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Search Results - wenqing+li
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Microneedle array coating technology for enhanced stability and targeted delivery of mRNA and biologics
A microneedle-based system uses cryogenically pre-cooled needles coated via thin-film freeze-coating to preserve mRNA stability, enabling efficient, multi-therapeutic intradermal delivery of temperature-sensitive drugs. Background The field of advanced drug delivery systems has grown substantially as the biomedical industry grapples with the complexities...
Published: 1/27/2026
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Inventor(s):
Zhengrong Cui
,
Michael Sandoval
,
Robert Williams
,
Drew Weissman
,
Qin Li
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug discovery
Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025
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Inventor(s):
Li Li
,
Shichao Wu
,
Jiawei Zhao
Keywords(s):
Category(s):
Technology Category > Research tools
,
Technology Category > Animal models
,
Technology Category > Biology
,
Technology Category > Diagnostic
Low-Cost High-Performance 3D LiDAR Imaging System
Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025
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Inventor(s):
Wen Li
,
Suk Kyoung Lee
,
Blessed Oguh
,
Sulaiman Abubakar
Keywords(s):
Category(s):
Technology Category > Automotive & Transportation
,
Technology Category > Physical Sciences
,
Technology Category > Image Analysis (Cameras & Software)
,
Technology Category > Revolutionizing Mobility
Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.
Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...
Published: 5/9/2025
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Inventor(s):
Suraj Sable
,
James Posey
,
Wen Li
,
Allison Kline
Keywords(s):
Category(s):
Application > Therapeutics
,
Application > Research Materials
,
TherapeuticArea > Infectious Disease
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 10/21/2025
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Inventor(s):
Wen Li
,
Hasan Banna
,
James Siegenthaler
,
Mohammad Kafi Kangi
,
Tumi Olason
Keywords(s):
Category(s):
Agriculture
,
Analytical Instruments
,
Environment
,
Test and Measurement
Recovering Critical Elements from Acid Mine Drainage
THE CHALLENGE The demand for certain elements, such as Manganese (Mn), Cobalt (Co), and Nickel (Ni), has surged in recent years due to the rapid growth of battery production for electric vehicles and utility-scale energy storage. The United States government has deemed Co, Ni, and Mn critical elements, primarily because of the country’s high...
Published: 10/17/2025
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Inventor(s):
Wencai Zhang
,
Qi Li
,
Rick Honaker
Keywords(s):
Category(s):
Technology Classifications > Energy
,
Technology Classifications > Mining and Recycling
,
Technology Classifications
,
Technology Classifications > Chemicals/Materials
Peptide Hydrogels for Rate-Controlled Delivery of Therapeutics
Abstract: Hydrogels represent an attractive controlled drug-delivery system that have been used in various clinical applications, such as: tissue engineering for wound healing, surgical procedures, pain management, cardiology, and oncology. High-water content of hydrogels confers tissue-like physical properties and the crosslinked fibrillar network...
Published: 4/22/2025
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Inventor(s):
Joel Schneider
,
Stephen Miller
,
Yuji Yamada
,
Steven Tau
,
Julie Hixon
,
Wenqing Li
,
Caroline Andrews
,
Scott Walsh
Keywords(s):
DEVICE
,
IL-7
,
Nanoparticle
,
Peptide
,
Peptide-based Hydrogel
,
Protein
,
Schneider
,
small molecule
,
T Cell Enhancer
,
Whole Cell Delivery System
Category(s):
TherapeuticArea > Oncology
,
Collaboration Sought > Collaboration
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
,
Collaboration Sought > Licensing
,
TherapeuticArea > Immunology
IL7Rα-Specific Antibody for Treating Acute Lymphoblastic Leukemia (ALL)
Abstract: Acute lymphoblastic leukemia (ALL) is the most common cancer in children with approximately 3,250 new cases occurring per year in the United States. About 20% of cases are refractory to current treatment protocols and there is a desperate need for targeted therapies that do not result in adverse side effects such as cognitive impairment. The...
Published: 4/23/2025
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Inventor(s):
Scott Durum
,
Julie Hixon
,
Wenqing Li
,
Scotch Walsh
,
Lila Kashi
Keywords(s):
Acute lymphoblastic leukemia (ALL)
,
ANTIBODY
,
Antibody-Dependent Cellular Cytotoxicity (ADCC)
,
Autoimmunity
,
CANCER
,
DIABETES
,
Durum
,
Interleukin-7 receptor-α (IL-7Rα)
,
Multiple sclerosis
,
personalized medicine
,
Targeted therapy
,
THERAPY
,
TRANSPLANTATION
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
TherapeuticArea > Oncology
,
Collaboration Sought > Collaboration
Scribble: Optimised Segmentation of Medical Images through AI
Summary: A semi-automated, artificial-intelligence based, interactive method for selecting a structure in a medical image, that requires only limited input from the users. What Segmentation is used extensively in medical imaging to highlight specific structures (e.g. an organ, a blood vessel or a tumour) and locations that should be...
Published: 11/12/2024
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Inventor(s):
Sebastien Ourselin
,
Tom Vercauteren
,
Guotai Wang
,
Wenqi Li
,
Lucas Fidon
Keywords(s):
Category(s):
Software
,
Diagnostics
,
Artificial Intelligence
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
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