Search Results - rakesh+paul

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Optimized Carbohydrates for Tumor Targeting
The bleomycins (BLMs) are well-known antineoplastic agents, clinically useful in the treatment of squamous cell carcinomas and malignant lymphomas. The carbohydrate moiety, particularly the disaccharide moiety, of BLM is also known to be highly tumor targeting. Researchers at the Biodesign Institute of Arizona State University have discovered disaccharides...
Published: 2/23/2023   |   Inventor(s): Sidney Hecht, Manikandadas Mathilakathu Madathil, Chandrabali Bhattacharya, Trevor Bozeman, Rakesh Paul, Zhiqiang Yu, Michael Rishel
Keywords(s): Diagnostics, Drug Target Identification, Imaging, Medical Devices and Imaging, Molecular Diagnostics
Category(s): Life Science (All LS Techs), Imaging, Medical Imaging, Pharmaceuticals
Carbohydrate-Targeted Antitumor Agents
The bleomycins (BLMs) are well-known antineoplastic agents, clinically useful in the treatment of squamous cell carcinomas and malignant lymphomas. The carbohydrate moiety of BLM is also known to be highly tumor targeting. Methotrexate is a highly effective antitumor agent as well and is used to treat cancers of the skin, head and neck, lung and breast....
Published: 2/23/2023   |   Inventor(s): Sidney Hecht, Rakesh Paul, Chenhong Tang
Keywords(s): Anti-neoplastic Drugs, Cancer, Drug Delivery, Therapeutics
Category(s): Cancer Therapeutics, Imaging, Life Science (All LS Techs), Medical Imaging, Pharmaceuticals
Incorporation of Fluorescent Dipeptidomimetics into Peptides and Proteins
There is tremendous diversity in the structure and function of peptides and proteins, thus peptide and protein engineering is an area of intense interest. There are many means to accomplish peptide and protein engineering, but the overarching goal is to design and engineer the chemical structure to improve the molecular properties and achieve increased...
Published: 2/23/2023   |   Inventor(s): Sidney Hecht, Larisa "liza" Dedkova, Rumit Maini, Sandipan Roy Chowdhury, Rakesh Paul
Keywords(s): Biological Macromolecules, Enzymes, Novel Biomaterials, Protein
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools