Search Results - steven+an

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Engineered Models of Human Embryo Implantation - Microfabricated Cell Culture Platforms to Increase the Efficiency and Timing of Blastoid Formation and their Lineage Representation (UCLA Case No. 2026-096)
Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.
Published: 3/4/2026   |   Inventor(s): Steven Jonas
Keywords(s):  
Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Women's Health
Gene-Modified Conventional Type 1 Dendritic Cells (UCLA Case No. 2026-093)
Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.
Published: 3/4/2026   |   Inventor(s): Steven Dubinett
Keywords(s):  
Category(s): Therapeutics > Immunology And Immunotherapy
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Nanoparticle & dsDNA Toolkit for Decreased Toxicity and Gene Editing of Epithelial Stem Cells via Epithelial Disruption (UCLA Case No. 2023-205/209) -- for Cystic Fibrosis and other genetic diseases
UCLA researchers in the Department of Pediatrics, Hematology/ Oncology have constructed a nanoparticle toolkit for increased integration and reduced toxicity for gene therapies that treat debilitating diseases such as Cystic Fibrosis and other critical genetic diseases. BACKGROUND: Gene therapies are the forefront of therapeutic advancements as a one-off...
Published: 12/1/2025   |   Inventor(s): Steven Jonas, Brigitte Gomperts, Donald Kohn
Keywords(s):  
Category(s): Therapeutics > Gene Therapy And Editing, Platforms > Drug Delivery
Curative Locoregional Therapy Using Ablation or Catheter-Based Embolization of Targeted Hepatocellular Carcinoma by Delivering Supercharged NK Cells and CAR-NK or CAR-T Cells (UCLA Case No. 2023-115)
UCLA researchers in the School of Dentistry and Interventional Radiology have developed a groundbreaking curative treatment for hepatocellular carcinoma that combines locoregional therapy, such as ablation or catheter-based embolization, with targeted delivery of supercharged NK cells and CAR-NK or CAR-T cells, offering a highly effective approach that...
Published: 10/31/2025   |   Inventor(s): Anahid Jewett, Steven Raman, Jason Chiang
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy
Lipid Nanoparticle-Mediated Delivery of Gene Editing Reagents for Targeted Disruption of Oncogenic Drivers in C-Myc Overexpressing Malignancies (UCLA Case No. 2025-9A9)
Contact UCLA Technology Development Group to learn more.
Published: 9/19/2025   |   Inventor(s): Steven Jonas, Tanya Stoyanova
Keywords(s):  
Category(s): Therapeutics > Gene Therapy And Editing, Therapeutics > Oncology
Co-Deacidification and Dechlorination of Aqueous/Gaseous Streams by Mineral Dissolution (Case No. 2022-173)
Summary UCLA researchers have developed a method and composition for simultaneous deacidification and dechlorination of acidic aqueous solutions (including brines or electrolyte streams enriched in free-chlorine species), using mineral or rock solids containing low-valent metals to neutralize acidity and remove chlorine contaminants. Background Electrolytic...
Published: 9/11/2025   |   Inventor(s): Gaurav Sant, David Jassby, Xin Chen, Dante Simonetti, Steven Bustillos
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Materials > Membranes, Materials > Nanotechnology, Energy & Environment
Selective Expansion of Engineered TCR-T Cells for Use in Adoptive Cell Immunotherapy
Summary: The National Cancer Institute (NCI) seeks capable licensees interested in commercializing T cell receptor (TCR)-engineered T cells expressing murine/human hybrid receptors. Description of Technology: TCR-T therapies, particularly those targeting patient-specific neoantigens, remain a promising approach to the treatment metastatic cancers....
Published: 8/25/2025   |   Inventor(s): Steven Feldman, Steven Rosenberg, Drew Deniger
Keywords(s):  
Category(s): Application > Therapeutics, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Collaboration Sought > Licensing
Selective Expansion of Engineered TCR-T Cells for Use in Adoptive Cell Immunotherapy
Summary: The National Cancer Institute (NCI) seeks capable licensees interested in commercializing T cell receptor (TCR)-engineered T cells expressing murine/human hybrid receptors. Description of Technology: TCR-T therapies, particularly those targeting patient-specific neoantigens, remain a promising approach to the treatment metastatic cancers....
Published: 8/25/2025   |   Inventor(s): Steven Feldman, Steven Rosenberg, Drew Deniger
Keywords(s):  
Category(s): Application > Therapeutics, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Collaboration Sought > Licensing
C8166-45 Cells
Summary: The National Cancer Institute (NCI) seeks licensees for a human T-cell line, C8166-45, transformed by HTLV-1. C8166-45, also known as C63/CRII-2, contains three transcriptionally active proviruses useful for testing biological activities involved in T-cell immortalization and growth. Description of Technology: ...
Published: 8/21/2025   |   Inventor(s): Genoveffa Franchini, Syed Salahuddin, Flossie Wong-Staal, Robert Gallo, Phillip Markham, V Kalyanaraman
Keywords(s):  
Category(s): Application > Research Materials, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, Collaboration Sought > Licensing
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