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Search Results - allan+levey
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Human Brain Proteins with Evidence Consistent with Causality of Alzheimer’s and Depression
Application Research and therapeutic targets for Alzheimer’s disease, depression, and other neurological conditions mediated by protein expression in the brain. Key Benefits These findings can be utilized as a research tool to better understand the genetic basis of Alzheimer’s disease. Can also be utilized to develop therapeutics for...
Published: 9/26/2024
|
Inventor(s):
Aliza Wingo
,
Thomas Wingo
,
Yue Liu
,
Allan Levey
,
Nicholas (Nick) Seyfried
,
Duc Duong
Keywords(s):
Neuroscience/Pain
,
Target
Category(s):
TechPub Algolia > Research Tools
,
TechPub Algolia > Therapeutics
RNA Biomarkers for Alzheimer’s Disease
Application RNA for U1 small nuclear ribonucleoprotein (snRNP) subunits as biomarkers for Alzheimer’s disease (AD). Key Benefits Identifies unique U1 snRNP pathology in AD patients that implicates abnormal RNA splicing in AD pathogenesis. Facilitates early diagnosis and intervention strategies for treatment of AD. Potential use as therapeutic...
Published: 7/30/2024
|
Inventor(s):
Allan Levey
Keywords(s):
Biomarker
,
Neuroscience/Pain
Category(s):
TechPub Algolia > Diagnostics
ß-secretase (BACE) Monoclonal Antibody
Applications Immunohistochemistry Western Blot Immunprecipitation Specificity β -secretase (BACE) of mouse, rat, and human origin. Subtype Mouse Monoclonal Technical Summary β -secretase (BACE) is an aspartic-acid protease important to the formation of the amyloid-β peptides that form senile plaques in brains of Alzheimer's...
Published: 9/26/2024
|
Inventor(s):
Allan Levey
Keywords(s):
Antibody
Category(s):
TechPub Algolia > Research Tools
Presenillin 1 N-Terminal Monoclonal Antibody
Applications Immunoblotting Immunocytochemistry Specificity Human Presenilin-1 N-terminal Subtypes Rat monoclonal Technical Summary By immunoblotting applications the antibody recognizes a predominant 32 kDa polypeptide in a varitety of samples including PC12 cells transfected with human PS1, complimentary DNA brain biopsy specimens from...
Published: 9/26/2024
|
Inventor(s):
Allan Levey
Keywords(s):
Antibody
Category(s):
TechPub Algolia > Research Tools
Presenillin 1 C-Terminal Monoclonal Antibody
Applications Immunoblotting Immunohistochemistry Specificity Human Presenilin-1 C-terminal Subtypes Mouse Monoclonal Technical Summary By immunoblotting applications the antibody recognizes a predominant 32 kDa polypeptide in a varitety of samples including PC12 cells transfected with human PS1, complimentary DNA brain biopsy specimens from...
Published: 9/26/2024
|
Inventor(s):
Allan Levey
Keywords(s):
Antibody
Category(s):
TechPub Algolia > Research Tools
Monoclonal Antibody for High-Affinity Choline Transporter
Application Immunocytochemistry Western Blot Immunoprecipitation Specificity Human, rat & mouse high-affinity choline transporter (CHT). No detectable cross reactivity with other proteins by western blot. Subtype Mouse IgG1 (monoclonal) Technical Summary Acetylcholine functions as a neurotransmitter in both the central and peripheral...
Published: 9/26/2024
|
Inventor(s):
Allan Levey
,
Randy Blakely
,
Craig Heilman
Keywords(s):
Antibody
Category(s):
TechPub Algolia > Research Tools
Muscarinic Acetylcholine Receptor m2 Antibody
Applications Immunohistochemistry Western blotting Specificity m2 muscarinic acetylcholine receptor Subtype Rat Monoclonal Technical Summary The m2 muscarinic acetylcholine receptor is a membrane bound G-protein coupled receptor highly expressed throughout the basal forebrain, as well as in cardiac tissue. These monoclonal antibodies were...
Published: 9/26/2024
|
Inventor(s):
Allan Levey
,
Craig Heilman
Keywords(s):
Antibody
Category(s):
TechPub Algolia > Research Tools