Search Results - obesity+metabolic+disease+and+diabetes

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Space Shuttle-Inspired Branched Lipid Nanoparticles As Potent mRNA Transporters
Lipid nanoparticles (LNPs) with reversibly attached branched lipid tails for the delivery of mRNA for gene therapy. Problem: Delivery of mRNA to target cells enables the expression of engineered proteins but mRNA is unstable and negatively charged, necessitating a delivery vehicle to ensure its entry into cells. LNPs can ferry mRNA across the cell...
Published: 11/26/2024   |   Inventor(s): Michael Mitchell, Xuexiang Han
Keywords(s): Bioengineering, Drug Delivery, Gene Therapy, Nanotechnology, Obesity Metabolic Disease and Diabetes, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics
Physiology-independent control algorithm for an artificial pancreas
An insulin pump control system that works automatically without user input Problem: Diabetic patients can use insulin pumps to deliver insulin after a meal. Continuous glucose monitoring (CGM) systems are also used to record glucose levels throughout the day. These systems could be unified via a closed-loop control algorithm to create an artificial...
Published: 1/17/2025   |   Inventor(s): Insup Lee
Keywords(s): Drug Delivery, Obesity Metabolic Disease and Diabetes
Category(s): Technology Classifications > Medical Devices