Search Results - platforms+%3e+drug+delivery

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A Glucose-Responsive Glucagon-Micelle for the Prevention of Hypoglycemia (UCLA Case No. 2024-161)
Contact UCLA Technology Development Group to learn more. More information available soon. Keywords: drug delivery, nanomedicine, nanocarriers, Polymeric Micelles
Published: 10/2/2025   |   Inventor(s): Heather Maynard
Keywords(s):  
Category(s): Platforms > Drug Delivery
Method of Creating Hydrogels Through Oxime Bond Formation (UCLA Case No. 2013-180)
UCLA researchers led by Professor Heather Maynard in the Department of Chemistry have developed a method for creating hydrogels using a patented and specific type of chemical reaction called oxime bond formation (or oxime ligation). BACKGROUND: While many methods exist to create hydrogels (cross-linked materials used in biomedicine), most suffer from...
Published: 10/2/2025   |   Inventor(s): Heather Maynard, Tatiana Segura, Gregory Grover, Jonathan Lam
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > Oncology, Chemical > Polymers
Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)
Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...
Published: 10/1/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun
Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery
Glucagon Conjugated Trehalose Diblock Copolymers and Methods of Use (UCLA Case No. 2024-283)
Contact UCLA Technology Development Group for more information.
Published: 9/16/2025   |   Inventor(s): Heather Maynard
Keywords(s):  
Category(s): Platforms > Drug Delivery, Chemical > Polymers
Discrete Approximation of Permanent Magnet Arrays (Case No. 2025-203)
Summary UCLA researchers have developed Discrete-MAG, a discrete magnetic actuation / magnetics platform that delivers precise, programmable magnetic field manipulation at small scales. The system aims to control magnetic particles or micro-devices discretely for applications in sensing, actuation, imaging, or biological interfacing. Background Magnetic...
Published: 10/8/2025   |   Inventor(s): Tyler Clites, He Kai Lim, Will Flanagan, Cameron Taylor
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Medical Devices, Mechanical, Mechanical > Robotics, Platforms, Platforms > Drug Delivery, Medical Devices > Medical Imaging, Life Science Research Tools, Life Science Research Tools > Research Methods
Self-Assembling Tetrahedral Protein Cages Based on Machine Learning Algorithms (UCLA Case No. 2023-300)
Please contact our office for more information regarding this innovation. See also Technology -2020-922 A Universal Designed Protein Cage for Sensing and Responding to Any Other Protein Molecule Related publications (by the inventors only): Gladkov N, Scott EA, Meador K, Lee EJ, Laganowsky AD, Yeates TO, Castells-Graells R. Design of a symmetry-broken...
Published: 9/12/2025   |   Inventor(s): Todd Yeates
Keywords(s):  
Category(s): Medical Devices, Platforms > Drug Delivery
Designing a Prolonged Method of Therapeutic Delivery to Support Rehabilitation From Ototoxic Damage in a Schwann Cell Model (UCLA Case No. 2023-277)
Please contact our office for information about this hearing loss innovation from UCLA Head and Neck Surgery researchers. Related Publications (from inventors only): Hong MK, Echanique KA, Hoffman LF, Kita AE. Designing a Prolonged Method of Therapeutic Delivery to Support Rehabilitation From Ototoxic Damage in a Schwann Cell Model. Otol Neurotol....
Published: 9/12/2025   |   Inventor(s): Ashley Kita, Larry Hoffman
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > CNS and Neurology
Inhalational Therapy for Tuberculosis and Mycobacterial Lung Disease (UCLA Case No. 2025-278)
UCLA researchers from the Department of Medicine have identified drug combinations that can speed up treatment of tuberculosis by being delivered intranasally as well as orally. BACKGROUND: Tuberculosis (TB) is an airborne disease caused by the bacterium Mycobacterium tuberculosis, affecting more than 10 million people worldwide each year. The standard...
Published: 8/13/2025   |   Inventor(s): Marcus Horwitz, Bai Yu Clemens, Daniel Clemens
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > Infectious Diseases, Therapeutics > Respiratory And Pulmonary
Subgraph Matching for High-Throughput DNA-Aptamer Secondary Structure Classification and Machine Learning Interpretability (Case No. 2025-104)
Intro Sentence: UCLA researchers in the Department of Mathematics have developed machine learning methods to rapidly identify novel aptamer sequences for target binding to accelerate highly-accurate diagnostic and therapeutic development. Background: Aptamers are single-stranded nucleotide polymers that bind with high affinity to targets such as...
Published: 8/19/2025   |   Inventor(s): Andrea Bertozzi, Anne Andrews, Matthew Tyler, Paolo Climaco, Noelle Mitchell
Keywords(s): Advanced Computing / AI, advanced computing methods, Aptamers, Artifical Intelligence (Machine Learning, Data Mining), artificial intelligence/machine learning models, bioinformatics pipeline, cancer target, clustering, computational efficiency, computational efficiency and analysis, design software, DNA clustering, DNA oligomer, DNA Sequencing, Drug, Drug Delivery, Drug Development, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, interpretability, pipeline, large-scale parallelization, Machine Learning, machine learning modeling, motif structures, open source, open source code, OpenAI, Pharmaceutical Drug, protein classification, secondary structure, SELEX, sequences of interest, single strand DNA sequences, Software, Software & Algorithms, Software Development Tools, Software-enabled learning, subgraph matching, target binding, target detection, Targeted Therapy, Targets And Assays, tissue targeting accuracy
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Data Analytics, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Screening Libraries, Platforms, Platforms > Drug Delivery, Diagnostic Markers > Targets And Assays, Diagnostic Markers, Software & Algorithms > Bioinformatics
Modified Hyaluronic Acid Hydrogels Containing Hyaluronidase for the Time‐Controlled and Targeted Release of anti-CTLA-4 and other Therapeutic Antibodies (UCLA Case No. 2016-526)
UCLA researchers from the Department of Medicine have developed a novel therapeutic platform for the administration of low-dose Cytotoxic T-lymphocyte Associated Protein 4 (CTLA-4) antibody for cancer immunotherapy that synergizes with conventional PD-1 therapy while sparing systemic autoimmune toxicity. BACKGROUND: Immune checkpoint inhibitor (CPI)...
Published: 7/17/2025   |   Inventor(s): Michael Roth, Airi Harui
Keywords(s): Cancer Immunotherapy, Immunotherapy
Category(s): Platforms > Drug Delivery, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology
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