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Search Results - t-cell+activation
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SELECTIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES
SELECTIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a novel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
Reece Akana
Keywords(s):
Cancer
,
Immuno-Oncology
,
T-Cell Activation
Category(s):
Technology Classifications > Biology
Synthetic Viscoelastic Activating Cells (SynVACs) for T cell engineering (UCLA Case No. 2023-190)
UCLA researchers in the Department of Bioengineering have developed a novel microfluidic device that produces synthetic viscoelastic cells for efficacious therapeutic T cell activation. BACKGROUND: T cell-based therapies, such as the chimeric antigen receptor (CAR) T cell therapy, represents a significant advancement in cancer treatment, particularly...
Published: 7/19/2024
|
Inventor(s):
Zeyang Liu
,
Song Li
,
Lili Yang
,
Yan-Ruide Li
Keywords(s):
CAR-T cell therapy
,
Synthetic antigen presenting cells (SynVACs)
,
T Cell
,
T cell based therapy
,
T-cell activation
,
T-cell engineering
,
t-cells
Category(s):
Therapeutics > Oncology
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner. Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023
|
Inventor(s):
Michael Fischbach
,
Kazuki Nagashima
,
Yiyin Chen
,
Djenet Bousbaine
Keywords(s):
Autoimmune
,
Bacteria
,
T-Cell Activation
Category(s):
Technology Classifications > Biology
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner. Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023
|
Inventor(s):
Michael Fischbach
,
Kazuki Nagashima
,
Yiyin Chen
Keywords(s):
Autoimmune
,
Bacteria
,
T-Cell Activation
Category(s):
Technology Classifications > Biology
HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS
HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS Researchers at Stanford have developed a technology that uses biomechanical force to initiate T-cell triggering in a high throughput method, facilitating the exploration of the force- and sequence-dependent landscape of T-cell responses. Adaptive immunity...
Published: 3/17/2023
|
Inventor(s):
Xiang Zhao
,
Adam White
,
Polly Fordyce
,
Yinnian Feng
,
K Garcia
Keywords(s):
Catch Bond
,
High-Throughput Mechanobiology
,
Ligand Discrimination
,
Mechanotransduction
,
Single-Cell Microfluidics
,
Spectrally Encoded Beads
,
T-Cell Activation
,
T-Cell Biophysics
,
T-Cell Receptor
Category(s):
Technology Classifications > Biology