Search Results - blanka+sharma

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Bioactive Nanoparticles for an Osteoarthritis Therapeutic
Neutralizes Reactive Oxygen Species to Reduce Oxidative Stress in Osteoarthritic TissueThese nanoparticles break down the reactive oxygen species (ROS) generated during joint trauma and inflammation, thereby mitigating oxidative stress in order to treat or prevent osteoarthritis (OA) as well as other inflammatory diseases. Oxidative stress plays a central...
Published: 6/27/2021   |   Inventor(s): Blanka Sharma, Isaac Adjei, Shreedevi Kumar
Keywords(s): Maganese Disorder, MNO2, Nanoparticle, osteoarthritis, Oxidative stress, PEG, Poly ethylene glycol, Reactive Oxygen Species, ROS
Category(s): Technology Classifications > Human Health Care > Therapeutics
Therapeutic Nanoparticles for Non-Viral Drug Delivery to Natural Killer Cells
Transfects Natural Killer Cells Without the Use of VirusesThese nanoparticles enable the delivery of nucleic acids or drugs to immunosuppressed natural killer (NK) cells to restore their cytotoxic functions in tumor microenvironments. Globally, cancer causes one of every six deaths, with the number of new cases expected to rise to 23.6 million per year...
Published: 6/27/2021   |   Inventor(s): Blanka Sharma, Isaac Adjei
Keywords(s): Drug Delivery, Immunotherapy, MNO2, Nanoparticle, Natural Killer Cells, nucleic acid delivery
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Drug Delivery
Drug Delivery Nanoparticles That Improve Efficacy of Drugs for Osteoarthritis
Adheres to Cartilage Surface to Sustain Drug Localization for Better Therapeutic EffectThese biodegradable drug nanocarriers adhere to the extracellular matrix of cartilage, improving drug efficacy in joints during surgery or arthroscopy for those with osteoarthritis. Osteoarthritis (OA) is a disease characterized by the degeneration of cartilage in...
Published: 6/27/2021   |   Inventor(s): Blanka Sharma, Shannon Brown
Keywords(s): arthtritis, cartilage targeting, drug retention, drug targeting, intra-articular, Nanoparticle, Nanotechnology
Category(s): Technology Classifications > Human Health Care > Drug Delivery