Search Results - metabolic+disease+treatments

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Combinatorial Therapy for Preserving Muscle Mass During Weight Loss
Application A combinatorial therapy to preserve muscle mass during semaglutide weight loss treatment. Key Benefits Preserves lean mass during semaglutide treatment in preclinical mouse models. Increases overall fat loss without affecting food/water intake during semaglutide treatment in preclinical mouse models. Market Summary The prevalence...
Published: 11/13/2025   |   Inventor(s): Todd Golde, Yong Ran, Eric Krause, Annette De Kloet, Karen Scott
Keywords(s): Antibodies, Biologics, Drug Discovery, Drug Target Identification, Metabolic Disease Treatments, Musculoskeletal Treatments, Personalized Medicine
Category(s): TechPub Algolia > Therapeutics
Novel Inhibitors of NOX2/ROS
Applications Novel therapeutics for treatment of various inflammatory airway conditions including chronic obstructive pulmonary disease (COPD). Key Benefits NOX2/ROS inhibitors have potential for use in a wide variety of clinical indications. Current treatments are weakly effective or provide only symptomatic relief for inflammatory airway diseases. Technical...
Published: 2/13/2025   |   Inventor(s): Thota Ganesh, John David Lambeth, Susan Smith, Aiming Sun
Keywords(s): Cardiovascular Treatments, Immunology and Inflammation Treatments, Metabolic Disease Treatments, Neurology and Pain Treatments, Respiratory Treatments, Small Molecule
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Functional Restoration of Diabetic Bone Marrow-Derived Cells
Application Methods for restoration of diabetic bone marrow cell function for cell based therapy, using pre-existing molecules and their derivatives. Key Benefits Ability to "reactivate" diabetic bone marrow-derived stem or progenitor cells which also include peripheral blood cells such as endothelial progenitor cells. Cells are more...
Published: 5/30/2025   |   Inventor(s): Young-Sup Yoon, Ji Woong (Jay) Han
Keywords(s): Cell Therapy, Metabolic Disease Treatments, Small Molecule
Category(s): TechPub Algolia > Therapeutics
Growth Factor as a Treatment for Obesity
Applications Therapeutic use of Glial Cell Line-Derived Neurotrophic Factor (GDNF) to treat obesity. Potential drug target for further therapeutic development. Key Benefits Growth Factor expression in the brain causes a reduction in high fat diet-induced obesity. Fat level reduction has been shown in both mouse and human cells. Reducing...
Published: 11/5/2025   |   Inventor(s): Shanthi Srinivasan
Keywords(s): Metabolic Disease Treatments
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Neurotrophic Factor as Therapeutic for Diabetes
Application The use of Glial Cell-derived Neurotrophic Factor (GDNF) or its mimics as a potential therapeutic for diabetes mellitus type 1 (IDDM). Key Benefits GDNF enhances pancreatic β-cell growth and survival in vitro and in vivo. GDNF transgenic mice have lower blood glucose levels and are more resistant to developing diabetes compared...
Published: 7/22/2025   |   Inventor(s): Shanthi Srinivasan
Keywords(s): Metabolic Disease Treatments
Category(s): TechPub Algolia > Therapeutics