Search Results - tissue+repair

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Composite Gels and Methods of their Use in Tissue Repair, Drug Delivery, and as Implants
Abstract: Gel materials, particularly hydrogels, typically lose their mechanical strength and stiffness as they swell. This property  limits their use in both biological (e.g., cartilage and ECM repair) and non-biological (e.g., sealant) applications. Innovative materials in both medical and non-medical application areas are sorely needed. Recent innovations...
Published: 4/8/2024   |   Inventor(s): Ferenc Horkay, Peter Basser
Keywords(s): Basser, Cartilage, Composite, Drug Delivery, Gel, Horkay, Hydrogels, IMPLANTS, MATRIX, polymer, sealants, Tissue, Tissue Repair
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Materials Available, TherapeuticArea > Dermatology
Microfluidic Method for Continuous Production of Microfibers With Embedded Droplets
Microfluidic Method for Continuous Production of Microfibers with Embedded Droplets Princeton Docket #14-2982 Fibers are a useful medium for numerous applications, including drug delivery. Current technologies usually make fibers of homogeneous chemical composition or employ axial core-shell structures. To create more complex shapes and compositions,...
Published: 3/30/2022   |   Inventor(s): Howard Stone, Janine Nunes, Eujin Um, Tamara Pico
Keywords(s): drug delivery, life science research tools, regenerative medicine, research tool, soft scaffolds, therapeutic, tissue engineering, tissue repair, wound healing
Category(s): Medical Devices/Diagnostics
Magnetically-Responsive Gradient Electrospun Fiberous Materials
Tissue engineering as a means for musculoskeletal damage repair is an ever-growing field. One of the challenges in this tissue engineering is effective interfacial tissue engineering –interfacing between musculoskeletal tissues such as connections from muscle to tendon and ligament to bone. Such interfacing requires gradients in structure, chemical...
Published: 2/23/2023   |   Inventor(s): Julianne Holloway, Kevin Tindell, Fallon Fumasi
Keywords(s): Bio-Technology, Materials and Electronics, Mechanical and Manufacturing, Therapeutics, Tissue Repair
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Genomic Assays/Reagents/Tools
Injectable Microengineered Tissues for Cardiac Regeneration
Each year, millions of patients, globally, suffer from heart failure and cardiovascular disease. Stem cell transplantation and tissue engineering strategies have tremendous potential for repair and/or regeneration of injured myocardium. The major hurdles in stem cell transplantation are poor cell survival, insufficient cardiogenic differentiation,...
Published: 2/23/2023   |   Inventor(s): Mehdi Nikkhah, Brent Vernon
Keywords(s): Biological Cell Manipulation, Cell Culture, MEMS, Tissue, Tissue Repair
Category(s): Life Science (All LS Techs), Biomaterials, Advanced Materials/Nanotechnology, Non-Cancer Therapeutics
Creation of Multi-Functional Hybrid Devices/Structures by Three Dimensional Integration of Individual Components Using 3D Printing
Creation of Multi-functional Hybrid Devices/Structures by Three Dimensional Integration of Individual Components using 3D Printing Princeton Docket 13-2861-1 Researchers at Princeton University have developed a novel process to provide three dimensional manufacturing of object containing various functionalities including light emitting diodes, transistors,...
Published: 7/8/2024   |   Inventor(s): Michael McAlpine, Manu Mannoor, Blake Johnson, Yong Lin Kong
Keywords(s): materials, tissue engineering, tissue repair
Category(s): Medical Devices/Diagnostics, Mechanical/Electrical Engineering, Materials
Smart Scaffolds for Tissue Repair and Regenerative Medicine
Smart Scaffolds for Tissue Repair and Regenerative Medicine Princeton Docket # 12-2742 A major challenge in biomedical research with application to regenerative medicine is to cause cells to assemble into particular orientations or alignments on a scaffold device in order to generate tissues with the required cellular organization and mechanical properties....
Published: 3/30/2022   |   Inventor(s): Jeffrey Schwartz, Jean Schwarzbauer, Casey Jones, Patrick Donnelly, Stephen Bandini
Keywords(s): medical device, soft scaffolds, tissue engineering, tissue repair, wound healing
Category(s): Medical Devices/Diagnostics, Biotechnology/Pharmaceuticals, Materials