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Search Results - pingbo+zhang
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Conditional FKBP51 Over-expression Transgenic Mouse
Advantages: Created a transgenic mice model that allows researchers to precisely control the expression of human FKBP51. Offers a tailored approach to studying psychiatric disorders, enabling the development of personalized treatments. Enhances the understanding of the molecular mechanisms underlying psychiatric disorders such as depression,...
Published: 9/3/2024
|
Inventor(s):
Chad Dickey(VA) (DECEASED - See Notes)
,
Laura Blair
,
Bo Zhang
Keywords(s):
Animal Models
,
Psychiatry / Mental Health
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Therapeutics
Novel Human Insulin Cα-Peptide as an Antagonist for Islet and Brain Amyloidosis
Abstract: Over 32 million Americans are living with Diabetes and newly diagnosed cases of type 1 and type 2 diabetes is increasing. A defining feature of type 2 diabetes mellitus (T2DM) is the accumulation of islet amyloid polypeptide (IAPP) fibrils in pancreatic islets. Such accumulations form amyloid plaques, referred to as islet amyloidosis. Mounting...
Published: 4/8/2024
|
Inventor(s):
Qing Rong Liu
,
Min Zhu
,
Pingbo Zhang
,
Josephine Egan
,
Luigi Ferrucci
Keywords(s):
Alzheimer’s Disease
,
Amyloidosis
,
C-peptide
,
DIABETES
,
Egan
,
insulin
,
Islet Amyloid Polypeptide
,
Liu
,
National Institute on Aging
,
NIA
Category(s):
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
,
Application > Therapeutics
,
TherapeuticArea > Endocrinology
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
|
Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Medical Imaging
,
Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Programmable In-Memory Computing Accelerator for Low-Precision Deep Neural Network Inference
Background In the era of artificial intelligence, various deep neural networks (DNNs), such as multi-layer perceptron, convolutional neural networks, and recurrent neural networks, have emerged and achieved human-level performance in many recognition tasks. These DNNs usually require billions of multiply-and-accumulate (MAC) operations, soliciting...
Published: 2/23/2023
|
Inventor(s):
Jae-Sun Seo
,
Shihui Yin
,
Mingoo Seok
,
Bo Zhang
Keywords(s):
Artificial Intelligence
,
Circuits
,
Computational Machine
,
Electronics
,
Machine Learning
Category(s):
Physical Science
,
Computing & Information Technology
,
Intelligence & Security