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Novel Real Time Scheduler
THE CHALLENGE Scheduling bandwidth for multiple cell phone users is presently accomplished almost on an arbitrary basis using a predefined algorithms developed to maximize throughput. Since the scheduling frames are updated every 1 ms, this approach has made it virtually impossible to allocate bandwidth in a real-time, on-demand basis, to achieve best...
Published: 4/9/2025   |   Inventor(s): Yan Huang, Yiwei Thomas Hou, Yongce Chen
Keywords(s):  
Category(s): Technology Classifications > Communication
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 4/1/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium
Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 4/1/2025   |   Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
IRF4-Engineered T Cells Induce T Cell Function As a Treatment Strategy for Solid Tumors
Asset/Technology Type New Therapeutic Strategy Description of Invention The invention includes compositions and methods of delivering therapeutic anti-tumor T cells by forcing them to overexpress interferon regulatory factor (IRF4) as a treatment for various solid tumors, including but not limited to melanoma, lymphoma, and colon cancer. The inventors...
Published: 4/11/2025   |   Inventor(s): Wenhao Chen, Xian Li
Keywords(s):  
Category(s): Clinical Area > Transplantation, Clinical Area > Cancer, Clinical Area > Metabolic Disease, Inflammation, and Immunology, Research Area > Cancer, Research Area > Immunobiology and Inflammation, Technology Classifications > Therapeutic > Cell and Gene Therapies
Highly Accelerated and High-Resolution T1-Weighted MRI
This invention is for an accelerated, high-resolution T1-weighted magnetic resonance imaging (MRI) via modification of the three-dimensional magnetization-prepared rapid gradient echo (3D MP-RAGE) sequence. Through this modification, optimization is achieved by allowing for faster signal collection and shorter acquisition time with generation of optimal...
Published: 3/24/2025   |   Inventor(s): Silu Han, Nan-kuei Chen
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Neurology
Acoustic Radiation Force Impulse Procedures for Modulating Glial Cells and Neurons in the Central Nervous System
This technology leverages focused ultrasound and Acoustic Radiation Force Impulse (ARFI) techniques to improve brain health by normalizing synaptic activity and enhancing waste clearance in the central nervous system. It provides two non-invasive procedures: one targets astrocytes to modulate synaptic activity, while the other stimulates the glymphatic...
Published: 3/24/2025   |   Inventor(s): Nan-kuei Chen
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Sensors & Controls > Motion & Force, Technology Classifications > Medical Devices > Therapeutic
REV-ERBα Modulators for the Treatment of Autoimmune Disorders
Activates the REV-ERBα Nuclear Receptor to Suppress TH17 Cell Development and TH17-Mediated Autoimmune and Chronic Inflammation These small molecules activate the REV-ERBα nuclear receptor to repress TH17 cell activity and treat autoimmune and chronic inflammatory disorders. TH17 cells are a subset of CD4+ T cells that play key roles in...
Published: 3/13/2025   |   Inventor(s): Laura Solt, Theodore Kamenecka, Yuanjun He, Brett Bookser, Mike Lizarzaburu
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 3/4/2025   |   Inventor(s): Yong Zeng, He Yan
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
A Ventilated Artificial Human Lung Exposure System to Analyze and Test Human Exposures to Inhaled Substances (Case No. 2023-306)
Summary: UCLA researchers in the Department of Medicine and Environmental Health Sciences have developed a ventilated human lung system for laboratory testing of inhaled substances. Background: Measuring the toxicology of inhaled air, aerosols and other substances is challenging due to the complexity of human studies and limitations in existing...
Published: 3/27/2025   |   Inventor(s): Michael Roth, Airi Harui, Yifang Zhu, Haoxuan Chen
Keywords(s): aerosol, Angiogenesis Acute Lung Injury, bioaerosol, cardiopulmonary illness, Cellular Respiration, consumer goods and products, Lung, Lung Pulmonology, non-small cell lung cancer, Preclinical model development, Preclinical surgical innovation, pulmonary arterial pressure (PAP), pulmonary failure, Pulmonary fibrosis, Respiratory & Pulmonary, respiratory failure, right atrial to pulmonary canula, Simulation & Modeling, simulation model, small cell lung cancer
Category(s): Platforms, Platforms > Drug Delivery, Life Science Research Tools, Life Science Research Tools > Research Methods, Therapeutics, Therapeutics > Respiratory And Pulmonary, Mechanical, Mechanical > Sensors
Smart Nanoparticle-Based Cellular Transfection Tool for Therapeutic Development
Utilizes Light-Responsive Nanoparticles to Load Exosomes with Cargo Molecules Precisely and Efficiently, Maximizing Their Ability as Therapeutics This smart nanoparticle-based cellular transfection tool utilizes light-responsive nanoparticles to load therapeutic cargo molecules on demand into extracellular vesicles (EVs), or so-called exosomes, for...
Published: 2/26/2025   |   Inventor(s): Mei He
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
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