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Search Results - chen+chen
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DGR-MIL: Diverse Global Representation in Multiple Instance Learning
Histological whole slide image (WSI) processing techniques are critical for identifying and classifying tissues, particularly cancerous tissues. AI-aided methods for analyzing these WSIs have become increasingly important to enhance diagnostic precision and high throughput processing. However, WSIs have gigapixel resolution, leading to computational...
Published: 5/28/2025
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Inventor(s):
Wenhui Zhu
,
Xiwen Chen
,
Peijie Qiu
,
Yalin Wang
,
Aristeidis Sotiras
,
Abolfazl Razi
Keywords(s):
Category(s):
Artificial Intelligence/Machine Learning
,
Computing & Information Technology
,
Imaging
,
Life Science (All LS Techs)
Multi-Object Grasping -- Grasping from Surface of Pile
Advantages: High Efficiency in Cluttered Environments Vision-Guided Dexterity with 6D Pose Estimation Confidence-Driven Grasp Optimization Adaptive to Real-World Variability Scalable for Industrial Automation Summary: Robotic grasping in industries like manufacturing, warehousing, and logistics is still a bottleneck when dealing with dense...
Published: 5/28/2025
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Inventor(s):
Tianze Chen
,
Yu Sun
Keywords(s):
Robotics
Category(s):
Technology Classifications > Engineering > Chemical Engineering
,
Technology Classifications > Engineering > Mechanical Engineering
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Technology Classifications > Engineering > Industrial Engineering
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
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Technology Classifications > Medical > Therapeutics
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Technology Classifications > Medical > Pharmaceuticals
Aeroacoustic Duster
Precision particle removal from a surface with no physical contact using a bounded vortex and peripheral jets providing streamlines Background: Mitigation of dust or particle build up on surfaces is a problem in many industries, especially where the surface being cleaned cannot be damaged, such as optical materials or delicate electronic instruments....
Published: 5/21/2025
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Inventor(s):
Jeffrey Marshall
,
Darren Hitt
,
Di Chen
,
Jun-Ru Wu
,
Nicholas Vachon
Keywords(s):
Category(s):
Technology Classifications > Engineering
Diagnosis of hypertrophic cardiomyopathy and left ventricular hypertrophy using frequency domain analysis of ECG signals
Background Cardiac conditions involving abnormal thickening of the heart muscle, such as hypertrophic cardiomyopathy (HCM) and left ventricular hypertrophy (LVH), present significant diagnostic challenges due to their overlapping symptoms and similar manifestations in standard ECG readings. Existing diagnostic methods—including echocardiograms,...
Published: 5/19/2025
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Inventor(s):
Dongmei Chen
,
Edward Kim
,
Wei Li
Keywords(s):
Category(s):
Computer > Algorithms and software methods > Healthcare
,
Computer > Algorithms and software methods
Chirped Laser Dispersion Spectroscopy Sensitivity Booster
Chirped Laser Dispersion Spectroscopy Sensitivity Booster (Princeton Docket # 16-3267) Inventors: Gerard Wysocki, Genevieve B. Plant, Yifeng Chen Laser-based gas sensing has entered a new era of precision with this innovative technology designed to overcome traditional sensitivity limitations. By integrating a local oscillator channel and advanced...
Published: 5/14/2025
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Inventor(s):
Genevieve Plant
,
Yifeng Chen
,
Gerard Wysocki
Keywords(s):
Category(s):
Mechanical/Electrical Engineering
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 5/13/2025
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Inventor(s):
Ing-Nang Wang
,
Hua Shi
,
Jia Sheng
,
Alan Chen
Keywords(s):
bacteriophage purification
,
phage purification
,
phage therapy
,
RNA aptamer
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Biological Materials
,
Technology Classifications > Biomedical Science and Engineering
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Technology Classifications > Healthcare
,
Technology Classifications > Research Tools and Reagents
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Technology Classifications > Therapeutics and Vaccines
Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium
Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 5/13/2025
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Inventor(s):
Qiang Zhang
,
Huan Chen
Keywords(s):
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications
,
Technology Classifications > Biological Materials
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Healthcare
,
Technology Classifications > Materials and Chemicals
,
Technology Classifications > Research Tools and Reagents
,
Technology Classifications > Therapeutics and Vaccines
Novel Mouse Model for Developing Therapeutic Drugs Against Muscle Atrophy
Mouse model stably overexpressing Ant-1 for muscle atrophy therapy development. Background: Muscle disorders are commonly manifested in mitochondria-induced diseases, which are clinically referred to as mitochondrial myopathies. In classic mitochondrial myopathies, caused by mutations in mitochondrial DNA or in nuclear genes encoding mitochondrial...
Published: 5/13/2025
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Inventor(s):
Xin Jie Chen
,
Xiaowen Wang
Keywords(s):
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Research Tools and Reagents
,
Technology Classifications > Biomedical Science and Engineering
Competency Med Assessment Pro
Invention Summary: Competency Medical Assessment Pro (MAP) is a real‐time online assessment system developed as an innovative solution designed to streamline the feedback process to medical students, focusing on the 13 Entrustable Professional Activities (EPAs) essential for medical school graduation, as outlined by the AAMC (American Association...
Published: 5/9/2025
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Inventor(s):
Archana Pradhan
,
Steven Wen
,
Guangde He
,
Jie Zhao
Keywords(s):
Category(s):
Technology Classifications > Software & Copyright
,
Technology Classifications > Software & Algorithms
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