Search Results - james+leahy

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Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation
­Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...
Published: 10/2/2023   |   Inventor(s): Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang
Keywords(s): Drug Discovery, Infectious Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology
Methods for the Treatment of Inflammation
­Advantages: Exceptional precision in addressing inflammation, minimizing potential side effects. Unique COX-2 interaction reduces the risk of adverse reactions. Versatile effectiveness across various inflammatory disorders, providing relief to a wide range of patients. Summary: This technology addresses a significant healthcare challenge...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Sofia Kokkaliari, James Leahy, Wayne Williams
Keywords(s): Inflammation, Pain Relief / Management
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Oncology
Novel Bronchodilators For Treating Obstructive Lung Disease
­Competitive Advantages Identified novel bronchodilators agonists that relax airway smooth muscle Could be a novel therapeutic for asthma and other obstructive lung diseases Could also be a therapeutic for other types of bronchoconstriction caused by smoke or anaphylaxis Summary Currently patients with obstructive airways diseases have...
Published: 5/21/2024   |   Inventor(s): Stephen Liggett, James Leahy, Donghwa Kim, Steven An
Keywords(s): Medical Therapeutics Cell Therapy, Respiratory Diseases, Respiratory Diseases Treatment, Therapeutics
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics
Synthesis of Cannabinoids and Novel Analogs
Competitive Advantages Inexpensive and scalable synthesis process Commercially available reagent used as starting product Provides a synthesis method for generation of novel analogs Quantification of minor cannabinoids Summary “Medical marijuana” is a hot topic but more biomedical research is needed demonstrating the health benefits...
Published: 9/3/2024   |   Inventor(s): James Leahy, Zachary Shultz, Grant Lawrence
Keywords(s):  
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical
Anti-infective Agents with Novel Chemical Scaffolds
Competitive Advantages Potentially more effective than current treatments Less toxic than current treatments Treats a variety of bacterial pathogens Compound can be administered in a variety of delivery methods Summary Heat Shock Protein 90 (Hsp90) is known to be a highly conserved protein amongst these bacterial pathogens and...
Published: 8/26/2023   |   Inventor(s): Ankush Kanwar, Benjamin Eduful, Brian Vesely, Dennis Kyle, Linda Barbeto, James Leahy
Keywords(s):  
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical