Search Results - platforms+%3e+drug+delivery

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Pancreas Cancer Immunotherapy using Cationic Lipid and Polymer Nanocarriers for co-delivery of KRAS Neoantigens and STING or other immunomodulators to boost the Cancer Immunity Cycle and Treat Liver Metastasis (UCLA Case No. 2024-076)
UCLA researchers have developed a translational immunotherapy platform that leverages nanoparticle-based delivery of tumor-associated signals and immune-stimulatory molecules to drive localized immune activation in metastatic pancreatic cancer. This approach is designed to initiate de novo immune priming and recondition the tumor microenvironment in...
Published: 10/29/2025   |   Inventor(s): Andre Nel
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Vaccines, Platforms > Drug Delivery
Mucus Targeting Particles (MTPs) Technology for Sustained Drug Delivery Applications (UCLA Case No. 2020-809)
UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a robust nanoparticle technology for effective, sustained-release ocular drug delivery. BACKGROUND: Topically applied therapeutics are the common mode of delivery for treating ocular diseases, ranging from chronic conditions like glaucoma to acute inflammation...
Published: 10/24/2025   |   Inventor(s): Nasim Annabi, Shima Gholizadeh, Reza Dana
Keywords(s):  
Category(s): Therapeutics > Ophthalmology, Materials > Nanotechnology, Platforms > Drug Delivery
Synthetic Cannabinoid WIN 55,212-2 Increased the Cytotoxicity of NK Cells and IFN-gamma Secretion Ability of Immune Cells in Humanized BLT Mouse Model (UCLA Case No. 2022-281)
UCLA researchers in the School of Dentistry have developed novel strategies synergizing the anti-tumor effects of a synthetic cannabinoid, cytokine, and probiotic bacteria to augments NK cell mediated functions and target a wide variety of cancers and viral infections. BACKGROUND: Interest in the use of synthetic cannabinoids for the treatment of disease...
Published: 10/23/2025   |   Inventor(s): Anahid Jewett
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > Oncology > Oncology Immunotherapy
A Glucose-Responsive Glucagon-Micelle for the Prevention of Hypoglycemia (UCLA Case No. 2024-161)
Contact UCLA Technology Development Group to learn more. More information available soon. Keywords: drug delivery, nanomedicine, nanocarriers, Polymeric Micelles
Published: 10/2/2025   |   Inventor(s): Heather Maynard
Keywords(s):  
Category(s): Platforms > Drug Delivery
Method of Creating Hydrogels Through Oxime Bond Formation (UCLA Case No. 2013-180)
UCLA researchers led by Professor Heather Maynard in the Department of Chemistry have developed a method for creating hydrogels using a patented and specific type of chemical reaction called oxime bond formation (or oxime ligation). BACKGROUND: While many methods exist to create hydrogels (cross-linked materials used in biomedicine), most suffer from...
Published: 10/2/2025   |   Inventor(s): Heather Maynard, Tatiana Segura, Gregory Grover, Jonathan Lam
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > Oncology, Chemical > Polymers
Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)
Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...
Published: 10/1/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun
Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery
Glucagon Conjugated Trehalose Diblock Copolymers and Methods of Use (UCLA Case No. 2024-283)
Contact UCLA Technology Development Group for more information.
Published: 11/20/2025   |   Inventor(s): Heather Maynard
Keywords(s):  
Category(s): Platforms > Drug Delivery, Chemical > Polymers
Discrete Approximation of Permanent Magnet Arrays (Case No. 2025-203)
Summary UCLA researchers have developed Discrete-MAG, a discrete magnetic actuation / magnetics platform that delivers precise, programmable magnetic field manipulation at small scales. The system aims to control magnetic particles or micro-devices discretely for applications in sensing, actuation, imaging, or biological interfacing. Background Magnetic...
Published: 11/5/2025   |   Inventor(s): Tyler Clites, He Kai Lim, Will Flanagan, Cameron Taylor
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Medical Devices, Mechanical, Mechanical > Robotics, Platforms, Platforms > Drug Delivery, Medical Devices > Medical Imaging, Life Science Research Tools, Life Science Research Tools > Research Methods
Self-Assembling Tetrahedral Protein Cages Based on Machine Learning Algorithms (UCLA Case No. 2023-300)
Please contact our office for more information regarding this innovation. See also Technology -2020-922 A Universal Designed Protein Cage for Sensing and Responding to Any Other Protein Molecule Related publications (by the inventors only): Gladkov N, Scott EA, Meador K, Lee EJ, Laganowsky AD, Yeates TO, Castells-Graells R. Design of a symmetry-broken...
Published: 9/12/2025   |   Inventor(s): Todd Yeates
Keywords(s):  
Category(s): Medical Devices, Platforms > Drug Delivery
Designing a Prolonged Method of Therapeutic Delivery to Support Rehabilitation From Ototoxic Damage in a Schwann Cell Model (UCLA Case No. 2023-277)
Please contact our office for information about this hearing loss innovation from UCLA Head and Neck Surgery researchers. Related Publications (from inventors only): Hong MK, Echanique KA, Hoffman LF, Kita AE. Designing a Prolonged Method of Therapeutic Delivery to Support Rehabilitation From Ototoxic Damage in a Schwann Cell Model. Otol Neurotol....
Published: 9/12/2025   |   Inventor(s): Ashley Kita, Larry Hoffman
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > CNS and Neurology
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