Search Results - yvonne+kapila

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Nisin Lantibiotic Mitigates Brain Microbiome Dysbiosis and Alzheimer’s Disease-Like Neuroinflammation (UCLA Case No. 2024-096)
Researchers led by Professor Yvonne Kapila in the UCLA School of Dentistry have developed a technology that harnesses nisin, a well-characterized probiotic lantibiotic bacteriocin, as a novel therapeutic to address brain microbiome dysbiosis and Alzheimer’s disease (AD)-like neuroinflammation driven by periodontal disease. By targeting the microbial...
Published: 9/13/2025   |   Inventor(s): Yvonne Kapila
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology
Nisin-Based Formulations for Oral and Systemic Conditions (UCLA Case Nos. 2023-133 and 2022-306)
UCLA researchers in the Department of Dentistry have found a novel use for nisin alone, and in formulations, for use in the treatment of Alzheimer’s disease, and multiple inflammation states such as brain inflammation, joint inflammation, oral inflammation, systemic inflammation, inflammatory bowel diseases, and non-alcoholic fatty liver disease...
Published: 7/17/2025   |   Inventor(s): Yvonne Kapila
Keywords(s): Alzheimers disease, Antibacterial, gut inflammation, Inflammation, microbiome, nanoparticle delivery system, Nanoparticles, nisin, oral inflammation, periodontal disease, periodontal inflammation, periodontal regeneration
Category(s): Therapeutics > CNS and Neurology