Compositions and Methods for the Treatment of Intestinal Inflammation

NU 2021-252 

INVENTORS 

• Matthew Bury 
• Muthukumar Gunasekaran 
• Sunjay Kaushal 
• Arun Sharma*
• Tiffany Sharma 

BACKGROUND 

Crohn’s Disease (CD) is partly caused by a highly pro-inflammatory lesion microenvironment which subsequently causes numerous clinical complications. Northwestern University scientists have developed a method to control this inflammation with the use of neonatal Mesenchymal Stem Cells (nMSCs). This technology utilizes the anti-inflammatory and regenerative characteristics of nMSCs and directly injects them into developing small intestine inflammatory lesions which has shown the ability to positively modulate the inflammatory microenvironment.  

IP STATUS 

US patent pending.