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Search Results - james+leahy
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Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation
Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...
Published: 10/2/2023
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Inventor(s):
Yu Chen
,
Michael Sacco
,
James Leahy
,
Elena Bray
,
Xingmin Sun
,
Xiujun Zhang
Keywords(s):
Drug Discovery
,
Infectious Diseases Treatment
Category(s):
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Biotechnology
Methods for the Treatment of Inflammation
Advantages: Exceptional precision in addressing inflammation, minimizing potential side effects. Unique COX-2 interaction reduces the risk of adverse reactions. Versatile effectiveness across various inflammatory disorders, providing relief to a wide range of patients. Summary: This technology addresses a significant healthcare challenge...
Published: 11/7/2024
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Inventor(s):
Bill Baker
,
Sofia Kokkaliari
,
James Leahy
,
Wayne Williams
Keywords(s):
Inflammation
,
Pain Relief / Management
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Oncology
Novel Bronchodilators For Treating Obstructive Lung Disease
Competitive Advantages Identified novel bronchodilators agonists that relax airway smooth muscle Could be a novel therapeutic for asthma and other obstructive lung diseases Could also be a therapeutic for other types of bronchoconstriction caused by smoke or anaphylaxis Summary Currently patients with obstructive airways diseases have...
Published: 2/19/2025
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Inventor(s):
Stephen Liggett
,
James Leahy
,
Donghwa Kim
,
Steven An
Keywords(s):
Medical Therapeutics Cell Therapy
,
Respiratory Diseases
,
Respiratory Diseases Treatment
,
Therapeutics
Category(s):
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
Synthesis of Cannabinoids and Novel Analogs
Competitive Advantages Inexpensive and scalable synthesis process Commercially available reagent used as starting product Provides a synthesis method for generation of novel analogs Quantification of minor cannabinoids Summary “Medical marijuana” is a hot topic but more biomedical research is needed demonstrating the health benefits...
Published: 1/31/2025
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Inventor(s):
James Leahy
,
Zachary Shultz
,
Grant Lawrence
Keywords(s):
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical