Search Results - platforms+%3e+drug+delivery

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Compound Drug Delivery System (Case No. 2024-015)
Summary: Researchers in UCLA’s Department of Orthopaedic Surgery have developed novel multi-drug delivery system that is compatible with standard syringe-based administration routes. Background: Drug compounding is the process of combining two or more medications to meet the needs of individual patients. Surgeons may mix different anesthetics...
Published: 9/11/2024   |   Inventor(s): Fabrizio Billi, Mauricio Silva, Aaron Kavanaugh
Keywords(s):  
Category(s): Therapeutics, Platforms, Platforms > Drug Delivery, Medical Devices
A Bistable Deformable Tactile Responsive Material and Device (Case No. 2024-202)
Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel electroactive polymer membrane composition for interactive tactile interfaces. Background: Interactive tactile interfaces are soft actuators with diverse applications in medical and surgical training, actively deformable apparel, refreshable Braille...
Published: 9/23/2024   |   Inventor(s): Qibing Pei, Jinsung Kim, HyeonJi Hong
Keywords(s): bistable electroactive polymer, Braille, BSEP, deformable geometries, diaphragms, elastomers, hybrid electrodes, joule heating, MCRB, multi-cell refreshable Braille, phase change materials, shape memory, soft actuator, Stretchable electrodes
Category(s): Materials, Materials > Functional Materials, Medical Devices, Platforms, Platforms > Drug Delivery
Discovering Permanent Fluidic Magnets for Liquid Bioelectronics (Case No. 2024-083)
Summary: UCLA researchers from the Department of Bioengineering have developed a permanent fluidic magnet that maintains stable colloids for application in a variety of fields, including physiological monitoring and bioelectronics. Background: Colloid suspensions are comprised of dispersed small solid particles in fluids. The stability of a colloid...
Published: 9/10/2024   |   Inventor(s): Jun Chen
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Mems, Materials > Nanotechnology, Platforms, Platforms > Drug Delivery
Targeted Delivery of IFN-gamma Using Antibody Fusion Proteins (UCLA Case No. 2017-543)
UCLA researchers in the Departments of Microbiology, Immunology & Molecular Genetics (MIMG) and Medicine have developed antibody–cytokine fusion proteins that enable the targeted delivery of active interferon-gamma (IFNγ) for cancer treatment. Interferon-gamma (IFNγ), a type II interferon, is a cytokine released by both natural...
Published: 2/26/2024   |   Inventor(s): Sherie Morrison, John Timmerman, Kham (Ryan) Trinh
Keywords(s): Antibody Delivery Platforms, Drug Delivery, Immunotherapy, Life Science Research Tools, Therapeutics & Vaccines
Category(s): Therapeutics, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Life Science Research Tools, Therapeutics > Immunology And Immunotherapy
Intelligent Stent System for Chronic On-Demand Drug Delivery (Case No. 2021-069)
Summary: UCLA researchers in the Department of Neurology have developed an intelligent stent system for chronic on-demand drug delivery, addressing the challenge of the blood-brain barrier hindering drug therapy in the central nervous system. Background: The blood-brain barrier poses a significant obstacle to effective drug delivery to the central...
Published: 7/9/2024   |   Inventor(s): Jose Morales, Haotian Lu, Huachen Cui, Xiaoyu (Rayne) Zheng
Keywords(s): blood flow management, blood-brain barrier, Drug, Drug Delivery, Drug monitoring, Invasiveness Of Surgical Procedures, MEMS, minimally invasive device, minimally invasive drug delivery systems, neural signals, neural stimulation, Neurocognitive, Neurodegeneration, neurological disorders, Neurology, neuro-oncology, Neuropathology, Neurosurgery, non-invasive, non-invasive drug monitoring, on-demand drug delivery, Pharmaceutical Drug, piezoelectric ultrasound transducers
Category(s): Platforms, Platforms > Drug Delivery, Medical Devices, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Oncology, Therapeutics > Musculoskeletal Disease
2022-165 Development of a Silicasome Drug Nanocarrier System to Deliver a Lipid Bilayer-Encapsulated TLR7 Agonist for Cancer Immunotherapy
SUMMARY: UCLA researchers in the Department of Medicine have developed a scalable and injectable drug delivery platform that allows for tumor-specific combinatorial cancer immunotherapy treatment of pancreatic cancer. BACKGROUND: The National Institute of Health reports that pancreatic ductal adenocarcinomas (PDAC) accounts for at least 90% of all...
Published: 7/19/2023   |   Inventor(s): Andre Nel
Keywords(s):  
Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles, Therapeutics > Oncology
2022-223 A Bioanalytics-Enabled and Hollow Microneedle-Based Wearable Technology for Personalized Medicine
­Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a minimally-invasive wearable device that continuously monitors pharmaceutical concentrations in a user to optimize the drug’s dosage. Background: The annual cost of medication-related morbidity and mortality due to non-optimized pharmacotherapy...
Published: 7/19/2023   |   Inventor(s): Sam Emaminejad, Shuyu Lin
Keywords(s): Adverse Drug Reaction, Antibody-Drug Conjugate, Antiviral Drug, Biomonitoring, Blood Glucose Monitoring, Drug, Drug Carrier, Drug Delivery, Drug Delivery Microporous Material, Drug Development, Drug Development Feature Extraction, Drug Discovery, Drug monitoring, Drug Resistance, Drug-Eluting Stent, Extensively Drug-Resistant Tuberculosis, Fine-Needle Aspiration, Gene Combination Drug, Immunosuppressive Drug, interstitial fluid (ISF)-based information, Investigatioal New Drug, Management Of HIV/AIDS Psychoactive Drug, medical automation technology, Medical Device, Medical Devices and Materials, medication customization, medication efficacy, Microneedle array, minimally invasive device, Monitoring (Medicine), Monitoring And Recording Systems, Multiple Drug Resistance, Mutation Drug Design, Nanosensor, Nanostructure, Nanotechnology, non-invasive drug monitoring, personalized dose assessment, Pharmaceutical Drug, Pharmaceutical Drug Ethylene Glycol, Pharmaceutical Drug Opioid Dependence, Prescription Drug, real-time sensing/monitoring/tracking, remote monitoring, sample-to-answer devices, Smart medical device, Therapeutic Drug Monitoring, wearable medical device
Category(s): Mechanical, Mechanical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Drug Delivery, Software & Algorithms > Bioinformatics, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical > Sensors, Materials > Nanotechnology
2020-922 A Universal Designed Protein Cage for Sensing and Responding to Any Other Protein Molecule
SUMMARY: UCLA researchers in the Department of Chemistry and Biochemistry have designed and developed a protein cage which can be easily tailored to sense other proteins, opening in response, and thus delivering enclosed biological compounds across a wide variety of applications, including biosensing, molecular diagnostics, and targeted drug delivery....
Published: 9/5/2023   |   Inventor(s): Todd Yeates
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Drug Delivery
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Drug Delivery, Platforms > Drug Delivery > Nucleic Acid Platform Systems, Platforms > Drug Delivery > Nanoparticles, Platforms > Drug Delivery > Nucleic Acids
Novel Vaginal Drug Delivery Device (UCLA Case No. 2020-444)
Summary: UCLA researchers in the Departments of Biomedical Engineering and Medicine have developed vaginal drug delivery devices for the administration of contraceptives and antibiotics. Background: Globally, 1.9 billion women of reproductive age (15-49 years) use contraceptives. An additional 190 million women would use phrophylactics/contraceptives...
Published: 8/7/2024   |   Inventor(s): Leena Nathan, Song Li, Tamara Grisales, Mohammad Hasani-Sadrabadi
Keywords(s):  
Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Platforms > Drug Delivery > Other Polymers
Optimized Lentiviral Vector for Stem Cell Gene Therapy of Hemoglobinopathies
UCLA Case No. 2017-460 Summary UCLA researchers in the Department of Microbiology, Immunology and Molecular Genetics have developed a novel method to produce short lentiviral vectors with tissue-specific expression, with a primary focus on lentiviral vectors for treating sickle cell disease and other disorders of hemoglobin. Background Sickle...
Published: 1/23/2024   |   Inventor(s): Donald Kohn, Roger Hollis, Richard Morgan
Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Genetic Disease, Life Science Research Tools, Plasmids / Vectors, Research Methods, Therapeutics & Vaccines, Viral Delivery Systems
Category(s): Life Science Research Tools > Plasmids/Vectors, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms > Drug Delivery, Therapeutics, Platforms > Drug Delivery > Viral Delivery Systems, Therapeutics > Gene Therapy And Editing
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