Search Results - infectious+diseases+treatment

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New natural product scaffolds with activity against respiratory syncytial virus from the Antarctic Sponge Suberites sp.
­Advantages: This research introduces a novel class of compounds, including neosuberitenone, which demonstrates selectivity against respiratory syncytial virus (RSV). The research's focus on small molecules derived from a natural source, the Antarctic sponge Suberites sp., hints at the potential for cost-effective treatments. The identified...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Joe Bracegirdle, Stine Olsen, Michael Teng, Kim Tran, Charles Amsler, James McClintock
Keywords(s): Antiviral Therapeutics, Infectious Diseases Treatment, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Infectious Diseases
Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation
­Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...
Published: 10/2/2023   |   Inventor(s): Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang
Keywords(s): Drug Discovery, Infectious Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology
RAiD2: Robotics and AI for Onsite Detection and Disinfection
Advantages: Precise and non-contact disinfection User-friendly and portable autonomous operation Robotic and AI-augmented advanced control Business Summary: The RAiD2 platform combats biological threats, particularly during the COVID-19 pandemic. The platform integrates multiplexed nucleic acid-based biosensing for onsite detection, corona...
Published: 9/4/2024   |   Inventor(s): Ying Zhong, Subhra Mohapatra, Shyam Mohapatra, Ehsan Sheybani, Tansel Yucelen
Keywords(s): Artificial Intelligence, Electronics, Infectious Diseases Treatment, Medical Devices, Robotics, Sensors
Category(s): Technology Classifications > Data/AI > D/AI Imaging, Technology Classifications > Electronics > Electronics Sensors, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Engineering > Sensors, Technology Classifications > Medical > Biomaterials, Technology Classifications > Medical, Technology Classifications > Medical > Medical Sensors
Antimalarial peptides
­Competitive Advantages Potential treatment for malaria Could be effective against drug resistant strain Dd2 The resulting compounds showed no significant cytotoxicity Summary Malaria, caused by the parasite Plasmodium falciparum, continues to threaten much of the world population and there is a pressing need for expanding treatment options....
Published: 11/7/2024   |   Inventor(s): Bill Baker, Joe Bracegirdle, James Rocca, John Adams, Nerida Wilson, Debora Casandra, Xingmin Sun, Anne-Claire Limon
Keywords(s): Infectious Diseases Treatment, Peptides, Therapeutics
Category(s): Technology Classifications > Chemistry, Technology Classifications > Medical > Infectious Diseases
Cistron Mediated Intrinsic Interferon and Antiviral Response in Human Placenta
Competitive Advantages Predict susceptibility for infection or severity of infection in pregnant women Reduced viral infections during pregnancy Protection of both maternal and fetal health against infections Uses the placenta at the maternal-fetal interfaces for antiviral response Summary Viral infections during pregnancy have often caused...
Published: 8/21/2024   |   Inventor(s): Hana Totary-Jain
Keywords(s): Infectious Diseases Treatment, Women’s Health
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Womens Health
Tetrazole & Coumarin Phosphonate Based Broad-Spectrum Beta-Lactamase Inhibitors
Competitive Advantages Combats bacterial antibiotic resistance to β-Lactamase Effectively inhibits against the different classes of β-Lactamase Enhances effectiveness of current β-lactam antibiotics treatments Summary Our inventors have discovered tetrazole and coumarin phosphonate based compounds can actively inhibit...
Published: 6/27/2024   |   Inventor(s): Yu Chen, Orville Pemberton, Adam Renslo, Priyadarshini Jaishankar
Keywords(s): Infectious Diseases Treatment, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical
Beta-Lactamase Inhibitor Compositions, Methods of Use, and Methods of Treatment
Competitive Advantages Can restore the efficacy of beta-lactam antibiotics Overcomes antibiotic resistance May help to develop new antibiotic treatment regimens Treats multi-drug resistant organisms Summary Our researchers have developed compositions comprised of a beta-lactamase inhibitor and methods of use to treat various infections and...
Published: 6/27/2024   |   Inventor(s): Adam Renslo, Derek Nichols, Priyadarshini Jaishankar, Yu Chen, Erica Lauterwasser
Keywords(s): Infectious Diseases Treatment, Pharmaceuticals
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical
Mangrove Endophytic Fungal Natural Products Inhibit Mycobacterium Tuberculosis
Competitive Advantages Novel secondary metabolite from mangrove endophytic fungi Inhibits Myobacterium tuberculosis Low cytotoxicity in humans Summary Our inventors have isolated secondary metabolites from mangrove endophytic fungi that target M. tuberculosis and inhibits its growth. Many of these metabolites have between 70% to...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Kyle Rohde, Bingjie Yang, Marisa Fuse
Keywords(s): Health Tech, Infectious Diseases Treatment, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical