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Search Results - steven+an
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High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
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Technology Classifications > Medical > Therapeutics
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Technology Classifications > Medical > Pharmaceuticals
Blocking Covid-19 Virus from Entering the Nares, Nasolaryngeal and Pulmonary Airways Using Ace2 Peptides
Prevents initial COVID-19 infection and neutralizes COVID-19 in an existing pulmonary infection. Background: COVID-19 remains one of the primary global health issues facing society today. The economic and social impact of the virus will likely be significant for the foreseeable future. Although effective vaccines have been developed, COVID-19 infection...
Published: 5/13/2025
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Inventor(s):
Matthew Pincus
,
Steven Evans
,
Fred Friedman
Keywords(s):
Technologies
Category(s):
Campus > SUNY Downstate Health Sciences University
,
Technology Classifications > Biomedical Science and Engineering
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Technology Classifications > Healthcare
,
Technology Classifications > Therapeutics and Vaccines
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Technology Classifications > Viral Vectors
Use and Administration of Ess1 Inhibitors to Treat Fungal Infections
A new class of antifungal drugs to treat resistant fungal infections. Background: Fungal Infections are a major cause of human disease. Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year.The four classes of antifungal drugs to treat life-threatening infections have...
Published: 5/13/2025
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Inventor(s):
Steven Hanes
,
Stephen Parent
,
Charles Boone
,
Sheena Li
Keywords(s):
Category(s):
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Biomedical Science and Engineering
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Campus > Upstate Medical University
Precision Distance Estimation Using GPS
Accurately estimates distance traveled and speed using GPS location technology. Background: GPS locations (called "way points") are typically collected and stored to keep track of the path of motion. When this data is used to estimate distance traveled, the error in the individual locations results in a bias, so that the actual distance...
Published: 5/13/2025
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Inventor(s):
Steven Crain
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Information Technology
,
Campus > SUNY Plattsburgh
Whole Blood Transcript Clusters for Ischemic Stroke Detection
Provides a better method for diagnosing acute ischemic stroke. Background: Strokes result from reductions of blood flow to the brain and are second to coronary heart disease in terms of vascular disease incidence, morbidity, and mortality. About 83% of strokes are due to arterial vascular occlusion (ischemic stroke), and about 17% are due to vascular...
Published: 5/13/2025
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Inventor(s):
Alison Baird
,
Mateusz Adamski
,
Steven Soper
,
Malgorzata Witek
Keywords(s):
Category(s):
Campus > SUNY Downstate Health Sciences University
,
Technology Classifications
,
Technology Classifications > Research Tools and Reagents
Competency Med Assessment Pro
Invention Summary: Competency Medical Assessment Pro (MAP) is a real‐time online assessment system developed as an innovative solution designed to streamline the feedback process to medical students, focusing on the 13 Entrustable Professional Activities (EPAs) essential for medical school graduation, as outlined by the AAMC (American Association...
Published: 5/9/2025
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Inventor(s):
Archana Pradhan
,
Steven Wen
,
Guangde He
,
Jie Zhao
Keywords(s):
Category(s):
Technology Classifications > Software & Copyright
,
Technology Classifications > Software & Algorithms
Buccal swab-based biomarkers for schizophrenia
mRNA normalized fold expression from transcript of interest Invention Summary: Schizophrenia (SCZ) is a debilitating and chronic brain disorder characterized by symptoms, such as hallucinations, delusions, and disorganized thoughts. Current diagnostic criteria rely solely on behavioral observations and do not account for molecular and clinical...
Published: 4/30/2025
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Inventor(s):
Bonnie Firestein-Miller
,
Irving Vega
,
Steven Silverstein
Keywords(s):
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Diagnostics
Solvent System for Temperature Efficient Extraction of Pure Water from Saline Brine
The Problem: Desalination of high-salinity brine solutions, a byproduct of various industrial processes and seawater desalination, poses challenges due to inefficiencies and high energy consumption of conventional methods. Reverse osmosis struggles with fouling and scaling due to the high concentration of dissolved solids. Distillation is energy-intensive...
Published: 4/24/2025
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Inventor(s):
Steven Weinman
,
Jason Bara
,
Heath Turner
,
Gabriel Barbosa
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Manufacturing
,
Technology Classifications > Healthcare
Spring-loaded paddle for surfboard/watercraft propulsion
Image legend: Design of surfboard with extra propulsion Invention Summary: Surfing’s growth has been rapidly on the rise since the surf media influence of the 1960s and the commercialization of the industry in the 70s and 80s. But recent years have shown us that surfing is truly starting to go mainstream. However, the learning curve...
Published: 4/14/2025
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Inventor(s):
Alyssa Nayar
,
Jin-Hyuk Choi
,
Douglas Willey
,
Dominick Luppino
,
Steven Coponi
,
Aaron Mazzeo
Keywords(s):
Category(s):
Technology Classifications > Physical Sciences & Engineering
Door Alarm System that Monitors an Open Door for Intrusions
Background There has been a recent rise in the number of people impersonating delivery workers, and is partially due to home alarms only being sold to secure closed doors. By analyzing the interaction between homeowners and burglars, it was apparent burglars can exploit this flaw by assuming a fake identity to persuade homeowners to disable their alarm...
Published: 3/4/2025
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Inventor(s):
Michael Valentine
,
Chao Wang
,
Steven Desch
,
Mohammad Almutairi
,
Antonio Veguilla Hernandez
,
Logan Mahoney
Keywords(s):
Category(s):
Physical Science
,
Wireless & Networking
,
Applied Technologies
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