Search Results - synthesis

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Process for Practical, Scalable, Commercially-viable Method for the Synthesis of Enantio-enriched Aminoalcohols, Including the Novel Antifungal VT-1129 Used to Treat Cryptococcal Meningitis
This technology relates to the discovery and development of a practical, scalable, and commercially viable method for the synthesis of the novel antifungal VT-1129. Cryptococcal meningitis (CM) is a fungal infection that is particularly prevalent in immune-compromised patients and can be treated by VT-1129. CM has a current estimated patient population...
Published: 7/25/2024   |   Inventor(s): Mark Behnke, Scott David, Douglas Fry, William Hoekstra, Christopher Yates, Asaf Alimardanov
Keywords(s): Acid, Alcohol, Aminoalcohols, Benzenesulfonic, BSA., Co-crystal, Containing, Derivatives, Enantioenriched, Fragment, Including, Listed LPM Nguyen-Antczak as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PROCESS, Synthesis, Tertiary, THOSE, VEXXXX, VT-1129, WMXXXX
Category(s): Application > Consumer Products, TherapeuticArea > Neurology
Use of Modified Peptide Nucleic Acids for Visualizing DNA
The compounds described in this technology may be useful in the development of nucleic acid detection kits for various pathogens. Technologies for genomic detection most commonly use DNA probes to hybridize to target sequences, and require the use of Polymerase Chain Reaction (PCR) to amplify target sequences. Replacing the DNA probe with peptide nucleic...
Published: 7/25/2024   |   Inventor(s): Daniel Appella
Keywords(s): 2, Acid, Acids, Anthrax, APPLICATIONS, Cross-Coupled, Cyclopentan, Detection, Diamine-modified, Gamma-lysine, Modified, Nucleic, Patent Category - Chemistry, PATHOGENS, Peptide, Probes, SARS, Severe acute respiratory syndrome, Synthesis, Trans-1, YXXXXX
Category(s): Collaboration Sought > Collaboration
Sustainable Dehydrocoupling and Hydrofunctionalization Methods for Preparing Aminosilanes, Polysilazane Coatings, and Silicones
Background Silicon nitride, silicon oxynitride, silicon carbonitride, and silicon dioxide films are used to protect the semiconducting regions of microprocessors, memory devices, and solar panels. These coatings are prepared by atomic layer deposition (ALD) or chemical vapor deposition (CVD) using aminosilanes, or by applying perhydropolysilazane solutions....
Published: 2/23/2023   |   Inventor(s): Ryan Trovitch, Anuja Sharma, Thu Thao Nguyen
Keywords(s): Catalysis, Chemicals, Electronics, Fabrication, Pharmaceutical, Polymer, Reagents, Small Molecule, Small Organic Molecules, Synthesis
Category(s): Bioanalytical Assays, Chemistries & Devices, Physical Science, Semiconductors, Materials & Processes
Electroactive Poly(amidoamine) Organic Polymers (EPOP)
The market for point of care test strips demands high quality tests and low production costs without sacrificing sensitivity and specificity. Highly-ordered nanomaterials are being investigated as a viable approach for meeting these demands. Highly-ordered nanomaterials are ideal as they are inexpensive to manufacture and have been shown to produce...
Published: 2/23/2023   |   Inventor(s): Jeffrey LaBelle, Trevor Saxman, Brittney Cardinell
Keywords(s): Battery, Bioanalytical/Sample Reagents, Bio-Technology, Diagnostics, Fuel Cells, Energy, Nanostructure, Polymer, Reagents, Sensors, Synthesis
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Biomaterials, Chemical/Biological Sensors, Diagnostic Assays/Devices, Life Science (All LS Techs)
Substituted Phenols and Benzenes for Pharmaceuticals, Agrochemicals and Synthetic Materials
Technology Description This technology licensing opportunity is for novel phenol and benzene compounds with any number of substituents and complete positional selectivity. Synthesis of the compounds is achieved by a new synthetic method. The method provides a one-step conversion of readily available starting materials to give phenols with complete...
Published: 5/23/2023   |   Inventor(s): Chris Beaudry, Xiaojie Zhang
Keywords(s): agrochemical, benzenes, chemistry, medicinal, organic, pharmaceuticals, phenols, polymer, substituted, synthesis
Category(s): Agricultural, Chemical, Therapeutics
Ratiometric optical dual oxygen and pH sensor with three emission colors
The efficiency of biofuel production depends on the photosynthetic activity of microbes; to maximize their growth it is necessary to continually monitor the environmental conditions. Traditional monitoring methods (such as using electrodes to measure CO2 consumption and/or O2 generation) are typically time- and labor-intensive, have low throughput,...
Published: 2/23/2023   |   Inventor(s): Yanqing Tian, Weiwen Zhang, Deirdre Meldrum, Hongguang Lu, Yuguang Jin, Mark Holl
Keywords(s): Agriculture and Animal Science, Bio-Technology, Cancer, Detection, Fluorescence, Hydrogels, Materials, Probe, Sensors, Synthesis
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Life Science (All LS Techs)
Catalyst for Manufacturing Photoconducting Materials
Links Metal Ions in a Polymer Chain to Improve the Efficiency and Stability of Photo and Electro Responsive Materials This catalyst enhances the efficiency and stability of photovoltaic solar cells and other light-reactive materials. Photovoltaic cells, which convert photons from light into voltage, form the foundation of solar energy technologies....
Published: 6/27/2021   |   Inventor(s): Adam Veige, Trevor Del Castillo, Leslie Murray, Andrew Powers, Xi Yang
Keywords(s): click, Electronic, hsuigen cyclo edition, Materials, Metallopolymer, photoresponsive, synthesis
Category(s): Technology Classifications > Engineering > Chemical
Photosynthetic Production of 3-Hydroxybutyrate from Carbon Dioxide
The market interest in bioproduction of chemicals and polymers is steadily growing, driven by sustainability concerns and increashttp://azte.technologypublisher.com/files/sites/ncs-m12-182,-m14-208l,-m14-232l.pdfed environmental awareness. However, most production technologies rely on petroleum or food crops as feedstocks. In the coming decades, materials...
Published: 2/23/2023   |   Inventor(s): Bo Wang, Weiwen Zhang, Deirdre Meldrum, David Nielsen
Keywords(s): Algae, Microalgae, Cyanobacteria, Biofuels Production, Bioplastic and Biopolymers, Bio-Technology, Cell Metabolism, Chemicals, Environmental, Food, Grain, Nutrition, Metabolic, Photosynthesis, Solar Energy, Synthesis
Category(s): Alternative Energy/Biofuels/Bioplastics/Algae, Life Science (All LS Techs), Vectors/Constructs/Plasmids
Low complexity Out-of-Order Issue Logic using Static circuits
Instruction-level parallelism (ILP) is a measure of how many of the operations in a computer program can be performed simultaneously. Superscalar techniques based on extracting instruction-level parallelism have been a major contribution to high performance microprocessor design throughout the last decade. The number of instructions executed...
Published: 2/23/2023   |   Inventor(s): Lawrence Clark, Siddhesh Mhambrey, Satendra Maurya
Keywords(s): Logic, Synthesis
Category(s): Semiconductor Devices, Semiconductors, Materials & Processes