Search Results - yuling+chen

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Inhalable Dry Powder Biosensor Platform for Noninvasive Detection and Monitoring of Pulmonary Disease Activity

This technology uses inhalable dry powder biosensors that detect lung disease by releasing a reporter molecule in response to disease-related enzymes; the reporter is then measured in urine, enabling fast, noninvasive diagnosis and monitoring of lung conditions. Background Chronic respiratory diseases (CRDs) and lung cancer represent significant global...

Published: 7/29/2026 | Updated: 7/29/2026 | Inventor(s): Qian Zhong, Robert Williams, Yuling Chen, Karlie Flader, Chaeho Moon, Darya Razmara

Keywords(s):

Category(s): Life sciences > Diagnostic, Life sciences > Therapeutics > Formulation

Privacy-Preserving Intelligent Search for Distributed Video Surveillance

This technology lets users search surveillance video in real time using simple descriptions, solving the problem that current systems rely on sending large amounts of video or using biometric tools that are slow and raise privacy concerns. By processing data closer to where it is collected, the system delivers faster results, protects privacy, and uses...

Published: 7/24/2026 | Updated: 4/10/2026 | Inventor(s): Yu Chen, Seyed yahya Nikouei

Keywords(s):

Category(s): Campus > Binghamton University, Technology Classifications, Technology Classifications > Engineering

Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Updated: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 2/26/2026 | Updated: 11/18/2025 | Inventor(s): Feng Yan, Lin Li

Keywords(s):

Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Task-Oriented Edge Metaverse for Smart Cities and Critical Systems

This invention introduces a task-oriented “Microverse” architecture that creates temporary, edge-based digital twins for 5G/IoT network slices. By combining real-time data fusion, per-task blockchain security, and immersive VR/AR interfaces, it delivers sub-second situational awareness and secure collaboration for smart cities, infrastructure,...

Published: 7/24/2026 | Updated: 10/17/2025 | Inventor(s): Yu Chen, Qian Qu

Keywords(s): Technologies

Category(s): Campus > Binghamton University

High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases

Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...

Published: 6/22/2026 | Updated: 5/27/2025 | Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An

Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment

Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals

Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation

Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...

Published: 6/22/2026 | Updated: 10/2/2023 | Inventor(s): Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang

Keywords(s): Drug Discovery, Infectious Diseases Treatment

Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology

Real-Time RT-PCR Assay for the Rapid Detection of Rabies and Other Lyssaviruses

Rabies occurs in more than 150 countries and territories, resulting in at least 55,000 human deaths per year worldwide according to World Health Organization estimates. Rabies is a vaccine-preventable viral disease caused by numerous lyssaviruses that are found in a variety of animal species throughout the world. Rabies virus infects the central nervous...

Published: 4/24/2025 | Updated: 12/6/2022 | Inventor(s): Yu Li

Keywords(s): assay, DA4XXX, DDXXXX, Diagnostics, LYSSAVIRUSES, Modified, NCEZID, NCEZID-DHCPP, Non-rabies, Probe, rabies, REAL-TIME, RT-PCR, VLXXXX, VOXXXX, WBXXXX, WGXXXX, WHXXXX, WIXXXX, XEXXXX, YBXXXX, YGXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Therapeutics, Application > Research Materials, Application > Diagnostics

Universal Diagnostic Assay for Detection and Identification of Poxviruses in Clinical Samples

CDC researchers have developed an assay for detection and diagnosis of poxviruses within clinical samples or from lab culture-systems. The assay specifically targets chordopoxviruses (except avipoxviruses) for PCR-based identification; an improvement upon the current standard of cell culturing methodologies. Individual chordopoxvirus species can cause...

Published: 4/24/2025 | Updated: 12/6/2022 | Inventor(s): Inger Damon, Hui Zhao, Yu Li

Keywords(s): ASSAYS, CDC Docket Import, CDC Docket Import CDC Prosecuting, CHORDOPOXVIRUSES, DA4BXX, DA4XXX, DAXXXX, diagnostic, DXXXXX, OID-NCEZID-DHCPP, VLXXXX, VOXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Diagnostics, Application > Research Materials

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Updated: 9/1/2022 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

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