Search Results - cardiology+and+cardiovascular+disease

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Transparent Arterial Layer Separation in Cardiac Angiography with Self-Supervised Deep Learning
NU 2023-092 INVENTORS Sameer Ansari* Donald Cantrell* Leon Cho Syed Hasib Akhter Faruqui Chaochao Zhou SHORT DESCRIPTION This technology provides cardiac angiography with markedly enhanced visualization of the vasculature by leveraging self-supervised deep neural network-based background subtraction algorithms. BACKGROUND Cardiac angiography relies...
Published: 5/12/2025   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, Image/Signal processing
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Wireless, Implantable Catheter-type Oximeter Designed for Cardiac Oxygen Saturation
LUNU 2020-226 INVENTORS John Rogers* Wei Lu Joseph Forbess Zhi-Dong Ge SHORT DESCRIPTION This technology introduces a wireless, miniaturized, implantable catheter-type oximeter designed to offer real-time monitoring of intravascular oxygen levels for post-cardiothoracic surgery care. BACKGROUND Accurate, real-time monitoring of intravascular oxygen...
Published: 5/7/2025   |   Inventor(s):  
Keywords(s): Biomedical, Cardiology and Cardiovascular disease, Devices, Diagnostics, Medical device, Optics, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Small molecule inhibits the interaction between tristetraprolin and CNOT1 for therapeutic use in metabolic disorders
NU 2024-057 INVENTORS Hossein Ardehali* Jason Shapiro SHORT DESCRIPTION Compound that inhibits the interaction between tristetraprolin (TTP) and CCR4-NOT Transcription Complex Subunit 1 (CNOT1) offers potential therapeutic avenue for metabolic disorders by modulating mRNA degradation without inflammatory side effects. BACKGROUND Metabolic disorders...
Published: 5/5/2025   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, Diabetes, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
Personalized chest acceleration derived prediction of cardiovascular abnormalities using deep learning
Personalized chest acceleration derived prediction of cardiovascular abnormailities using deep learning NU 2023-121 INVENTORS Michael Markl * Ethan M.I. Johnson Mahmoud Ebrahimkhani SHORT DESCRIPTION A system and method for predicting cardiovascular function using machine learning from physiological patient data. BACKGROUND Cardiac and flow...
Published: 5/20/2025   |   Inventor(s):  
Keywords(s): Artificial Intelligence & Machine Learning, Cardiology and Cardiovascular disease, Computer hardware, Devices, Diagnostics, Imaging, Mobile networking, Networking
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Maskless 2D/3D Artificial Subtraction Angiography
LUNU2019-160 INVENTORS Sameer Ansari* Donald Cantrell* SHORT DESCRIPTION This invention leverages machine learning to enhance angiographic imaging by removing bone and soft tissue interference without a pre-injection digital mask, providing improved visualization of vasculature in real-time and accommodating patient motion. BACKGROUND Conventional...
Published: 4/23/2025   |   Inventor(s):  
Keywords(s): Artificial Intelligence & Machine Learning, Cardiology and Cardiovascular disease, Imaging
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Myocardial Scar Burden Signatures for Simultaneously Assessing Scar Extent and Distribution from Imaging Data
NU 2023-063 INVENTORS Mohammed Elbaz* SHORT DESCRIPTION This technology introduces a novel method for quantifying myocardial scar burden by leveraging imaging data to simultaneously assess scar extent and distribution, facilitating enhanced diagnosis and management of heart diseases. BACKGROUND Myocardial infarction (MI) is a fatal heart disease...
Published: 4/23/2025   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, Image/Signal processing, Imaging
Category(s): Life Sciences > Healthcare Devices, Tools & IT
A microneedle-patterned polymer coating for next-generation drug-coated balloon catheters
NU 2024-188 Inventors Bowen Wang* Guojun Chen Short Description Next generation drug-coated balloon catheter using a microneedle-patterned polymer coating to penetrate deep into vessel walls and deliver a variety of payloads. Background Balloon angioplasty remains the standard of care for occlusive cardiovascular diseases, yet its...
Published: 4/23/2025   |   Inventor(s):  
Keywords(s): Biomedical, Cardiology and Cardiovascular disease, Healthcare, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
New Targets and Methods for Treating Pulmonary Hypertension and Cardiomyopathy
LU 2020-120, LU 2021-119, LU 2021-191 INVENTOR Youyang Zhao* SHORT DESCRIPTION New targets and methods for treating pulmonary hypertension, cardiomyopathy, and heart failure. BACKGROUND Pulmonary hypertension (PH) and cardiomyopathy are deleterious diseases often characterized by excessive vasoconstriction or abnormal vascular-ventricular...
Published: 4/23/2025   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Cardiology and Cardiovascular disease, Pulmonary disease, Therapeutics
Category(s): Life Sciences > Therapeutics
Novel Approach to Attenuate Anthracycline-Induced Cardiotoxicity due to Doxorubicin
NU 2018-028 INVENTORS Paul Burridge* Tarek Magdy SHORT DESCRIPTION The use of desipramine to protect against doxorubicine-induced cardiotoxitiy BACKGROUND Doxorubicin, a cytotoxic anthracycline antibiotic, is a common anti–cancer agent used to treat a wide variety of adult and childhood cancers. The cardiotoxicity of anthracyclines, however,...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Cardiology and Cardiovascular disease, Therapeutics
Category(s): Life Sciences > Therapeutics
A Terlipressin-Albumin Conjugate for Increased Stability
NU2018-179 INVENTORS Nathan Gianneschi* Or Berger Wonmin Choi SHORT DESCRIPTION A new compound consisting of terlipressin coupled to an 18-carbon (C-18) fatty acid that allows the drug to bind to albumin, providing increased stability. BACKGROUND Terlipressin, an analogue of vasopressin, is used in many countries around the world to treat a variety...
Published: 3/3/2025   |   Inventor(s):  
Keywords(s): Cardiology and Cardiovascular disease, Drug delivery, Therapeutics
Category(s): Life Sciences > Therapeutics
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