Search Results - enzyme+and+protein+research

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Methioninase Inducing Virus for Anti-Cancer Therapy
Application A set of viral constructs that induce regulatable expression of methionine degrading enzyme for treatment of brain tumors. Key Benefits Built-in Tet-responsive element ensures precise regulation, preventing unwanted enzyme activity. IL-2 signal directs the enzyme for secretion, optimizing its therapeutic impact. Specific delivery...
Published: 1/20/2026   |   Inventor(s): Timothy R. Gershon, Leon McSwain, Andrey Tikunov
Keywords(s): Drug Discovery, Enzyme and Protein Research, Oncology Treatments, Therapeutics
Category(s): TechPub Algolia, TechPub Algolia > Therapeutics
Precision Protein Repair Platform for Missense Mutations
Application This technology enables targeted chemical correction of missense mutations in proteins using a modular heterotrifunctional molecule platform. Key Benefits Restores protein function by chemically mimicking healthy amino acid side chains. Modular toolkit allows rapid customization for diverse protein targets. Validated across multiple...
Published: 11/12/2025   |   Inventor(s): Monika Raj
Keywords(s): Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Protein and Peptide Therapeutics, Research Tools
Category(s): TechPub Algolia > Therapeutics
Anticancer Agent with N-Glycan Specificity
Application An engineered protein for targeting disease-associated N-glycans. Key Benefits High affinity, pH insensitive, no cofactors required. Applications in anticancer and antiviral therapeutics and research. Can aid in manufacturing monoclonal antibodies with desired N-glycosylation properties. Market Summary Glycosylation involves post-translation...
Published: 1/20/2026   |   Inventor(s): Eric J. Sundberg, Diego Sastre, Maros Huliciak
Keywords(s): Antibodies, Biologics, Biomarkers, Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Microbiology and Infectious Disease Treatments, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
Functionalized Collagen Biochips with Core-Shell Structures and Collagen-Mimetic Peptide Nanotubes
Application Synthetic collagen-based biomaterials for therapeutic delivery or drug testing. Key Benefits Synthetic collagen substitute. Capable of formulating into various structures. Free of animal-based contaminants. Able to be spatially patterned. Market Summary Organ failure and tissue defects affect millions of Americans, resulting in...
Published: 1/20/2026   |   Inventor(s): Vincent Conticello, Andrea Merg, Gavin Touponse
Keywords(s): Biomaterials, Enzyme and Protein Research
Category(s): TechPub Algolia > Micro and Nanotechnology
Targeted Immunotherapy for KRAS-Driven Cancers
Application Targeted immunotherapy and companion biosensing approach for cancers harboring the KRASG12V mutation. Key Benefits First-in-class therapeutic strategy specifically designed for KRASG12V-positive cancers. Addresses a significant unmet need in oncology where no approved KRASG12V-targeted therapies currently exist. Restores the body’s...
Published: 2/23/2026   |   Inventor(s): Haian Fu, Cong Tang, Xiulei Mo
Keywords(s): Drug Target Identification, Enzyme and Protein Research, Immunology and Inflammation Treatments, Oncology Treatments
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Caspase-3 Deficient MEFs with Mutant Caspase-3 Re-Introduced
Application Mouse embryonic fibroblast (MEF) line deficient in caspase-3 that are reconstituted with constitutively expressed mutant versions of the protease. Key Benefits An immortalized caspase-3-deficient MEF cell line. Tool to study protease induced apoptosis. Technical Summary Emory inventors have discriminated a previously unknown role...
Published: 1/20/2026   |   Inventor(s): Lawrence Boise, Katelyn Ponder
Keywords(s): Cell Lines and Organoids, Enzyme and Protein Research
Category(s): TechPub Algolia > Research Tools
Photocaged Cytokines for Cancer Immunotherapy
Application Light-responsive cytokine prodrugs with controlled activation for improved cancer immunotherapy. Key Benefits Spatiotemporal control of therapeutic cytokine activation leads to controlled local activation and reduces off-target toxicity. Prolonged circulation means less frequent dosing is required. Biased activity towards CD8+ T-cells...
Published: 9/3/2025   |   Inventor(s): Erik Dreaden, Lacey Perdue, Priscilla Do
Keywords(s): Biologics, Enzyme and Protein Research, Immunology and Inflammation Treatments, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
Ribosome Pegging: An Antibiotic-free System to Produce Recombinant Proteins
Application Antibiotic-free method to prevent the growth of cells that fail to express high levels of a non-essential protein (target protein). Key Benefits Prevents the use of antibiotics and markers that promote resistance. Facilitates the deployment of recombinant bacteria in uncontrolled environments. Stabilizes heterologous expression of...
Published: 2/13/2025   |   Inventor(s): Ichiro Matsumura
Keywords(s): Enzyme and Protein Research, Platform, Production Methods
Category(s): TechPub Algolia > Research Tools
Selective Enrichment of A-To-I Edited Transcripts from Cellular RNA Using Endonuclease V
Application Kit to efficiently identify and enrich adenosine-to-inosine (A-to-I) editing in RNA molecules. Key Benefits Robust and facile method for enriching A-to-I edited transcripts. Overcomes the low efficiency and accuracy of transcriptome-wide RNA-seq. Market Summary A-to-I RNA editing by adenosine deaminases is a common RNA modification...
Published: 1/26/2026   |   Inventor(s): Steven Knutson, Jennifer Heemstra
Keywords(s): Enzyme and Protein Research
Category(s): TechPub Algolia > Research Tools
DNAzyme Nanoparticles for the Cleavage of RNA
Application Site-selective RNA splicing nanozyme for cleaving and ligating RNA. Key Benefits Can cleave virtually any RNA stem loop. Removes a 19 nucleotide segment from a 67 nucleotide RNA loop with up to 66% efficiency. Technical Summary Modulating RNA can be useful for studying RNA biology, gene knockdown, and regulating RNA splicing. Scientists...
Published: 1/20/2026   |   Inventor(s): Jessica Petree, Kevin Yehl, Khalid Salaita
Keywords(s): Enzyme and Protein Research, Gene Therapy and Editing
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Micro and Nanotechnology
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