Search Results - luiz+bertassoni

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eDentin- a tissue engineered reparative dentin
Summary Current dental restoration materials trigger immune responses and poorly replicate the natural structure of the tooth, which delays the healing process. The current technology is a novel biomaterial that more closely mimics natural dentin and thereby allows for more efficient healing of the tooth. Technology Overview Cement-based materials...
Published: 6/21/2024   |   Inventor(s): Luiz Bertassoni, Cristiane Miranda Franca
Keywords(s): Dental, Device, Device - Other
Category(s): Dental, Device
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
A method to regenerate vascularized dental pulp for root canal dental therapy
Summary Current root canal therapies rely on removing necrotic tissue and filling the area with inert material, reducing vascularity in the dental pulp and overall health in the remaining tooth. The laboratory of Dr. Luiz Bertassoni has developed a novel root canal treatment that features a hydrogel filling with a hollow central chamber, which can...
Published: 1/15/2024   |   Inventor(s): Luiz Bertassoni, Anthony Tahayeri, Avathamsa Athirasala, Jack Ferracane
Keywords(s):  
Category(s): Dental
A photocrosslinkable bone derived biomaterial for tissue engineering applications
Summary Demineralized bone matrix has been widely used in the clinic to heal bone injuries due to its remarkable regenerative properties. However, this is not a material that can be synthesized in large batches, with highly reproducible chemistry, and cannot be set/polymerized in-situ for precise adaptation. BoneMA is photopolymerizable material that...
Published: 7/2/2024   |   Inventor(s): Luiz Bertassoni, Avathamsa Athirasala
Keywords(s):  
Category(s): Therapeutics, Device
"Tooth on a chip"- A microfluidic device to test interactions of biomaterials with dental structures
Summary The development of novel dental biomaterials requires in vitro validation and cytotoxicity studies; however, research platforms that accurately emulate the oral environment, the interface between biomaterials with the tooth, and the underlying dental pulp, do not currently exist. This is traditionally done by exposing plated cells to eluents...
Published: 6/21/2024   |   Inventor(s): Luiz Bertassoni
Keywords(s): Dental, Device, Research Tools - Other
Category(s): Device
A biomimetic mineralizing cell-culture medium
Summary A cell culture medium to control mineralization of extracellular matrix (hydrogels) in 2D and 3D cell cultures in regeneration studies. It allows the organic scaffold or matrix to mineralize over a set period of time in the presence of cells resulting in a structure that is similar to natural mineralized tissue. Technology Overview Bones...
Published: 9/30/2022   |   Inventor(s): Luiz Bertassoni
Keywords(s): Biological Materials, Research Tools
Category(s): Biological Materials, Research Tools
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology