Search Results - dna+nanoswitches

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Improving the sensitivity and range of detection with ligation of DNA nanoswitches
This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 3/26/2026   |   Updated: 3/11/2026   |   Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya
Keywords(s): DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/26/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): aptamers, DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
Methods for detecting RNA modifications with DNA nanoswitches
This technology uses DNA nanoswitches to directly and specifically detect RNA modifications, allowing simultaneous identification of multiple modifications in their natural sequence context for research, diagnostics, and drug discovery applications. Background: RNA modifications, such as methylation, play critical roles in gene regulation, cellular...
Published: 3/26/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Iranna Todkari, Andrew Hayden
Keywords(s): DNA nanoswitches, RNA modifications, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Design and Synthesis
Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care
A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background: Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 3/18/2026   |   Updated: 5/13/2025   |   Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines
Design and Use of Multi-targeting DNA Nanoswitches for Increased Sensitivity Detection of Long RNAs
This technology provides a novel method for detecting COVID-19 and potentially other virus-based diseases. Background: The COVID-19 pandemic created an unprecedented need for large scale diagnostic testing. Unfortunately, the pandemic also created a number of challenges for traditional in vitro diagnostic techniques. These challenges include reagent...
Published: 2/6/2026   |   Updated: 4/14/2025   |   Inventor(s): Kenneth Halvorsen
Keywords(s): detection, DNA nanoswitches, Sensitivity, Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Diagnostics, Technology Classifications > Research Tools and Reagents