, Musculoskeletal, Neuroscience/Pain, Oncology
Category(s): TechPub Algolia > Research Tools
Surgical Device for Eyelid Ptosis Correction
ApplicationSurgical device to perform clamping, incision, and closure for correcting eyelid ptosis.Key BenefitsSimplifies the Müller muscle resection that decreases surgical procedure time.Eliminates the risk of cutting sutures that cause dehiscence and improves the final appearance.Market SummaryPtosis (drooping upper eyelids) is a common condition...
Published: 12/4/2024   |   Inventor(s): Denise Kim, Jacquelyn Borinski, Andrew Kolpitcke, Mohamad Ali Naja, Drew Padilla
Keywords(s): Hospital and Surgery, Musculoskeletal, Sensory Organs/Ophthalmology
Category(s): TechPub Algolia > Medical Device
Knock-In Mouse Model of Oculopharyngeal Muscular Dystrophy
ApplicationConditional knock-in mouse mimicking Oculopharyngeal muscular dystrophy.Technical SummaryOculopharyngeal muscular dystrophy (OPMD) is rare genetic disease caused by a mutation in the PABPN1 gene. In this mutation, the number of GCG trinucleotide repeats at the 5' end of PABPN1 are increased, which leads to an expansion of an alanine repeat...
Published: 10/28/2024   |   Inventor(s): Grace Pavlath, Anita Corbett, Katherine Vest
Keywords(s): Animal Model, Musculoskeletal, Sensory Organs/Ophthalmology
Category(s): TechPub Algolia > Research Tools
Small Molecule Therapeutic for Regeneration of Cartilage
ApplicationSmall molecule therapeutic that can be delivered locally to enhance TGF-beta activity and promote cartilage growth.Key BenefitsIncreases production of protease inhibitors, simultaneously stimulating production and blocking degradation of extracellular matrix (ECM). Potentially reduces or eliminates need for joint replacements by regenerating...
Published: 12/4/2024   |   Inventor(s): Scott Boden, Sreedhara Sangadala
Keywords(s): Musculoskeletal, Regenerative Medicine, Small Molecule
Category(s): TechPub Algolia > Therapeutics
Nematode Model of Nemaline Myopathy
Application An invertebrate animal model of nemaline myopathy using Caenorhabditis elegans. Key Benefits C. elegans with pathological mutations of tropomyosin that cause nemaline myopathy. Technical Summary Nemaline myopathy, or rod myopathy, is a congenital and hereditary neuromuscular disorder that causes muscle weakness of varying severity....
Published: 11/20/2024   |   Inventor(s): Shoichiro Ono
Keywords(s): Animal Model, Musculoskeletal, Neuroscience/Pain
Category(s): TechPub Algolia > Research Tools
Methods For Determining The Presence Or Risk Of Developing Facioscapulohumeral Dystrophy (FSHD)
ApplicationsThis technology provides a DNA-based diagnostic method to determine the presence or the susceptibility of developing Facioscapulohumeral Dystrophy (FSHD) and also a method to treat FSHD.AdvantagesCurrently, the diagnostic test for FSHD1 requires pulse-field gel electrophoresis and Southern blotting to detect the contraction of the D4Z4 repeats,...
Published: 5/7/2024   |   Inventor(s): Al-Rabi Tawil, Stephen Tapscott, Linda Geng, Silvere Van Der Maarel, Lauren Snider, Richard Lemmers
Keywords(s): Diagnostic, Musculoskeletal
Category(s): Diagnostic
HSA LR Mice (Mouse Model of Myotonic Dystrophy)
ApplicationsThe invention offers a transgenic mouse model for myotonic dystrophy. This mouse model expresses expanded CUG repeats and develops myotonia and myopathy. This model can be utilized to examine interactions between the loss- and gain-of-function effects of the mutation and to investigate the mechanism for nuclear retention and toxicity of...
Published: 10/28/2024   |   Inventor(s): Charles Thornton
Keywords(s): Disease Model, Mouse, Musculoskeletal, Research Tool
Category(s): Research Tools
Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues
The invention provides methods for the protection, repair and regeneration of articular cartilage, and fibrocartilaginous tissues using recombinant parathyroid hormones, such the FDA approved biologic agent – teriparatide (Forteo®, Eli Lilly).Problem Solved by this TechnologyCurrently, the only treatments for cartilage degeneration and osteoarthritis...
Published: 5/7/2024   |   Inventor(s): Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'keefe, Hani Awad
Keywords(s): Arthritis, Musculoskeletal, Orthopaedics
Category(s): Therapeutic