Search Results - vascular+repair

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Methods for Treatment of Sepsis and Acute Respiratory Distress Syndrome
LU2025-192 INVENTORS Youyang Zhao Colin Evans SHORT DESCRIPTION This invention identifies endothelial ALOX15 and its lipid product, 1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol (POLAR), as key targets for treating sepsis and acute respiratory distress syndrome (ARDS). BACKGROUND Sepsis-induced acute lung injury (ALI) and acute...
Published: 12/11/2025   |   Inventor(s):  
Keywords(s): ARDS - Acute Respiratory Distress Syndrome, Lung disease, Sepsis, Therapeutics, Vascular disease, Vascular repair
Category(s): Life Sciences > Therapeutics
AAV Gene Therapy for Complications with Diabetes and Vascular Diseases
AAV Vectors Rely on Tissue-Specific Promoters to Target Vascular Endothelial Cells This AAV gene therapy transduces vascular endothelial cells and targets complications associated with diabetes and other vascular diseases. Available gene therapy vectors do not efficiently or selectively transduce vascular endothelial cells, which are associated with...
Published: 6/27/2021   |   Inventor(s): William Hauswirth, Sanford Boye, Michael Boulton, Shannon Boye, Daniel Lipinski
Keywords(s): AAV, Diabetes, Gene Therapy, hypercholesterolemia, Hypertension, retinal disease, vascular endothelial junctions, Vascular Repair
Category(s): Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Therapeutics