Search Results - vascular+repair

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Drug Repurposing for Age-Impaired Vascular Repair in COVID-19, Sepsis, and ARDS
SHORT DESCRIPTION Methods and compositions for treating COVID-19, sepsis, acute respiratory distress syndrome (ARDS), and cardiovascular diseases in elderly patients by either inhibiting vascular endothelial injury/inflammation or promoting FOXM1-dependent endothelial regeneration and vascular repair. INVENTORS Youyang Zhao Northwestern...
Published: 5/8/2026   |   Updated: 4/22/2026   |   Inventor(s):  
Keywords(s): ARDS - Acute Respiratory Distress Syndrome, COVID-19, Immunology, Infectious disease, Inflammation, Pulmonary disease, Therapeutics, Vascular disease, Vascular repair
Category(s): Life Sciences > Therapeutics
Methods for Treatment of Sepsis and Acute Respiratory Distress Syndrome
LU2025-192 INVENTORS Youyang Zhao Ann & Robert H Lurie Children's Hospital of Chicago Colin Evans SHORT DESCRIPTION This invention identifies endothelial ALOX15 and its lipid product, 1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol (POLAR), as key targets for treating sepsis and acute respiratory distress syndrome...
Published: 5/8/2026   |   Updated: 10/17/2025   |   Inventor(s):  
Keywords(s): ARDS - Acute Respiratory Distress Syndrome, Lung disease, Sepsis, Therapeutics, Vascular disease, Vascular repair
Category(s): Life Sciences > Therapeutics
AAV Gene Therapy for Complications with Diabetes and Vascular Diseases
AAV Vectors Rely on Tissue-Specific Promoters to Target Vascular Endothelial Cells This AAV gene therapy transduces vascular endothelial cells and targets complications associated with diabetes and other vascular diseases. Available gene therapy vectors do not efficiently or selectively transduce vascular endothelial cells, which are associated with...
Published: 1/20/2026   |   Updated: 5/15/2019   |   Inventor(s): Sanford Boye, Michael Boulton, Shannon Boye, Daniel Lipinski, William Hauswirth
Keywords(s): AAV, Diabetes, Gene Therapy, hypercholesterolemia, Hypertension, retinal disease, vascular endothelial junctions, Vascular Repair
Category(s): Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Therapeutics