Search Results - soft+materials

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A Solvent For The Extraction And Preservation Of mRNA At Room Temperature
A buffer that allows the extraction and long-term room temperature preservation of mRNA. Problem: mRNA is unstable in aqueous environments, so different formulations have been explored as water-free solvents for RNA. However, these solvents often contain toxic heavy metals, resulting in biological incompatibility. Additionally, current mRNA vaccines...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Hoang Dinh
Keywords(s): COVID-19, Infectious Disease, Platform Technology, Soft Materials
Category(s): Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Cardiovascular Assist Device Improving Circulation In Patients With Congenital Heart Disease Undergoing The Fontan Procedure
Valveless pump device implanted during the Fontan surgical procedure in patients with single-ventricle congenital heart disease. Problem: The Fontan procedure is a lifesaving surgery for patients with single-ventricle congenital heart disease, where only one chamber of the heart is functional. The operation reroutes blood flow from the heart to the...
Published: 6/4/2026   |   Updated: 6/4/2026   |   Inventor(s): Cynthia Sung, Jordan Raney, Gabriel Unger, Saheli Patel, Benjamin Kozyak
Keywords(s): Bioengineering, Cardiovascular, Pulmonary, Soft Materials, Surgery
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Robotics
LNP-Enabled Intracellular Delivery of Recombinant bioPROTACs
Recombinant fusion bioPROTACs are combined with cationic delivery agents and lipid formulations to enable cytosolic entry and on-demand intracellular degradation of target proteins. Tech Title: Technology: Technology: The core construct is a recombinant fusion protein comprising an E3 ubiquitin ligase domain, a small protein binding scaffold, and an...
Published: 6/9/2026   |   Updated: 5/29/2026   |   Inventor(s): Andrew Tsourkas, Alexander Chan
Keywords(s): Protein/Peptide (Non-Antibody), Soft Materials
Category(s): Technology Classifications > Therapeutics
Continuous Bicontinuous Interfacially Jamming Emulsion Gels (Bijel) Fabrication For Complex, Three-Dimensional Structures
Adaptation of emulsion precursor materials to enable three-dimensional printing of bijels via direct ink writing (DIW) and co-solvent vaporization. Problem: Previously developed bijel fabrication methods produce structures with limited macroscale morphologies, such as fibers, particles, and other simple 2D structures. This restriction limits the applicability...
Published: 5/15/2026   |   Updated: 5/15/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Jordan Raney, Philip Iaccarino, Damilola Lawal
Keywords(s): Bioengineering, Hydrogels, Platform Technology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Energy, Technology Classifications > Materials, Technology Classifications > Medical Devices
Antenna Reflectors Based On Stretchable Perforated Thin Films
Kirigami-based metamaterials with tunable properties for large, lightweight, and cost-effective parabolic antennas for space applications. Problem: Parabolic antennas used in space currently have a maximum diameter of about 20m. Larger antennas (e.g., with diameters of up to 100 m) would be highly beneficial, but launching such large payloads presents...
Published: 5/26/2026   |   Updated: 5/12/2026   |   Inventor(s): Igor Bargatin, Gulzhan Aldan, Sergio Pellegrino
Keywords(s): Electronic Materials, Soft Materials
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Materials
Heterostructured Film For Atmospheric Water Recovery
A nanoparticle-polymer film enables isothermal droplet formation and water recovery from humid air through capillary condensation on a porous surface. Problem: Conventional condensation of undersaturated water vapor can require energy-intensive cooling. Porous materials can condense water without cooling but often retain it inside voids. That makes...
Published: 5/6/2026   |   Updated: 4/30/2026   |   Inventor(s): Daeyeon Lee, Baek Min Kim, Amish Patel, Zachariah Vicars, Lilia Escobedo, R Bharath Venkatesh
Keywords(s): Nanotechnology, Soft Materials
Category(s): Technology Classifications > Agriculture & Environment, Technology Classifications > Materials
A Potent HIV Treatment with Low Toxicity
A small-molecule class that binds to HIV particles to improve immune response and block viral entry into cells. Problem: 37 million people worldwide currently live with HIV and an estimated 2-3 million new infections occur annually. While antiretroviral therapies do exist for those with the disease, therapy interruption leads to the re-emergence of...
Published: 11/11/2025   |   Updated: 10/30/2025   |   Inventor(s): Amos Smith, Xuchen Zhao, Tyler Higgins, Andres Finzi, Shilei Ding, Daniel Lee, Marzena Pazgier, Dung Nguyen, William Tolbert
Keywords(s): Drug Target, HIV/AIDS, Small Molecule, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics
Origami-Inspired And Remotely Adjustable Pediatric Heart Implant
Pediatric pulmonary artery band (PAB) using origami-inspired fabrication that is remotely adjustable after implantation. Problem: Congenital heart defects affect 1% of births in the United States and can lead to irregular blood flow through the main pulmonary artery (MPA). A pulmonary artery band (PAB) is an implant that can be placed on the MPA to...
Published: 11/18/2024   |   Updated: 11/18/2024   |   Inventor(s): Cynthia Sung, Gabriel Unger, Mark Fogel, Jonathan Chen, Brianna Leung
Keywords(s): Bioengineering, Cardiovascular, Pulmonary, Soft Materials, Surgery
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Robotics
Biocompatible, Reversible, and Strong Multilayered Tape for Advanced Wound Care
A hydrogel-based adhesive with a hydrophobic backing layer protects it from exposure to water and offers painless removal and easy repositioning. Problem: Reversible adhesives have gained popularity in industries with a growing emphasis on reducing waste and improving sustainability. Previously, the inventors have developed a strong and reversible adhesive...
Published: 9/12/2025   |   Updated: 7/22/2024   |   Inventor(s): Shu Yang, Baohong Chen, Alexander Tucker
Keywords(s): Bioengineering, Hydrogels, Platform Technology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials
Biodegradable Batteries Operational In The Air, Environment, And Soil
A method to fabricate batteries from biodegradable materials that can operate in the environment, such as on or under soil, and are scalable in size. Problem: Recently there have been significant developments in biodegradable sensors, which can perform environmental measurements (e.g., on or below the surface of soil) for a specific time and then...
Published: 9/12/2025   |   Updated: 5/20/2024   |   Inventor(s): Jingwen Zhang, Mark Allen
Keywords(s): Electronic Materials, Hydrogels, Internet of Things, Nanotechnology, Soft Materials
Category(s): Technology Classifications > Research Tools & Reagents, Technology Classifications > Agriculture & Environment, Technology Classifications > Energy, Technology Classifications > Materials
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