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AtriaLink: Custom Implantable Pacing Platform with BLE Control to Induce Persistent Atrial Fibrillation in Large Animal Models

This technology, AtriaLink, is a custom implantable cardiac pacing platform developed in collaboration between the Goldman and Gutruf Laboratories at the University of Arizona. It is designed to provide a fully configurable and implantable system for induction of persistent atrial fibrillation (AFib) in swine through chronic atrial pacing. The device...

Published: 5/18/2026 | Updated: 5/18/2026 | Inventor(s): Steven Goldman, Talal Moukabary, Philipp Gutruf, Daniel Benson, Fox Bravo, Rey Mendoza, Jesse Riemenschneider, Lucas Mellinger, Kian Sadat, Adrian Grijalva

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations, Technology Classifications > Medical Devices, Technology Classifications > Research Tools > Animal Models

Drug-Regulatable, Inducible Expression of Membrane-Bound Interleukin 12 (DRIM-IL-12) for Use in Adoptive Cell Therapy

Summary: Scientists at the National Cancer Institute (NCI) have developed a novel tightly regulated drug-responsive, membrane-bound IL-12 cytokine platform, that enhances anti-tumor efficacy in adoptive cell therapy (ACT) with engineered T-cells (CAR, TCR, TILs) while improving safety. The NCI seeks research co-development partners and/or licensees...

Published: 5/14/2026 | Updated: 5/14/2026 | Inventor(s): Steven Rosenberg, Sanghyun (Peter) Kim

Keywords(s):

Category(s): Application > Therapeutics, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration

Rondelle intelligente de hockey sonore

AUDIBLE HOCKEY PUCK A smart audible device for visually impaired and blind hockey players iStock - 183286613 UNMET NEED To improve their inclusion, multiple organisms have the mission to encourage visually impaired and blind people to participate in sport activities at all levels, from grassroots to the Paralympic Games. Some sports have...

Published: 6/8/2026 | Updated: 5/12/2026 | Inventor(s): Steve Vezeau, Frédéric Nabki, Félix-Antoine Leclerc, Mounir Boukadoum, Jessika Champagne, Jasmin Bolduc, Raphaël Guimond

Keywords(s): Innovation

Category(s): Applications > Informatique, micro-électronique et télécommunications > Matériel et composants électroniques > Composants micro-électroniques (semi-conducteurs, MEMS, circuits, résonateurs, cellules solaires), English Applications > IT, microelectronics and telecommunications > Electronic equipment and components > Microelectronic components (semiconductors, MEMS, circuits, resonators, solar cells), Objectifs de Développement Durable > ODD 10 : Inégalités réduites, Objectifs de Développement Durable > ODD 09 : Industrie, innovation et infrastructure, Secteurs, Secteurs > Sciences et génie, Sectors > Science and Technologies, Sustainable Development Goals > Goal 09: Industry, Innovation, and Infrastructure, Sustainable Development Goals > Goal 10: Reduced Inequalities

DNA EndosomaL Escape Vehicle Response (DELVR) as a Platform to Boost Antisense Oligonucleotide (ASO) Efficacy

Application A versatile delivery platform for antisense oligonucleotides (ASOs) enabling transient downregulation of protein expression. Key Benefits Broadly boost the efficacy of nucleic acid-based drugs. Drastic reduction in toxicity. DELVR strategy can rescue clinically tested ASOs that didn’t progress to FDA approval due to off-target...

Published: 5/22/2026 | Updated: 4/22/2026 | Inventor(s): Steven Narum, Khalid Salaita

Keywords(s): Gene Therapy and Editing, Nanoparticle Drug Delivery, Platform, Rare and Orphan Disease Treatments, Therapeutics

Category(s): TechPub Algolia > Micro and Nanotechnology

Method for formation, compaction, sealing and disposal of CO2 hydrates on the seabed

Background: The rising levels of atmospheric carbon dioxide (CO2) present a critical global challenge, significantly contributing to climate change and ocean acidification. Current CO2 sequestration methods, such as geological storage, face numerous hurdles, including leakage risks, high costs, and the need for extensive monitoring. An emerging method...

Published: 5/12/2026 | Updated: 4/9/2026 | Inventor(s): Vaibhav Bahadur, Awan Bhati, ManojKumar Lokanathan, Steve Smaha

Keywords(s):

Category(s): Physical sciences > Energy > Renewable, green, or transitional energy, Physical sciences > Environmental & sustainable solutions

Genetically engineered cell surface biosensors for high-throughput detection, screening, and recovery of rare earth elements

This technology uses genetically engineered yeast cells displaying fluorescent sensors to detect and recover rare earth elements from solutions, enabling rapid, specific, and scalable metal screening and extraction using fluorescence signals and high-throughput sorting. Background Rare earth elements (REEs) are a group of 17 chemically similar metals...

Published: 3/30/2026 | Updated: 3/30/2026 | Inventor(s): Manish Kumar, Marcus Benyamin, Steven Zilko, Andrew Ellington, Benjamin Keitz, Randall Hughes

Keywords(s):

Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Therapeutics > Synthetic biology

Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels

This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...

Published: 5/1/2026 | Updated: 3/23/2026 | Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays

Engineered Models of Human Embryo Implantation - Microfabricated Cell Culture Platforms to Increase the Efficiency and Timing of Blastoid Formation and their Lineage Representation (UCLA Case No. 2026-074)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 6/3/2026 | Updated: 3/4/2026 | Inventor(s): Steven Jonas, Kathrin Plath

Keywords(s):

Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Women's Health

Gene-Modified Conventional Type 1 Dendritic Cells (UCLA Case No. 2026-093)

UCLA researchers in the Departments of Medicine and Pulmonary Disease have recently developed a novel approach for improving the long-term efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer. BACKGROUND: Non-small cell lung cancer (NSCLC) is one of the most common types of lung cancer. Anti-PD-1 immunotherapy is used for treatment despite...

Published: 5/16/2026 | Updated: 3/4/2026 | Inventor(s): Bin Liu, Steven Dubinett

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Gene Therapy And Editing, Therapeutics > Vaccines

Dark Eye Harvester

This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...

Published: 2/9/2026 | Updated: 2/9/2026 | Inventor(s): A Departmental Work, Michael Brown

Keywords(s):

Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools

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