Search Results - metabolic+disorders

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Small molecule inhibits the interaction between tristetraprolin and CNOT1 for therapeutic use in metabolic disorders
NU 2024-057 INVENTORS Hossein Ardehali* Jason Shapiro SHORT DESCRIPTION Compound that inhibits the interaction between tristetraprolin (TTP) and CCR4-NOT Transcription Complex Subunit 1 (CNOT1) offers potential therapeutic avenue for metabolic disorders by modulating mRNA degradation without inflammatory side effects. BACKGROUND Metabolic disorders...
Published: 3/26/2026   |   Updated: 5/5/2025   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, Diabetes, Metabolic disorders, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
Methylene Blue and Methylene Violet Analogs as Mitochondrial Therapeutic Agents
Mitochondrial dysfunction has been implicated in a number of diseases, including Alzheimer’s disease (AD), movement disorders, diseases of the cardiovascular system, cancer, diabetes, blindness and deafness. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Membrane-penetrating...
Published: 2/26/2026   |   Updated: 12/27/2023   |   Inventor(s): Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Nishant Visavadiya
Keywords(s): Alzheimer's Disease, Diabetes, Genetic Disorders, Metabolic Disorders, Mitochondrial medicine
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Methylene Blue and Methylene Violet Analogs as Mitochondrial Therapeutic Agents
Mitochondrial dysfunction has been implicated in a number of diseases, including Alzheimer’s disease (AD), movement disorders, diseases of the cardiovascular system, cancer, diabetes, blindness and deafness. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Membrane-penetrating...
Published: 2/26/2026   |   Updated: 12/27/2023   |   Inventor(s): Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Indrajit Bandyopadhyay
Keywords(s): Alzheimer's Disease, Diabetes, Genetic Disorders, Metabolic Disorders, Mitochondrial medicine, Neurodegenerative Disorders, Parkinson's Disease, Pharmaceutical
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
Antibodies Against Transcription Factors BMAL1 and CLOCK for the Study of Metabolic Disease
NU 2015-059INVENTORSJoseph T. Bass*Clara Bien PeekGrant D. Barish SHORT DESCRIPTIONAntibodies targeting transcription factors, BMAL1 and CLOCK, to study the regulation of circadian expression of proteins related to metabolic diseaseBACKGROUNDMetabolic diseases such as diabetes, obesity, and related diseases such as inflammation and cancer affect millions...
Published: 3/19/2026   |   Updated: 4/24/2020   |   Inventor(s):  
Keywords(s): Antibody, Diabetes, Metabolic disorders, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools