Search Results - sidi+bencherif

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Injectable, Bioadhesive Cryogel Scaffolds for Biomedical Uses
INV-19031 Background In the US, over 27 million hospital visits include invasive, therapeutic surgeries. However, despite substantial advances in gelatin, fibrin, and cyanoacrylate-based biomaterial adhesives, a robust solution with tissue integration, biomechanical integration, and wet-tissue adhesion remains a significant challenge. Hydrogels and...
Published: 9/10/2024   |   Inventor(s): Devyesh Rana, Sidi Bencherif, Nasim Annabi
Keywords(s):  
Category(s): Technology Classifications > 1. Life Science > Therapeutics, Chemistry, Technology Classifications > 1. Life Science > Drug Delivery
Oxygen as an immunological adjuvant or co-adjuvant to reinforce vaccines and immunotherapies
INV-21019 Background Vaccines are crucial to fight infections, cancer, and autoimmune conditions as they aid in generating immune response before the onset of the disease. Vaccines developed with purified molecules often do not stimulate an effective immune response as compared to the immune response generated against natural infection. Hence, adjuvants...
Published: 9/10/2024   |   Inventor(s): Sidi Bencherif, Thibault Colombani
Keywords(s): Adjuvant, Biomaterials, Co-adjuvant, Oxygen, Vaccines
Category(s): -Pharmaceutical Composition, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery
Biomaterial-based COVID-19 vaccine
INV-20110 Background To date, there are over 16 million confirmed cases of people infected with the COVID-19 virus, with over 649,000 deaths worldwide. While the medical community works to develop a way to combat this virus, there are currently no known effective treatments or vaccines. A number of RNA vaccines are currently in development. The...
Published: 9/10/2024   |   Inventor(s): Sidi Bencherif
Keywords(s): Biomaterials, COVID-19, Vaccine
Category(s): Diagnostics, Technology Classifications > 1. Life Science > Biotechnology
Oxygen Releasing Cryogels
INV-18108 Background Hydrogels have been used for several biomedical applications because of their three dimensional nature, high water content, and wide range of polymers that can be used for their fabrication. Hydrogels as 3D scaffolds have recently gained momentum because they can mimic key features of the extracellular matrix, which is mainly...
Published: 9/10/2024   |   Inventor(s): Sidi Bencherif, Thibault Colombani, Michail Sitkovsky, Adnan Memic, Stephen Hatfield
Keywords(s):  
Category(s): Technology Classifications > 1. Life Science, Antimicrobial, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Delivery
Versatile Strategy for Covalent Grafting of Biomolecules to Cryogels
INV-20010 Background Biomaterial‑based scaffolds are being used as 3D culture systems in vitro and as molecular and cellular delivery vehicles in vivo. To support cellular survival, activation, and differentiation, cells need to be provided with biomolecular cues that trigger specific signaling pathways. To facilitate survival and expansion of...
Published: 9/10/2024   |   Inventor(s): Sidi Bencherif, JORIEKE WEIDEN, CARL FIGDOR, Martijn Verdoes
Keywords(s): 3D cell culture system, biomaterial-based scaffold, Biomolecules, Co-monomer, Covalent attachment, Cryogels, Versatile platform
Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering