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Search Results - todd+sandrin
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Multiomic Approaches to Pediatric Inflammatory Bowel Disease
Invention Description Pediatric Inflammatory Bowel Disease (IBD), encompassing Crohn’s Disease and Ulcerative Colitis, presents significant clinical challenges due to its complex and heterogeneous nature, often leading to lifelong health complications. Current diagnostic and therapeutic strategies are limited by an incomplete understanding of...
Published: 11/12/2025
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Inventor(s):
Todd Sandrin
,
Peter Jurutka
,
Haiwei Gu
,
Brad Pasternak
Keywords(s):
Category(s):
Applied Technologies
,
Diagnostic Assays/Devices
,
Life Science (All LS Techs)
,
Pharmaceuticals
,
Proteomic Assays/Reagents/Tools
Laser Capture Microdissection (LCM) Microfluidic Platform for Single-Cell Proteomic Analysis
Single-cell proteomics is an emerging field for proteomic analyses of individual cells. Single-cell genomic analyses have greatly expanded our understanding of cell heterogeneity and disease progression; however, protein identification and quantitative cell-to-cell variation provide a deeper level of understanding of the biological regulators in the...
Published: 2/13/2025
|
Inventor(s):
Alexandra Ros
,
Jorvani Cruz Villarreal
,
Ana Egatz-Gomez
,
Todd Sandrin
,
Paul Coleman
Keywords(s):
Category(s):
Proteomic Assays/Reagents/Tools
,
Neurodegenerative Disease Technologies
,
Life Science (All LS Techs)
,
Bioanalytical Assays, Chemistries & Devices
Biomarkers for Irritable Bowel Syndrome (IBS)
Approximately 9% of the general population will report the onset of Irritable Bowel Syndrome (IBS) over a one year period. Unfortunately, at present, there is no standard and reliable diagnostic test for IBS. IBS is currently diagnosed using symptomatic criteria, but because symptoms of IBS can overlap with other GI diseases, there is considerable uncertainty...
Published: 2/13/2025
|
Inventor(s):
Todd Sandrin
,
Peter Jurutka
Keywords(s):
Biosignature
,
Bio-Technology
,
Gene Expression
,
Genomics, Proteomics
,
MicroArray
,
Molecular Diagnostics
Category(s):
Genomic Assays/Reagents/Tools
,
Life Science (All LS Techs)
,
Medical Diagnostics/Sensors