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Search Results - protein+and+peptide+therapeutics
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Precision Neo-Cysteine Molecular Glues to Restore Protein-Protein Interactions in Disease
Application Molecular glues designed to selectively bind mutated neo-cysteine residues and restore disease-disrupted protein–protein interactions (PPIs), offering a precision therapeutic approach for conditions such as cancer where loss or weakening of critical protein interactions drives tumor growth and progression. Key Benefits Provides...
Published: 3/2/2026
|
Inventor(s):
Xiulei Mo
,
Haian Fu
Keywords(s):
Oncology Treatments
,
Personalized Medicine
,
Protein and Peptide Therapeutics
,
Therapeutics
Category(s):
TechPub Algolia > Drug Discovery
Targeted Candidalysin Binders for Fungal Infection Control
Application A theranostic scaffold-derived protein that neutralizes candidalysin toxin. Key Benefits Different mechanism of action compared to current antifungal drugs, reducing the risk of resistance. Derived from human protein for lower immune response and produced cost-effectively in simple bacterial media. Small size improves tissue penetration...
Published: 2/23/2026
|
Inventor(s):
Sohail Khoshnevis
,
Eric J. Sundberg
,
Maros Huliciak
Keywords(s):
Diagnostics
,
Drug Discovery
,
Hydrogels
,
Protein and Peptide Therapeutics
,
Therapeutics
Category(s):
TechPub Algolia > Therapeutics
Precision Protein Repair Platform for Missense Mutations
Application This technology enables targeted chemical correction of missense mutations in proteins using a modular heterotrifunctional molecule platform. Key Benefits Restores protein function by chemically mimicking healthy amino acid side chains. Modular toolkit allows rapid customization for diverse protein targets. Validated across multiple...
Published: 11/12/2025
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Inventor(s):
Monika Raj
Keywords(s):
Drug Discovery
,
Drug Target Identification
,
Enzyme and Protein Research
,
Protein and Peptide Therapeutics
,
Research Tools
Category(s):
TechPub Algolia > Therapeutics
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 1/20/2026
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Inventor(s):
Felipe Quiroz
,
Ian Sicher
,
Spencer Hayes
,
Maria Giraldo-Castaño
,
Mariell Pascual
,
Alexa Avecilla
Keywords(s):
Biomaterials
,
Cell Therapy
,
Immunotherapy
,
Protein and Peptide Therapeutics
,
Regenerative Medicine
,
Research Tools
Category(s):
TechPub Algolia > Therapeutics
MKK3/MYC Protein-Protein Interaction Inhibitor Overcomes Resistant Non-Small Cell Lung Cancer
Application A therapeutic use for SGI-1027 in the treatment of Osimertinib-resistant non-small cell lung cancer (NSCLC). Key Benefits The MKK3/MYC protein-protein interaction inhibitor SGI-1027 effectively decreases MYC levels in Osimertinib-resistant NSCLC cell lines. The combination of SGI-1027 with Osimertinib offers synergistic benefits over...
Published: 3/2/2026
|
Inventor(s):
Andrey Ivanov
,
Haian Fu
,
Shi-Yong Sun
,
Zhen Chen
Keywords(s):
Drug Discovery
,
Oncology Treatments
,
Protein and Peptide Therapeutics
Category(s):
TechPub Algolia > Therapeutics