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Search Results - steven+an
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Combating Potential Misinformation in Journalism: A Hybrid Framework using LLMs and Heuristic Approaches
Background The rapid dissemination of news is an important factor for the global population to stay up to date with current events, or to make well-informed decisions in dynamic sectors like the stock market. Journalists typically include large amounts of quantitative information using data visualization to help enhance accessibility and comprehension...
Published: 6/17/2025
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Inventor(s):
Arlen Fan
,
Fan Lei
,
Steven Corman
,
Ross Maciejewski
Keywords(s):
Category(s):
Artificial Intelligence/Machine Learning
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Physical Science
,
Cybersecurity
UCLA CRISPR Licensing Program
UCLA CRISPR Licensing Program A major challenge in CRISPR-based gene editing is efficient delivery of the editing system to target cells. UCLA has filed patents on plant viral delivery vectors expressing highly-miniaturized CRISPR systems that may overcome these challenges. The technology is based on recent work from the Jacobsen (UCLA) and Doudna...
Published: 7/17/2025
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Inventor(s):
Steven Jacobsen
,
Jennifer Doudna
Keywords(s):
Category(s):
Therapeutics > Gene Therapy And Editing
Companion Diagnostic for Immunomodulatory Repair Treatments
This technology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
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Inventor(s):
Steven Goldman
,
Daniel Benson
,
Adrian Grijalva
,
Jordan Fink
,
Jordan Lancaster
,
Jennifer Koevary
,
Simar Singh
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Diagnostics
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Technology Classifications > Research Tools > Screening assays
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Technology Classifications > Healthcare Portfolios > Heart and Vascular
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
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Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
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Technology Classifications > Medical > Therapeutics
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Technology Classifications > Medical > Pharmaceuticals
Blocking Covid-19 Virus from Entering the Nares, Nasolaryngeal and Pulmonary Airways Using Ace2 Peptides
Prevents initial COVID-19 infection and neutralizes COVID-19 in an existing pulmonary infection. Background: COVID-19 remains one of the primary global health issues facing society today. The economic and social impact of the virus will likely be significant for the foreseeable future. Although effective vaccines have been developed, COVID-19 infection...
Published: 5/13/2025
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Inventor(s):
Matthew Pincus
,
Steven Evans
,
Fred Friedman
Keywords(s):
Technologies
Category(s):
Campus > SUNY Downstate Health Sciences University
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Technology Classifications > Biomedical Science and Engineering
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Technology Classifications > Healthcare
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Technology Classifications > Therapeutics and Vaccines
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Technology Classifications > Viral Vectors
Use and Administration of Ess1 Inhibitors to Treat Fungal Infections
A new class of antifungal drugs to treat resistant fungal infections. Background: Fungal Infections are a major cause of human disease. Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year.The four classes of antifungal drugs to treat life-threatening infections have...
Published: 5/13/2025
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Inventor(s):
Steven Hanes
,
Stephen Parent
,
Charles Boone
,
Sheena Li
Keywords(s):
Category(s):
Technology Classifications > Therapeutics and Vaccines
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Technology Classifications > Biomedical Science and Engineering
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Campus > Upstate Medical University
Precision Distance Estimation Using GPS
Accurately estimates distance traveled and speed using GPS location technology. Background: GPS locations (called "way points") are typically collected and stored to keep track of the path of motion. When this data is used to estimate distance traveled, the error in the individual locations results in a bias, so that the actual distance...
Published: 7/2/2025
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Inventor(s):
Steven Crain
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Information Technology
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Campus > SUNY Plattsburgh
Whole Blood Transcript Clusters for Ischemic Stroke Detection
Provides a better method for diagnosing acute ischemic stroke. Background: Strokes result from reductions of blood flow to the brain and are second to coronary heart disease in terms of vascular disease incidence, morbidity, and mortality. About 83% of strokes are due to arterial vascular occlusion (ischemic stroke), and about 17% are due to vascular...
Published: 5/13/2025
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Inventor(s):
Alison Baird
,
Mateusz Adamski
,
Steven Soper
,
Malgorzata Witek
Keywords(s):
Category(s):
Campus > SUNY Downstate Health Sciences University
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Technology Classifications
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Technology Classifications > Research Tools and Reagents
Competency Med Assessment Pro
Invention Summary: Competency Medical Assessment Pro (MAP) is a real‐time online assessment system developed as an innovative solution designed to streamline the feedback process to medical students, focusing on the 13 Entrustable Professional Activities (EPAs) essential for medical school graduation, as outlined by the AAMC (American Association...
Published: 5/9/2025
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Inventor(s):
Archana Pradhan
,
Steven Wen
,
Guangde He
,
Jie Zhao
Keywords(s):
Category(s):
Technology Classifications > Software & Copyright
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Technology Classifications > Software & Algorithms
Buccal swab-based biomarkers for schizophrenia
mRNA normalized fold expression from transcript of interest Invention Summary: Schizophrenia (SCZ) is a debilitating and chronic brain disorder characterized by symptoms, such as hallucinations, delusions, and disorganized thoughts. Current diagnostic criteria rely solely on behavioral observations and do not account for molecular and clinical...
Published: 4/30/2025
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Inventor(s):
Bonnie Firestein-Miller
,
Irving Vega
,
Steven Silverstein
Keywords(s):
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Diagnostics
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