Search Results - drug+design

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Software for Modeling Delivery and Penetration of Antibody Conjugates
Abstract: The National Cancer Institute (NCI) seeks parties to license software for modeling the targeted delivery of anti-cancer agents in solid tumors. The software models the permeability and concentration of intravenously administered antibody anti-cancer agent conjugates in solid tumors.  The models can be used to determine optimal dosing regimen...
Published: 5/21/2024   |   Inventor(s): Byungkook Lee, Youngshang Pak, Ira Pastan
Keywords(s): Anti-Cancer Modeling, Dosing, Drug Design, Tumor Delivery, Tumor Penetration
Category(s): Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology
Drug Candidate for ALS
RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...
Published: 1/29/2024   |   Inventor(s): Li Niu, Zhen Huang
Keywords(s): ALS, amyotrophic lateral sclerosis, aptamers, drug design, Lou Gehrig's disease, MND, motor neurone disease, RNA
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
3' Deoxy Nucleosides and Their Analogs as Anti-HIV Agents Targeting HIV-1 Macrophage Infection
3' Deoxy Nucleosides and Their Analogs as Anti-HIV Agents Targeting HIV-1 Macrophage Infection
Published: 10/28/2024   |   Inventor(s): Baek Kim
Keywords(s): Antiviral, Drug Design, HIV, Infectious Disease
Category(s): Therapeutic
MADDIT II Blood Samples
Applications:This set of biological materials arose from a genetics research study at the University of Rochester in the area of sudden cardiac death. The University also possesses genotypic and phenotypic data related to each sample (subject) that participated in this study. The data collected during the course of the study is owned by a third pa...
Published: 5/23/2023   |   Inventor(s): Arthur Moss
Keywords(s): Blood, Cardiac, Database, Drug Design
Category(s): Diagnostic