Search Results - george+sutphin

3 Results

Sort By:

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Novel Antibiotic Drug Combination Including an Anti-Inflammatory Metabolite

This technology involves a combination of a metabolite, 3-hydroxyanthanilic acid (3HAA) with a compound that alters cellular iron homeostasis (e.g. an iron chelator or an iron supplement) that produces synergistic antibiotic interaction. 3HAA sensitizes bacteria to changes in iron availability (both increasing iron media content through supplementation...

Published: 3/12/2024 | Inventor(s): George Sutphin, Luis Espejo

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics

Anti-Aging via HAAO Blockers

This invention relates to methods of preventing or treating age-related diseases comprising targeting the kynurenine pathway by blocking, reducing expression, or reducing activity of 3-hydroxyanthranilic acid dioxygenase (HAAO), and or increasing the bioavailability of 3-hydroxyanthranilic acid (3HAA). Background: Human diseases are characterized...

Published: 3/12/2024 | Inventor(s): George Sutphin

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences