Search Results - zackery+dentmon

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c‑Abl Modulators for Neurodegenerative Disease Treatment
Application Small‑molecule c‑Abl inhibitors designed to treat neurodegenerative diseases such as Parkinson’s and Alzheimer’s. Key Benefits Targets c‑Abl, a key regulator linked to neurodegeneration, oxidative stress, and loss of dopaminergic neurons. Provides new small‑molecule scaffolds with potential for improved safety profiles...
Published: 3/2/2026   |   Updated: 3/2/2026   |   Inventor(s): Thomas Kaiser, Zackery Dentmon, Christopher Dalloul, Dennis Liotta
Keywords(s): Drug Target Identification, Neurology and Pain Treatments, Rare and Orphan Disease Treatments, Small Molecule, Therapeutics
Category(s): TechPub Algolia > Drug Discovery
PI3Kα Inhibitors for the Treatment of Cancer
Application Compounds that inhibit the kinase activity of phospoinostidie 3-kinase (PI3Kα) for the treatment of cancer. Key Benefits Potential therapeutic targeted to pathway without a clinically approved inhibitor. Provides a useful pharmacological probe for research purposes. Market Summary In order to grow, cancer cells must have the...
Published: 11/20/2024   |   Updated: 7/17/2017   |   Inventor(s): Qi Shi, Thomas Kaiser, Dennis Liotta, James Snyder, Zackery Dentmon, John Diraddo
Keywords(s): Oncology, Small Molecule
Category(s): TechPub Algolia > Therapeutics