Search Results - nanoparticles

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3D Scaffold for T Cell Delivery and Suppression of Tregs for Solid Tumors (UCLA Case No. 2020-193)

SUMMARY: UCLA researchers in the Department of Bioengineering have developed a small and biodegradable implant that when placed adjacent to solid tumors, enhances immune response to cancer cells. BACKGROUND: The body’s immune system uses proteins called antibodies to train the immune response to foreign pathogens. This mechanism can combat...

Published: 12/3/2024 | Inventor(s): Manish Butte

Keywords(s): cytokines, Drug Delivery, Immunotherapy, Nanoparticles, scaffolds, solid tumors, T-cell activation, t-cells

Category(s): Platforms > Drug Delivery > Nanoparticles

NanoScript & MitoScript – Nanoparticles for Modulation of Endogenous DNA at the Transcription Level

NanoScript (left) for the regulation of DNA transcription and MitoScript (right) for the regulation of mDNA transcription. Invention Summary: As of 2022, 1 in 4000 people are affected by mitochondrial disorders. Currently there are no cures for many mitochondrial disorders and treatment plans typically only address alleviating...

Published: 11/25/2024 | Inventor(s): Ki-Bum Lee, Sy-Tsong Chueng, Hyeon-Yeol Cho, Young Sup Yoon

Keywords(s): Nanoparticles

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology

miRNA Nanoparticles for Targeted Enhancement of Thermogenic Adipocyte Generation

Introduction of a promising anti-obesity novel MiR-133a, Zipper nanoparticle treatment results in enhanced Prdm16 and Ucp1 expression, resulting in adipocyte browning. Invention Summary: Over 40% of adults are overweight and over 15% of adults are living with obesity. Obesity is a major contributor to various causes of mortality including...

Published: 11/12/2024 | Inventor(s): Sarah Nevins, Ki-Bum Lee, Thanapat Pongkulapa, Sang Ah Yi

Keywords(s): Cardiovascular, Diabetes & Metabolic Disorders, Nanoparticles, Nanotechnology

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology

Anti-Inflammatory Drug Eluting Patches for Treatment of Ocular Injuries (UCLA Case No. 2022-156)

UCLA researchers in Department of Chemical and Biomolecular Engineering developed a visible light crosslinkable hydrogel-based drug delivery platform that can achieve sustainable release of anti-inflammatory drug molecules to address unmet need of drug bioavailability in ocular injury treatment. BACKGROUND: The Centers for Disease Control and Prevention...

Published: 9/26/2024 | Inventor(s): Nasim Annabi

Keywords(s): eye disease, gelpatch, hyaluronic acid, micelles, Nanoparticles, ocular, ocular inflammation, Ophthalmic antibiotics, Ophthalmology

Category(s): Therapeutics > Ophthalmology

Method of Treating Obesity-Induced Glucose Intolerance and Liver Fibrosis (UCLA Case No. 2021-323)

UCLA researchers in the School of Engineering have discovered a novel method to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...

Published: 9/24/2024 | Inventor(s): Zhen Gu

Keywords(s): glucose intolerance, liver fibrosis, Nanoparticles, Notch signaling pathway, obesity

Category(s): Therapeutics > Metabolism And Endocrinology

Nisin-Based Formulations for Oral and Systemic Conditions (UCLA Case Nos. 2023-133 and 2022-306)

UCLA researchers in the Department of Dentistry have found a novel use for nisin alone, and in formulations, for use in the treatment of Alzheimer’s disease, and multiple inflammation states such as brain inflammation, joint inflammation, oral inflammation, systemic inflammation, inflammatory bowel diseases, and non-alcoholic fatty liver disease...

Published: 9/19/2024 | Inventor(s): Yvonne Kapila

Keywords(s): Alzheimers disease, Antibacterial, gut inflammation, Inflammation, microbiome, nanoparticle delivery system, Nanoparticles, nisin, oral inflammation, periodontal disease, periodontal inflammation, periodontal regeneration

Category(s): Therapeutics > CNS and Neurology

Dynamic Extension of the Eyebox for Maxwellian View AR Waveguides (Case No. 2024-163)

Summary: Researchers in the Department of Electrical & Computer Engineering have developed a new metasurface material that improves the size and resolution of augmented reality overlays. Background: Augmented reality (AR) waveguide displays have revolutionized the way users can interact with virtual content overlaid in the real world. High...

