Search Results - stephen+liggett

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Coherent Generation Of High-Dimensional Structured Light Using A Hyperdimensional Spin-Orbit Microlaser

The current invention describes next-generation high-capacity noise-resilient communication and computing technology. The invention describes a method to coherently generate high-dimensional structured light, including spin-orbit states, in an integrated and scalable way. Problem: On-chip information technologies are mostly limited to two-level systems...

Published: 10/16/2023 | Inventor(s): Liang Feng, Zhifeng Zhang, Haoqi Zhao, Li Ge

Keywords(s): Augmented Reality (AR) & Virtual Reality (VR), Optics & Photonics

Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Materials, Technology Classifications > Imaging

Alternative Gαs-promoting agonist Bronchodilator

Competitive Advantages Novel compounds and methods for selecting targeting β2AR receptors to treat obstructive lung diseases The method might improve airway response with reduced tachyphylaxis Biasing towards β-arrestin and away from G protein coupling can be attained, which can be therapeutically favorable for certain receptors...

Published: 5/23/2024 | Inventor(s): Stephen Liggett, Donghwa Kim, Marcello Giulianotti

Keywords(s): Biotechnology, Respiratory Diseases, Respiratory Diseases Treatment

Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Biotechnology

Novel Bronchodilators For Treating Obstructive Lung Disease

Competitive Advantages Identified novel bronchodilators agonists that relax airway smooth muscle Could be a novel therapeutic for asthma and other obstructive lung diseases Could also be a therapeutic for other types of bronchoconstriction caused by smoke or anaphylaxis Summary Currently patients with obstructive airways diseases have...

Published: 5/21/2024 | Inventor(s): Stephen Liggett, James Leahy, Donghwa Kim, Steven An

Keywords(s): Medical Therapeutics Cell Therapy, Respiratory Diseases, Respiratory Diseases Treatment, Therapeutics

Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics

Inhibition of Beta-Arrestin 1 and Beta-Arrestin2 Oligomerlzation in Taupathy

Competitive Advantages Small molecule inhibitors that target beta-arrestin oligomerization and accumulation of pathogenic tau Novel treatment for tauopathies Could be a therapeutic for numerous neurodegenerative disorders Summary Tau pathology (tauopathy) is a prevailing hallmark of multiple neurodegenerative disease, including Alzheimer’s...

Published: 5/23/2024 | Inventor(s): Jung A Woo, Stephen Liggett, David Kang

Keywords(s): Neurodegenerative Diseases, Therapeutics

Category(s): Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical

A Method to Reduce the Downregulation of Beta2-adrenergic Receptors in Asthma and COPD

Advantages Discovered a new mechanism responsible for ∼50% of the β agonist-promoted down-regulation of β2Ars. Let-7f miRNA reduces β2-adrenergic receptor (β2AR) downregulation in airway smooth muscle cells. Targets microRNA let-7f to mitigate β-agonist-induced tachyphylaxis and improve efficacy in asthma and COPD treatments. Offers...

Published: 8/22/2024 | Inventor(s): Stephen Liggett, Donghwa Kim

Keywords(s):

Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

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Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers

Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources

All-Fiber Multicore Fiber Laser Devices

Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources