Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - neurological
10
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Phantasmidine, a Nicotinic Receptor Agonist for the Treatment of Addiction and
Neurological
Disorders
The inventors have isolated and characterized an alkaloid, phantasmidine, from the skin of the Ecuadoran poison frog E. anthonyi. Phantasmidine is selective for beta4-containing receptor subtypes, unlike many nicotinic receptor agonists currently in development, which target beta2-containing receptor subtypes. This selectivity makes phantasmidine...
Published: 7/25/2024
|
Inventor(s):
Richard Fitch
Keywords(s):
ADDICTION
,
AGONIST
,
Alkaloid
,
Alzheimer disease 1
,
Alzheimer disease 3
,
Alzheimer disease 4
,
Alzheimer disease type 1
,
Alzheimer disease type 4
,
Alzheimer disease, familial, type 3
,
EPIBATIDINE
,
IBXXXX
,
IXXXXX
,
nAChR
,
NBXXXX
,
NC2XXX
,
NCXXXX
,
Neurological
,
neurological
disease
,
nicotine
,
NICOTINIC
,
NXXXXX
,
Patent Category - Chemistry
,
Phantasmidine
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
TherapeuticArea > Neurology
,
Application > Research Materials
,
Application > Diagnostics
Novel Roles of a DNA Repair Protein, DNA-PKcs, in Obesity,
Neurological
Function, and Aging
The catalytic subunit of the DNA-dependent protein kinase complex (DNA-PKcs) has been shown to be important in DNA repair and VDJ recombination in lymphocytes. The inventors have discovered that DNA-PKcs also plays novel, important roles in energy regulation and
neurological
function. The inventors observed that mature DNA-PKcs-deficient mice (also...
Published: 7/25/2024
|
Inventor(s):
Jay Chung
Keywords(s):
Aging
,
ANXIETY
,
Cardiovascular
,
depression
,
DIABETES
,
DNA-Dependent
,
DNA-PKcs
,
Endurance
,
Energy
,
HEART
,
IB1XXX
,
IB3XXX
,
IB6XXX
,
IBXXXX
,
Inflammation
,
insulin
,
INSULIN-DEPENDENT
,
IXXXXX
,
LEARNING
,
MEMORY
,
METABOLIC
,
Metabolism
,
Mitochondria
,
Neurological
,
OBESITY
,
REGULATION
,
TYPE-2
,
Weight
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Application > Diagnostics
,
Application > Research Materials
,
Application > Vaccines
,
Application > Therapeutics
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Reproductive Health
,
TherapeuticArea > Immunology
EMG Lab Data Management Application- "EMG Lab"
Applications: This is a database management application in the form of a compiled Access 200 mde file that can be used by any EMG clinic that uses Nicolet Biomedical equipment. Advantages: The application imports data directly from Nicolet generated reports and provides functionaities for reporting, patient scheduling, decision support analysis...
Published: 5/7/2024
|
Inventor(s):
Eric Logigian
,
James Forrester
,
Doug Allen
Keywords(s):
Database
,
Neurological
,
Software
Category(s):
Diagnostic
Novel dopamine D2 receptor ligands for Parkinson’s disease & schizophrenia
Dopamine is a catecholamine neurotransmitter that mediates physiological functions in the central and peripheral nervous systems. Binding of dopamine to the dopamine D2 receptor elicits intracellular signaling implicated in various
neurological
disorders such as Parkinson’s disease (PD) and schizophrenia. Drugs targeting the dopamine D2 receptor...
Published: 3/4/2024
|
Inventor(s):
Thomas Keck
,
Chun Wu
Keywords(s):
Compounds
,
Dopamine D2
,
Neurological
,
Parkinson Disease
,
Schizophrenia
,
Therapeutic
,
Treatment
Category(s):
Human Health Care > Therapeutics
Activated Protein C Inhibits p53-Mediated Apoptosis and Acts as a Cell Survival Factor in the Central Nervous System
Applications:Activated protein C (APC), pro-drug, and/or a variant thereof may be used as an inhibitor of apoptosis or cell death and/or a cell survival factor, especially for stressed or injured cells or tissues of the nervous system including subjects with neurodegenerative disorders.Advantages:Novel biological functions (e.g., neuroprotection) can...
Published: 5/7/2024
|
Inventor(s):
Berislav Zlokovic
,
John Griffin
Keywords(s):
Aging
,
Alzheimer's
,
Neurological
,
Therapy
Category(s):
Therapeutic
Potent Compounds for the Treatment of Canavan Disease & Cancers
Project ID: D2016-55Invention Description:Elevated levels of N-acetylaspartate (NAA) is a major hallmark of Canavan disease (CD), which currently has no cure or standard course of treatment. Mutations in the aspA gene, which encodes aspartoacylase, render it unable to adequately catalyze the synthesis of NAA in CD patients. The Nat8l gene encodes aspartate...
Published: 7/31/2024
|
Inventor(s):
Ronald Viola
,
Bharani Thangavelu
,
Qinzhe Wang
,
Vinay Mutthamsetty
Keywords(s):
Canavan
,
Cancer
,
Enzyme
,
Inhibitor
,
Neurological
,
Target
Category(s):
Rare Disease
MUSC Neurology Therapeutics
MUSC Neurology Therapeutics: Therapeutics for Epilepsy and other
Neurological
Disordershttp://musc.technologypublisher.com/technology/12246 Compounds for Induction of Mitochondrial Biogenesishttp://musc.technologypublisher.com/technology/12247 Nucleosides Analogs for Cardiovascular and Neurodegenerative Diseaseshttp://musc.technologypublisher.co...
Published: 2/7/2023
|
Inventor(s):
Keywords(s):
cardiovascular
,
neurological
,
renal
Category(s):
BioPharma
Visual Prostheses Based Upon Fiber-Optic Uncaging of Neurotransmitter Substances
This drug delivery system selectively delivers drugs to various types of
neurological
cells to stimulate neurological tissue. This system can be used to develop visual and cortical prostheses. Background & Unmet Need: There are several types of prosthetic devices used for stimulation of neural tissue or neurons. There are visual prostheses used...
Published: 8/28/2019
|
Inventor(s):
Patrick Mcallister
,
Raymond Iezzi
,
Gregory Auner
,
Gary Abrams
Keywords(s):
Drug Delivery
,
Neurological
,
Neuroscience
Category(s):
Life Science
,
Neurological
disorders
,
Therapeutics
,
Drug Delivery
,
Diseases
Identification of a Novel Stem Cell Marker
Applications:The invention identifies a Novel Stem Cell Marker Gpr177, a G Protein-coupled Receptor. Gpr177 is a useful marker in the identification, isolation and characterization of specific stem cell population, including neural stem cells in specific regions of the brain and spinal cord, and cancer stem cells as well.Advantages:The Gpr177-expressing...
Published: 5/23/2023
|
Inventor(s):
Wei Hsu
Keywords(s):
Biomarkers
,
Neurological
,
Research Tool
,
Stem Cell
Category(s):
Research Tools
Transgenic Mouse Model of Parkinson's Disease Containing Either Wild-Type or Doubly-Mutated Human Alpha-synuclein
ApplicationsThis transgenic mouse model can be used to study Parkinson's Disease. The mouse model expresses a doubly mutated form of human alpha-synuclein. AdvantagesThis model has proven useful in understanding the pathogenesis of Parkinson's disease in humans and can be useful in designing rational interventions to slow or halt the course of the...
Published: 5/7/2024
|
Inventor(s):
Howard Federoff
,
Eric Richfield
Keywords(s):
Mouse
,
Neurological
,
Research Tool
Category(s):
Research Tools