Search Results - biomarker+discovery

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Laser Ablation Direct Analysis in Real Time-Imaging Mass Spectrometry (LADI-MS)
Offers the potential of real-time small-sample analysis for a very large variety of applications. Background: Real Time Imaging Mass Spectrometry (RTMS) is a method for analyzing and identifying biological samples in real time. RTMS can be used in an extremely broad variety of applications, involving chemistry, biochemistry, food sciences, and medicine....
Published: 1/23/2024   |   Inventor(s): Rabi Musah
Keywords(s): analytical chemistry, Biomarker discovery, chemistry, forensic testing, image acquisition, imaging, life sciences, Mass spectrometry imaging, medical imaging, Natural products, Phytochemistry, Small-molecule profiling, Small-molecule spatial distribution mapping, Species discrimination, Species identification, Technologies, Tissue analysis, wood anatomy, wood science
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Environment, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents
Processing-In-Memory (PIM) Platform for mRNA Quantification
­The study of human genetics is a rapidly expanding field, fueled in part by developments in large-scale protein and genomic sequencing technologies. Biopharmaceutical companies and modern healthcare rely heavily on sequencing technologies and the acquired data to develop new drugs and provide effective treatments to patients. However, the results...
Published: 2/23/2023   |   Inventor(s): Deliang Fan, Fan Zhang, Shaahin Angizi
Keywords(s): Algorithm Development, Biomarker discovery, Computing Architecture, DNA and protein sequencing, Genomics, Proteomics, Sequencing
Category(s): Physical Science, Computing & Information Technology, Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools
Biomarkers for Diagnosis of Lung Cancer
Lung cancer is the leading cause of cancer deaths in the United States, with more than 150,000 deaths in 2014. While the increased use of CT screening for lung cancer has resulted in a reduction in lung cancer mortality, it has also resulted in an increased detection of benign pulmonary nodules. Patients often undergo unnecessary, costly and invasive...
Published: 2/23/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Jie Wang, Garrick Wallstrom, Jin Park, William Rom, Harvey Pass
Keywords(s): Autoantibody, Biomarker discovery
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Biomarkers for Early Detection of Serous Ovarian Cancer
Ovarian cancer is one of the most common cancers among women, with over 21,000 new cases and over 14,000 deaths per year. If detected early, the 5-year survival rate is over 80%, but that drops to just 11% if detected at stage IV, and over 60% of patients are diagnosed with advanced disease. Early detection is hampered by limitations in current biomarkers,...
Published: 2/23/2023   |   Inventor(s): Benjamin Katchman, Karen Anderson, Garrick Wallstrom, Joshua LaBaer, Daniel Cramer
Keywords(s): Antibodies, Autoantibody, Biomarker discovery, Cancer, Diagnostics, Early Detection, Immunosignature, Ovarian Cancer
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Autoantibody Biomarkers for Crohn’s Disease
Crohn’s disease (CD), is an inflammatory bowel disease that affects about 3 out of 1,000 people in the U.S. It is currently not known what causes CD, but hereditary, environmental factors and a dysregulated immune system are thought to play a role. Diagnosis of CD is difficult and often involves expensive imaging and invasive biopsies. Current...
Published: 10/19/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Haoyu Wang, Shabana Pasha, Jonathan Leighton
Keywords(s): Antibodies, Autoantibody, biomarker, Biomarker discovery, Diagnostics
Category(s): Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Enhanced Applications of Molecular Libraries
There are many methods to analyze molecular libraries (e.g. peptide libraries, nucleic acid libraries, libraries of polymeric or multipart structures) in terms of their functional properties. Often, these methods relate the covalent structure of the molecules in libraries to their function based on consensus sequence analysis. However, many biological...
Published: 2/23/2023   |   Inventor(s): Neal Woodbury, Alexander Taguchi
Keywords(s): Algorithm Development, Array Techs - Micro, Nano, Gen,Proteomic, Biomarker discovery, MicroArray, Peptide Affinity Reagents, Peptide Microarray
Category(s): Life Science (All LS Techs), Computing & Information Technology, Applied Technologies
Integrated Microarray Printing and Detection System
Microarray technology has dramatically advanced the study of protein interactions and validation of new biomarkers and therapeutics. However, current microarray technology suffers from several key limitations that hinder it from gaining broader utility: 1) both the printing and analysis steps consume large sample volumes, which is particularly problematic...
Published: 2/23/2023   |   Inventor(s): Nongjian (nj) Tao, Shaopeng Wang
Keywords(s): Bioimaging, Biomarker discovery, Bio-Technology, Detection, Molecule recognition
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools