Search Results - genomics%2c+proteomics

5 Results Sort By:
Single Cell In-Situ Extraction with Intact 3D Morphology from Formalin Fixed Paraffin Embedded (FFPE) Tissues
FFPE is a well-established and widely used method for preservation and histological analysis of tissue samples. DNA/RNA/and Proteins can be extracted from FFPE samples, but generally lack single cell resolution and completely lack 3D spatial resolution. Enabling 3D resolution allows the correlation of morphology to information like gene expression,...
Published: 4/25/2023   |   Inventor(s): David Richardson, Thai Tran, Dmitry Derkach, Colleen Ziegler
Keywords(s): Bioanalysis, Biological Cell Manipulation, Bio-Technology, Cancer, Device, Diagnostics, Gene Expression, Genomics, Proteomics, In situ, Molecular Diagnostics, Single-cell analysis
Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Processing-In-Memory (PIM) Platform for mRNA Quantification
­The study of human genetics is a rapidly expanding field, fueled in part by developments in large-scale protein and genomic sequencing technologies. Biopharmaceutical companies and modern healthcare rely heavily on sequencing technologies and the acquired data to develop new drugs and provide effective treatments to patients. However, the results...
Published: 2/23/2023   |   Inventor(s): Deliang Fan, Fan Zhang, Shaahin Angizi
Keywords(s): Algorithm Development, Biomarker discovery, Computing Architecture, DNA and protein sequencing, Genomics, Proteomics, Sequencing
Category(s): Physical Science, Computing & Information Technology, Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools
ErbB4 Inhibitors and Methods of Use
ErbB4 is a receptor tyrosine kinase member with roles in several key pathways associated with cell proliferation, death and differentiation. ErbB4 overexpression is associated with several types of cancers as well as psychiatric and cardiovascular disorders. Currently there are no drugs available for ErbB4-driven pathologies, or methods of identifying...
Published: 2/23/2023   |   Inventor(s): Fernanda Festa, Joshua LaBaer, Jin Park, Femina Rauf
Keywords(s): Biosignature, Cancer, Diagnostics, Genomics, Proteomics, Protein Kinase Inhibitors
Category(s): Pharmaceuticals, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools
Microreactor Array Instrument/Platform
High throughput parallel assays are needed to effectively identify and study biomolecules and their activity. Typically it takes a large number of repeated assays to get statistically significant data for studying biomolecules. However, fewer assays would be needed to get statistically meaningful results if the data were of higher quality. Because of...
Published: 2/23/2023   |   Inventor(s): Peter Wiktor
Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioassay, Bio-Technology, Detection, Diagnostics, Diffusion, DNA nanotechnology, Drug Discovery, Drug Screening, Drug Target Identification, ELISA, Genomics, Proteomics, Health Monitoring, High Throughput Sensors, Immunology, In situ, In Vitro, Instrumentation, Liquid Handling and Dispensing, MicroArray, Microbiology, Micro-Fluidics, Microreactor, Molecular Diagnostics, Nucleic Acid, Personalized medicine, Pharmaceutical, Polymerase Chain Reaction (PCR), Protein, Protein Assays
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
Biomarkers for Irritable Bowel Syndrome (IBS)
Approximately 9% of the general population will report the onset of Irritable Bowel Syndrome (IBS) over a one year period. Unfortunately, at present, there is no standard and reliable diagnostic test for IBS. IBS is currently diagnosed using symptomatic criteria, but because symptoms of IBS can overlap with other GI diseases, there is considerable uncertainty...
Published: 2/23/2023   |   Inventor(s): Todd Sandrin, Peter Jurutka
Keywords(s): Biosignature, Bio-Technology, Gene Expression, Genomics, Proteomics, MicroArray, Molecular Diagnostics
Category(s): Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors