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Small molecules that target RNA structures within the CoV genome
​ Chemical structure of the three lead molecules derived from the focused library screen against OC43-infected Vero E6 cell screening (Zafferani et al 2021) Invention Summary: The SARS-CoV-2 pandemic, and the likelihood of future coronavirus pandemics, emphasized the urgent need for development of novel antivirals. Small-molecule chemical probes...
Published: 4/9/2025   |   Inventor(s): Amanda Hargrove, Blanton Tolbert, Gary Brewer, Neeraj Patwardhan, Mei-Ling Li
Keywords(s): Antiviral, Respiratory Disease
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Glanceability in Augmented Reality Systems
THE CHALLENGE All-day wearable augmented reality (AR) devices, particularly smart glasses, will be increasingly available in the near future, revolutionizing the way people live and work. Impediments limiting further adoption are not only related to hardware, but also to insights surrounding presentation and interaction with virtual information. OUR...
Published: 4/9/2025   |   Inventor(s): Doug Bowman, Feiyu Lu, Wallace Santos Lages, Shakiba Davari-Najafabadi, Lorance Lisle, Yuan Li
Keywords(s):  
Category(s): Technology Classifications > Consumer Products
Method for Vascular Regeneration and Wound Treatment
Asset/Technology Type Therapeutic Strategy Description of Invention The invention is a therapeutic approach for modulating cellular trans-differentiation and potentially angiogenesis by modulating O-glcnacylation (GlcNAc) of proteins, to treat various conditions. The inventors used existing small molecules to prove the concept in vitro and in vivo....
Published: 4/2/2025   |   Inventor(s): John Cooke, Li Lai
Keywords(s):  
Category(s): Clinical Area, Clinical Area > Cardiovascular, Research Area > Heart and Vascular, Research Area > Regenerative Medicine, Technology Classifications, Technology Classifications > Other
DNA/RNA Origami Assembly Mediated by Functional Peptides
DNA and RNA nanostructures, e.g., DNA Origami, have great potential in biological applications, including extracellular matrix scaffolds and delivery vehicles for drugs and gene therapies. While folding DNA origami under physiological conditions is plausible, significant challenges and limitations remain. For example, isothermal annealing of DNA origami...
Published: 4/2/2025   |   Inventor(s): Di Liu, Bing Xu, Zhishang Li, Jiaqi Guo
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biological Nanotechnology, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Nucleic Acid/Peptide/Protein Therapies
Advanced Mobile Navigation and Mapping App
­Improves mobile mapping and navigation apps by visualizing distant landmarks that typically fall outside the device display area. Background: Existing mobile map or navigation apps generally provide directions through distance and turn-by-turn instructions – for example, “after 1 mile, turn right on to Lakeview street.” Directions...
Published: 4/1/2025   |   Inventor(s): Rui Li, Jiayan Zhao
Keywords(s): augmented reality, autonomous vehicle, spatial cognition, Technologies, visualization, wayfinding and navigation
Category(s): Campus > University at Albany, Technology Classifications > Electronics, Technology Classifications > Instrumentation, Technology Classifications > Wireless Technologies
Albany Rural Cemetery Explorer and Grave Finder (Apps)
Provides an online tool for exploring the Albany Rural Cemetery, allowing visitors to find graves, view themed tours virtually or on mobile phones in the cemetery with composed biographies of individual graves, and enjoy the cemetery’s natural beauty. Background: Albany Rural Cemetery (ARC), located in Menands, New York, is one of the oldest...
Published: 4/1/2025   |   Inventor(s): Rui Li, Kurt Swartz, Jackson LaSarso, James Billings
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Education and Training, Technology Classifications > Information Technology, Technology Classifications > Social Sciences
Modifying Angiogenic Sprouting Using Pulsed Electromagnetic Fields (PEMF)
­ A novel method for the treatment of chronic wounds based on amplitude-modulated pulsed electromagnetic fields (PEMFs). Background: Chronic wounds adversely impact the quality of life and health of patients and their families, due to pain, anxiety, loss of function, loss of mobility, depression, shame, and social isolation. Wound healing requires...
Published: 4/1/2025   |   Inventor(s): Linghong Li, Wayne Patton
Keywords(s): angiogenic sprouting, autophagy-lysosomal pathway, cytoplasmic granulation, electromagnetic field, ion cyclotron resonance, sprouting, Technologies
Category(s): Campus > SUNY Potsdam, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
Human Trabecular Organ-on-a-Chip Models
3D biomimetic hydrogel models of the trabecular meshwork of the eye, and a bioengineered system for modelling the conventional outflow tract. Background: Models of the trabecular meshwork have largely been 2D up until now, but research has shown that 2D models of the TM behave differently -- sometimes in complete opposition -- to 3D models. A 3D model...
Published: 4/1/2025   |   Inventor(s): Samuel Herberg, Preethi Ganapathy, Haiyan Li
Keywords(s):  
Category(s): Campus > Upstate Medical University, Technology Classifications > Screens and Assays
Methods and Sequences for mRNA and Other HIV Vaccine Development
Unique sequences eliciting broadly neutralizing antibodies (bNAbs) against human immunodeficiency virus (HIV) that could be used to develop effective mRNA-based and other types of HIV vaccine. Problem: Despite decades of research, there is currently no vaccine to prevent HIV infection. A major goal of HIV vaccine programs is to generate bNAbs, which...
Published: 3/31/2025   |   Inventor(s): George Shaw, Edward (Ted) Kreider, Beatrice Hahn, Ashwin Skelly, Hui Li, Drew Weissman
Keywords(s): Bioengineering, HIV/AIDS, Immunology, Infectious Disease, Protein/Peptide (Non-Antibody)
Category(s): Technology Classifications > Vaccines
Tricyclic Inhibitors of Ribosome‐Inhibiting Proteins
​ An image that shows p-stalk binding blockage would lead to the prevention of damage caused by Shiga or Ricin toxins Invention Summary: Shiga Toxin-producing E. coli (STEC) are very common bacteria that can cause infections that lead to approximately 100,000 illnesses, 3,000 hospitalizations, and about 90 deaths annually in the United States....
Published: 3/31/2025   |   Inventor(s): Jacques Roberge, Xiao-Ping Li, Anastasiia Tsymbal, Nilgun Tumer
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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