Search Results - neurology+and+pain+treatments

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A 3D In Vitro Model of the Human Locus Coeruleus
Application A brain organoid model for the human locus coeruleus to study its function and dysfunction in neurological diseases. Key Benefits Locus coeruleus region-specific neural organoid model for studying this deep region of the human brain. The organoid synthesizes norepinephrine, allowing for study of diseases related to these neurotransmitters. The...
Published: 3/6/2025   |   Inventor(s): Fikri Birey, David Weinshenker
Keywords(s): 3D in vitro Models, Neurology and Pain Treatments
Category(s): TechPub Algolia > Research Tools
Implanted Passive Pressure Sensor Interrogated with (Ultra)-Sound (iPPSIS)
Application Easy-to-use, short and long-term, minimally invasive, MR-safe approach for directly measuring the variation of intracranial pressure. Key Benefits A minimally invasive device that is compatible with MRI imaging for quantitatively measuring intracranial pressure. A prototype has been developed showing the ability to measure shunt pressure...
Published: 2/13/2025   |   Inventor(s): David Myers, Nicholas Au Yong, Brooks Lindsey, Cecilia Alessandra Luna, Saeyoung (Sunny) Kim, Bowen Jing
Keywords(s): Medical Imaging (MRI, CT, Radiology), Neurology and Pain Treatments
Category(s): TechPub Algolia > Micro and Nanotechnology, TechPub Algolia > Medical Device
Antisense Restoration of ELAVL3 for Neurological Diseases
Application Antisense therapeutics targeting ELAVL3 expression for neurodegenerative disorders. Key Benefits Antisense approach for restoring protein levels and function of ELAVL3 and TDP-43. Preclinical data show the ability of several ELAVL3-targeting ASOs to restore protein expression via in vitro experiments. Potential to be a new medicine...
Published: 2/13/2025   |   Inventor(s): Zachary X McEachin
Keywords(s): Neurology and Pain Treatments
Category(s): TechPub Algolia > Therapeutics
Latent Variable Modeling for Developing Neuroprosthetic Devices
Application A high-performing neural decoder that reconstructs spiking data from local field potentials to analyze neural recordings for developing neuro-prosthetic devices. Key Benefits Capable of augmenting local field potential to overcome perturbations in data. Improved decoding stability with high accuracy. Potential to lead to the development...
Published: 2/13/2025   |   Inventor(s): Brianna Karpowicz, Chethan Pandarinath, Yahia Ali, Marc Slutzky, Robert Flint, Bareesh Bhaduri
Keywords(s): Algorithm, AI, and Machine Learning, Neurology and Pain Treatments
Category(s): TechPub Algolia > Medical Device, TechPub Algolia > Software
Faith-based Home Activity Toolbox (HAT)
Application Set of interventional activity tools designed to incorporated faith-based principles to improve the quality of life of individuals living with or family members caring for persons with moderate to severe Alzheimer Disease or related dementias. Key Benefits Provides relief from anxiety. Reduced behavior disturbances. Improved quality...
Published: 2/13/2025   |   Inventor(s): Fayron Epps
Keywords(s): Neurology and Pain Treatments, Patient and Support Education and Training
Category(s): TechPub Algolia > Non-Therapeutics
Flumazenil for Treatment of CNS Symptoms in Myotonic Dystrophy
Application A class of drugs that inhibit molecules responsible for the severe nervous system complications associated with myotonic dystrophy. Key Benefits Potentially the first medication for treating the severe nervous system symptoms associated with myotonic dystrophy by targeting GABRG2. Transdermal and oral administration. May drive the...
Published: 2/28/2025   |   Inventor(s): Gary Bassell, Andrew Jenkins, David Rye, Eric Wang, Maurice Swanson, Lyndon Lien
Keywords(s): Neurology and Pain Treatments
Category(s): TechPub Algolia > Therapeutics
Novel Therapeutic Target for Fragile X Syndrome and Neurodevelopmental Disorders
Application Salvianolic acid C for treating Fragile X Syndrome (FXS). Key Benefits New therapeutic drug candidate for the treatment of FXS. Preliminary data in the laboratory in organoids treated with the drug showed rescued cell phenotypes known to be associated with the disease in humans. Potential to treat other neurodevelopmental disorders. Market...
Published: 2/13/2025   |   Inventor(s): Peng Jin, Chuan He, Zhongyu Zou
Keywords(s): Neurology and Pain Treatments, Rare and Orphan Disease Treatments
Category(s): TechPub Algolia > Therapeutics
Machine Learning for Neurodegenerative Disease Diagnosis and Monitoring
Application A machine learning classification model incorporating biomarkers for detecting Parkinson's disease. Key Benefits The image processing methods are simple to use, and the processing pipeline is fully automated. The method is novel and customized to address the practical requirements of clinical and research imaging. Market Summary Parkinson’s...
Published: 2/13/2025   |   Inventor(s): Daniel Huddleston, Babak Mahmoudi
Keywords(s): Algorithm, AI, and Machine Learning, Medical Imaging (MRI, CT, Radiology), Neurology and Pain Treatments
Category(s): TechPub Algolia > Software, TechPub Algolia > Diagnostics
Blood-based Diagnostic Test for Anxiety
Application A blood-based biomarker test for the diagnosis of anxiety disorders. Key Benefits Gene panel of at least seven biomarkers that may predict anxiety in humans. Minimally invasive blood test. May identify different forms of anxiety leading to personalized treatment and improved clinical outcomes. Market Summary Anxiety disorders are...
Published: 2/13/2025   |   Inventor(s): Reid Alisch, Pankaj Chopra
Keywords(s): Biomarkers, Hematology and Blood Products, Neurology and Pain Treatments
Category(s): TechPub Algolia > Diagnostics
Method and System for Recording and Recovery of Electrophysiology During Stimulation
Application Systems and methods for recording and recovering viable electrophysiological signals and during delivery of stimulation, including deep brain stimulation (DBS). Key Benefits Enables the recording of electrophysiology/neurophysiology during stimulation from the same stimulating contact and adjacent contacts. Enables the potential usage...
Published: 3/6/2025   |   Inventor(s): Enrico Opri, Svjetlana Miocinovic
Keywords(s): Biomarkers, Neurology and Pain Treatments, Neurology Devices
Category(s): TechPub Algolia > Medical Device
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