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Interactive Extended Reality Worlds with JSON Data Generated by Large Language Models
Recent LLM-XR systems mostly drive experiences by generating and compiling code on the fly. In complex scenes with thousands of artifacts and properties, models struggle to pick the right context, inflating token usage and still missing crucial constraints—like keeping cups on tables. Hallucinated or malformed scripts often fail to compile or...
Published: 10/10/2025   |   Inventor(s): Tian Lan, Bin Li, Jiangong Chen
Keywords(s):  
Category(s): Technology Classifications > Computers Electronics & Software > Artificial Intelligence, Technology Classifications > Computers Electronics & Software > Image Processing and Analysis
Mouth Rescue Rinse to Reduce and Regulate Blood Pressure
Contains Inorganic Nitrates and L-arginine to Facilitate Nitric Oxide Production This mouthwash contains inorganic nitrates and L-arginine to facilitate nitric oxide (NO) production, enabling blood pressure reduction and regulation. Primary hypertension affects 34% of U.S. adults 20 years and older. While several factors, including demographic and...
Published: 10/10/2025   |   Inventor(s): Joseph Katz, Lina Cui, Zixin Chen
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Nutraceutical
Dynamic Fluid-Assisted Micro Continuous Liquid Interface Production Platform
Invention Description Functionally graded materials (FGMs) offer the ability to create structures with spatially varying properties, enabling advanced performance in applications such as biomedical devices, soft robotics, and high-performance composites. However, existing multi-material 3D printing systems, such as stereolithography, are often slow...
Published: 10/8/2025   |   Inventor(s): Wenbo Wang, Xiangfan Chen
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Manufacturing/Construction/Mechanical, Medical Devices, Physical Science, Wearable
Machine learning model for real-time prediction of bottom-hole circulating temperature in geothermal wells
Background Drilling high-temperature geothermal wells presents significant technical and economic challenges due to the extreme conditions encountered deep underground. Effective thermal management is crucial to ensure that the bottom-hole circulating temperature (BHCT) remains within the operational limits of downhole tools, which is essential for...
Published: 10/6/2025   |   Inventor(s): Eric van Oort, Dongmei Chen, Pradeepkumar Ashok, Ningyu Wang, Anthony Luu
Keywords(s):  
Category(s): Physical sciences > Energy > Oil & gas > Upstream oil & gas, Physical sciences > Energy > Renewable, green, or transitional energy
A class of anion redox active materials for rechargeable batteries
Background The rapid evolution of battery technologies has ignited a fervent quest for safer, more efficient, and sustainable solutions. As lithium-ion batteries (LIBs) continue to dominate the market, concerns about the availability and cost of lithium resources have spurred interest in alternative battery chemistries. Among the emerging contenders,...
Published: 10/6/2025   |   Inventor(s): Arumugam Manthiram, Jiarui He, Amruth Bhargav
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
Rechargeable battery electrolytes for extreme cycling conditions
Background As the world increasingly relies on portable electronics, electric vehicles, and renewable energy storage, the demand for high-performance, reliable, and durable rechargeable batteries continues to grow. However, current lithium-ion batteries (LIBs) face significant challenges under extreme operating condi­tions, such as subzero temperatures,...
Published: 10/6/2025   |   Inventor(s): Arumugam Manthiram, Zehao Cui, Chen Liu
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
Non-flammable electrolyte mixtures for high-stability alkali-metal batteries
Background As the demand for sustainable energy storage solutions grows during the advancement of portable electronics and electric vehicles, there is a pressing need for enhanced energy storage systems. Alkali-metal batteries are a promising solution for energy storage due to their high energy-density capabilities. However, their widescale adoption...
Published: 10/3/2025   |   Inventor(s): Arumugam Manthiram, Jiarui He, Amruth Bhargav
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
MKK3/MYC Protein-Protein Interaction Inhibitor Overcomes Resistant Non-Small Cell Lung Cancer
Application A therapeutic use for SGI-1027 in the treatment of Osimertinib-resistant non-small cell lung cancer (NSCLC). Key Benefits The MKK3/MYC protein-protein interaction inhibitor SGI-1027 effectively decreases MYC levels in Osimertinib-resistant NSCLC cell lines. The combination of SGI-1027 with Osimertinib offers synergistic benefits over...
Published: 10/3/2025   |   Inventor(s): Andrey Ivanov, Haian Fu, Shi-Yong Sun, Zhen Chen
Keywords(s): Drug Discovery, Oncology Treatments, Protein and Peptide Therapeutics
Category(s): TechPub Algolia > Therapeutics
Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)
Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...
Published: 10/1/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun
Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery
Optical Generative Models (Case No. 2025-067)
Summary: Researchers in the UCLA Department of Electrical and Computer Engineering have developed an optics-based system to rapidly generate synthetic images. Background: Generative AI models that create synthetic images, human-like natural language processing capabilities, and even new protein designs are critical for a diverse array of applications....
Published: 10/1/2025   |   Inventor(s): Aydogan Ozcan, Shiqi Chen
Keywords(s): Adaptive Optics, all-optical diffractive computing, Electro-Optics, Optical Coherence , Optical computing, Optical Generative Models, Optics
Category(s): Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Optics & Photonics, Electrical, Electrical > Signal Processing, Electrical > Imaging, Electrical > Visual Computing
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