Published: 11/4/2024 | Inventor(s): Chee Wei Wong, Hyunpil Boo

Keywords(s): artificial electromagnetic materials, artificial-intelligent materials, Augmented Reality, augmented reality (AR), bacterial nanocellulose, Carbon Nanotube, Composite Materials, Construction Materials, Extended reality, Functional Materials, intercalated materials, liquid crystal nanofibers, Materials, Medical Devices and Materials, meta materials, metal nanocomposites, metasurfaces, microarchitectured materials, Microfluidics Nanosphere, Mixed Reality, nanobody, nanocomposite scintillators, Nanocomposites, Nanocrystal, nanocrystalline metals, nanodispersion, Nanoelectronics, Nanoemulsion droplet, Nanofiber, nanograined metals, Nanomaterials, Nanoparticle, Nanoparticles, nanophotonic, nanophotonic structures, nanophotonics, Nanosensor, Nanostructure, nanostructured materials, Nanotechnology, Optoelectronic materials, photonic materials, Raw materials supplier, Toxicity Of Nanomaterials, Ultrahard materials/abrasives, Virtual Reality, Virtual Reality Braille Haptic Technology Joule Heating, Virtual Reality Occupational Therapy Exercise Machine, Water Purification, Nanofiltration, Ultrafiltration, zzsemiconducting materials

Category(s): Software & Algorithms, Software & Algorithms > Ar/Vr, Materials, Materials > Composite Materials, Materials > Functional Materials, Materials > Nanotechnology

Nanocomposite Scintillators (Case No. 2024-126)

Summary: UCLA researchers from the Department of Materials Science and Engineering have developed a novel nanocomposite material for high-efficiency radiation detection and monitoring. Background: Scintillators are materials that emit light when they absorb radiation, such as gamma rays or x-rays. The photons generated by the scintillators can...

Published: 5/15/2024 | Inventor(s): Qibing Pei, Ziqing Han

Keywords(s): adhesive material, Algorithm Optical Coherence Tomography, anode material, artificial electromagnetic materials, artificial-intelligent materials, background radiation, Biomaterial, Biomaterial 3D Printing, bulk material, Composite Material, composite scintillators, Computed tomography, Computerized Tomography scan (CT), Diffraction Tomography, Drug Delivery Microporous Material, fast scintillators, gamma spectroscopy, High resolution computed tomography, high-Z organometallics, hole transporting material, Hyperelastic Material, intercalated materials, material characterization, Materials, meta materials, metal nanocomposites, microarchitectured materials, nanocomposite scintillators, Nanocomposites, Nanomaterials, Nanoparticle, Nanoparticles, nanostructured materials, neutrino detection, Optical Tomography, Optoelectronic materials, photonic materials, positron emission tomography (PET), radiation detection, Raw materials supplier, scintillators, second harmonic generation, Smart Material, Solar Cell Metamaterial, Surgical Instrument Optical Coherence Tomography, suturable biomaterial, X-Ray Computed Tomography

Category(s): Chemical, Chemical > Chemical Sensors, Materials, Materials > Functional Materials

Electrically Active Magnetic Nanoparticle-based Biosensors

Executive Summary Harmful microbes are present in various sources including water, food, plants, and through human-to-human transmission. The ability to detect them rapidly at a low cost is important to protecting the health and safety of humans and animals and the security of food chains. MSU researchers have developed novel nanoparticle-based biosensors...

Published: 3/29/2024 | Inventor(s): Evangelyn Alocilja, Sudeshna Pal, Emma Setterington

Keywords(s): Biosensors, Magnetic Beads, Magnetic Separation, Molecular Sample Processing, Nanoparticles, Polyaniline

Category(s): Biotechnology, Test and Measurement, Devices, Electrical

Ultrafine Platinum Catalysts for Hydrogen Fuel Cells (Case No. 2023-026)

Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel method to synthesize platinum-based catalysts with ultralow base transition metal-oxide content. Background: Ultrafine platinum (Pt)-based catalysts present a promising avenue for achieving exceptional fuel cell activity while minimizing base transition...

Published: 9/17/2024 | Inventor(s): Yu Huang

Keywords(s): Catalysts, Fuel Cell, Metals, Nanoparticle, Nanoparticles, Nanotechnology, Platinum, transition metal catalysts

Category(s): Materials, Energy & Environment, Energy & Environment > Energy Storage, Energy & Environment > Energy Storage > Fuel Cells, Chemical, Chemical > Catalysts, Chemical > Synthesis, Materials > Nanotechnology

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