Search Results - protein+sequencing

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Nanopore and membrane protein dynamic multichannel measurement apparatus and fabrication method for same
INV-23089 Background: Nanopore sensing devices are integral to scientific research and applications such as DNA sequencing and protein detection. The dynamic of trans and cis user access to a membrane in such devices can, however, pose significant challenges. Fulfilling the need for multiplexed and scalable nanopore sensing systems, especially those...
Published: 9/10/2024   |   Inventor(s): Meni Wanunu, Ali Fallahi, Amr Makhamreh
Keywords(s): Biosensing, Drug Discovery, Microfluidics, Nanopores, Protein sequencing
Category(s): Technology Classifications > 2. Physical Science, Technology Classifications > 1. Life Science > Gene sequencing, Technology Classifications > 1. Life Science, Diagnostics
Linearization and Translocation of Single Protein Molecules Through Biological Nanopores
INV-21060 Background Nanopore sensing is a promising technology that detects and sequences biomacromolecules without depending on biomolecule modification, labeling, or surface immobilization. Rapid detection of biomacromolecules revolutionizes the field of proteomics and disease diagnosis. Nanopore technology employs nanoscale pores between two electrolytic...
Published: 9/10/2024   |   Inventor(s): Meni Wanunu, Luning Yu, Aleksei Aksimentiev, Behzad Mehrafrooz
Keywords(s): Protein sequencing
Category(s): -Biomedical Materials, -Nanotechnology, -Materials, Technology Classifications > 1. Life Science
High-Resolution Sensor of Biopolymer Sequence and Molecules Based on a Localized Nanopore Electrode Sequencer (LNES)
INV-19043 Background This technology introduces two approaches to polymer sequencing using nanopores in electrically conducting, ion‐intercalating MXene membranes, split into two applications: - The first application of MXene membranes is based on ion transport localization between an ultrathin nanopore composed of intercalated ions (between MXene...
Published: 9/10/2024   |   Inventor(s): Meni Wanunu, Mehrnaz Mojtabavi, Armin Vahid Mohammadi, Majid Beidaghi
Keywords(s): DNA sequencing, Nanopores, Protein sequencing, RNA sequencing, Single-molecule mapping
Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering