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Monitoring Structural Health Using Diffractive Optical Processors (Case No. 2025-201)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel structural health monitoring system that is highly accurate and cost effective, addressing limitations in current infrastructure and civil health monitoring and a rise in public safety concerns. Background: The need for structural health monitoring...
Published: 12/5/2025   |   Inventor(s): Aydogan Ozcan, Ertugrul Taciroglu, Yuntian Wang, Yuhang Li
Keywords(s): 3D structures, Adaptive Optics, AI-generated images and content, all-optical diffractive computing, all-optical transformation, analog computing, analog optical computing, Analogue Electronics, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial-intelligent materials, civil engineering, civil infrastructure, civil monitoring, computational imaging, computational imaging task, Construction, deep diffractive network, Diffraction, diffractive design, diffractive image reconstruction, diffractive network, diffractive processor, diffractive surface, digital image reconstruction, electromagnetic spectrum, Electro-Optics, Image Analysis, Image Processing, Image Resolution, image restoration, image signal processing, Imaging, Infrastructure, Lens (Optics), linear optics, Nanostructure, optical processor, optically-guided structural monitoring, Optics, passive light-matter interactions, security imaging, Signal Reconstruction, Structural health monitoring, structural health monitoring (SHM), structure monitoring, Structures
Category(s): Electrical, Electrical > Signal Processing, Electrical > Imaging, Materials, Materials > Construction Materials, Electrical > Visual Computing, Electrical > Computing Hardware, Electrical > Instrumentation, Energy & Environment, Energy & Environment > Energy Efficiency, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Software & Algorithms > Programs
Sulfonyl-purine probes for covalent targeting of lysine and tyrosine in drug discovery
Background A significant portion of the human proteome remains inaccessible to traditional drug discovery approaches, particularly proteins lacking reactive cysteines or well-defined binding pockets. These so-called “undruggable” targets present major challenges for small molecule therapeutics, limiting the development of treatments for...
Published: 12/4/2025   |   Inventor(s): Ku-Lung Hsu, Zhihong Li
Keywords(s):  
Category(s): Life sciences > Therapeutics > Formulation, Life sciences > Research tools > Reagent
Metal organic framework membranes for ion transport and separation
Background Ion-selective separation membranes play a critical role in applications such as water purification, energy storage, and chemical processing. These tech­nologies are essential for tackling global challenges like clean water scarcity, efficient energy utilization, and sustainable industrial processes. Traditional ion separation methods,...
Published: 12/3/2025   |   Inventor(s): Huacheng Zhang, Xingya Li, Huanting Wang, Jun Lu, Anita Hill, Benny Freeman
Keywords(s):  
Category(s): Physical sciences > Materials > Membranes
Hyperbranched Polyglycerol Encapsulated Proteins for Oral Protein Delivery (Case No. 2012-425)
Patent Abstract: Methods for modifying therapeutic agents such as therapeutic biomolecules, such as proteins for improved oral, rectal or transmucosal delivery, as well as compositions made using such methods and methods of administering such compositions to a subject, are disclosed. Specifically, the therapeutic agents are conjugated to hyperbranched...
Published: 12/1/2025   |   Inventor(s): Yunfeng Lu, Juanjuan Du, Jie Li, Yang Liu
Keywords(s):  
Category(s): Platforms > Drug Delivery
Fungal Bioelectronic Thermoreceptor
Executive Summary Traditional electronic temperature sensors such as thermistors and thermocouples offer precision but lack flexibility, durability, and self-healing capabilities. They often fail under mechanical stress and cannot adapt to dynamic environments. Researchers at Michigan State University (MSU) have developed a flexible biohybrid temperature...
Published: 11/24/2025   |   Inventor(s): Jinxing Li, Yulu Cai
Keywords(s): Sensor Technologies
Category(s): Devices
Ultrafast Thin-Film Vapor Deposition Technique
Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...
Published: 11/18/2025   |   Inventor(s): Feng Yan, Lin Li
Keywords(s):  
Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical
Ultra Black and Ultra White Coating on Different Sides of a Wind Turbine Blade to have Additional Energy from Solar
This invention aims to improve the efficiency and power output of wind turbines using additional energy from sunlight. The pressure side of each wind turbine blade is coated ultra black, and the suction side of each wind turbine blade is coated ultra white. When sunlight shines on the turbine, these coatings cause the light to contribute to the rotational...
Published: 11/13/2025   |   Inventor(s): Peiwen Li
Keywords(s):  
Category(s): Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy > Wind, Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy, Technology Classifications > Materials > Coatings
Gene Editing for Head and Neck Cancer Treatment
Application Method for delivering gene-editing therapeutic in head and neck cancers. Key Benefits CRISPR/CAS9-based gene editing mechanism targeting novel disease-modifying gene. Liquid nanoparticle encapsulation permitting in vivo delivery. Market Summary Head and neck cancers (HNC) are the 7th most common global cancer, accounting for 3%...
Published: 11/7/2025   |   Inventor(s): Yong Teng, Yamin Li
Keywords(s): Drug Discovery, Drug Target Identification, Gene Therapy and Editing, Nanoparticle Drug Delivery, Oncology Treatments, Reagents, Biomaterials, and Plasmids
Category(s): TechPub Algolia > Therapeutics
Methods For The Prediction Of Drug Penetration and Exposure In The Human Brain
Description: A novel 9‑compartment physiologically based pharmacokinetic model was developed and fully validated for prediction of heterogeneous drug distribution and exposure in the human central nervous system (CNS) and brain tumors. The 9-compartment model accounts for the general anatomical structure and pathophysiology of the human CNS and brain...
Published: 11/21/2025   |   Inventor(s): Jing Li, Seongho Kim, Charuka Wickramasinghe
Keywords(s):  
Category(s): Technology Category > Life Science, Technology Category > Method, Technology Category > Drug Screening, Technology Category > Drug Delivery
Modifying Angiogenic Sprouting Using Pulsed Electromagnetic Fields (PEMF)
­ A novel method for the treatment of chronic wounds based on amplitude-modulated pulsed electromagnetic fields (PEMFs). Background: Chronic wounds adversely impact the quality of life and health of patients and their families, due to pain, anxiety, loss of function, loss of mobility, depression, shame, and social isolation. Wound healing requires...
Published: 10/29/2025   |   Inventor(s): Linghong Li, Wayne Patton
Keywords(s): angiogenic sprouting, autophagy-lysosomal pathway, cytoplasmic granulation, electromagnetic field, ion cyclotron resonance, sprouting, Technologies
Category(s): Campus > SUNY Potsdam, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
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