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Causal Physics-Informed Neural Networks Training System For Physical Simulation
A computer-based training system improves physics-informed neural networks (PINNs) training by weighted residual loss terms to account for physical causality. Problem: Conventional PINNs can struggle with dynamical systems that show multi-scale, chaotic, or turbulent behavior. Existing formulations may fail to respect the spatio-temporal causal structure...
Published: 7/28/2026
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Updated: 7/28/2026
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Inventor(s):
Paris Perdikaris
,
Sifan Wang
Keywords(s):
Artificial Intelligence (AI) & Machine Learning
,
Software
Category(s):
Technology Classifications > Computer Information Systems
,
Technology Classifications > Imaging
Radiation-Resilience Layered Structure for Direct Energy Conversion Devices (Radwich)
Invention Description Reliable power generation in extreme or remote environments is challenging, especially where conventional energy sources or battery replacement are impractical. Devices exposed to radiation or harsh operating conditions often experience material degradation that reduces efficiency and operational lifespan over time. Existing compact...
Published: 7/28/2026
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Updated: 7/28/2026
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Inventor(s):
Mariana Bertoni
,
David Fenning
,
Chaitanya Deo
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Energy & Power
,
Physical Science
Peptide Therapeutic for Promoting Tumor Cell DNA Damage and Natural Killer Cell-Mediated Metastatic Surveillance
This invention is a cell-penetrating peptide therapeutic that blocks nuclear epidermal growth factor receptor (nEGFR) localization to induce tumor regression and natural killer (NK) cell-mediated metastatic surveillance of triple-negative breast cancer (TNBC). Mouse model studies demonstrated that inhibiting nEGFR trafficking induces NK cell surveillance,...
Published: 7/28/2026
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Updated: 7/28/2026
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Inventor(s):
Joyce Schroeder
,
Ryan Hecksel
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Oncology
,
Technology Classifications > Life Sciences > Therapeutics
Chalcone-Ferroptosis Inducer hybrids as dual mechanism anti-cancer agents
Project ID: TECH2026-09 Formidable success in cancer patient treatment has been achieved by mono therapy, employing a single potent drug designed for a specific therapeutic target. Mono therapy is simple, practical, and has high patient compliance. With multiple drug prescriptions, patient compliance drops. However, cancer easily circumvents...
Published: 7/28/2026
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Updated: 7/28/2026
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Inventor(s):
Liyanaaratchige Tillekeratne
,
William Taylor
,
Samkeliso Dlamini
Keywords(s):
Category(s):
Oncology
Cavity-Resonant Air-Breathing Microwave Plasma Jet
Atmospheric-pressure plasma sources are used in plasma-assisted processing, biomedical treatment and sterilization, surface modification, environmental remediation, agricultural treatment, propulsion, photonics, and plasma-assisted acceleration. Many conventional sources rely on inductively coupled plasma, dielectric-barrier discharge, electrode-based...
Published: 7/28/2026
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Updated: 7/28/2026
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Inventor(s):
Abbas Semnani
,
Kushagra Singhal
,
Tahir Azam
Keywords(s):
Category(s):
Electrical
Liquid Biopsy Detection of TF-Ag-α-Positive Cancer-Associated Exosomes
A liquid biopsy assay detecting TF-Ag-α–positive tumor-derived exosomes for cancer screening, early detection and treatment monitoring. Background: Cancer diagnostics are rapidly evolving as early detection and treatment monitoring are critical to improving patient outcomes. Traditional methods such as imaging and tissue biopsies are...
Published: 7/28/2026
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Updated: 7/28/2026
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Inventor(s):
Yun Wu
,
Grace Dy
,
Kate Rittenhouse-Olson
Keywords(s):
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Diagnostics
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Technology Classifications > Engineering
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Technology Classifications > Medical Devices
,
Technology Classifications > Sensors
Carpal Arch Space Augmentation (CASA) with FUFA
This invention is a radioulnar wrist compression device designed to treat carpal tunnel syndrome (CTS) involving a biomechanical approach to augment the carpal arch area. This device involves mechanisms of wrist compression for carpal arch space augmentation to alleviate median nerve compression and restore impaired neurophysiological and biomechanical...
Published: 7/27/2026
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Updated: 7/27/2026
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Inventor(s):
Zong-Ming Li
Keywords(s):
Category(s):
Technology Classifications > Medical Devices > Therapeutic
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Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone
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Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Sensors & Controls
A Method for Fast Beam Scanning and Device Discovery in 5G Millimeter Wave Systems
Title: A Method for Fast Beam Scanning and Device Discovery in 5G Millimeter Wave SystemsInvention: This technology, known as FastLink, is a technique to quickly and accurately discover devices on a cellular network using highly directional beams and a unique binary search algorithm. This device is designed for use in 5G systems to provide faster initial...
Published: 7/27/2026
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Updated: 7/27/2026
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Inventor(s):
Marwan Krunz
,
Irmak Aykin
,
Berk Akgun
Keywords(s):
Category(s):
Technology Classifications > Engineering & Physical Sciences > Communications & Networking > Wireless
Luminescent biosensor for detection of nucleotide sequences, small molecules, and proteins at the point-of-care
This technology is a modular, luminescent biosensor that rapidly detects DNA, RNA, small molecules, and proteins at the point of care, using a visible color change measurable by a smartphone, enabling fast, sensitive, and equipment-free diagnostics. Background: Molecular diagnostics is a rapidly evolving field that plays a critical role in the detection...
Published: 7/27/2026
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Updated: 7/27/2026
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Inventor(s):
Harsimranjit Sekhon
,
Stewart Loh
Keywords(s):
bio/chemical sensors
,
bioluminescence
,
biomarker diagnostics
,
biosensor
,
nanoluciferase
,
Technologies
,
therapeutic drug monitoring
,
Virus Detection
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Diagnostics
MobilePTX: AI-based Analytical Method for Limited POC Ultrasound Imaging data
PAGE TITLE Overview PAGE SUMMARY This technology is a novel artificial intelligence (AI) system designed for point-of-care ultrasound (POCUS) imaging, utilizing a sparse coding framework to enhance the extraction and interpretation of ultrasound features. This explainable AI methodology can help create diagnostic tools that are accurate, transparent,...
Published: 7/27/2026
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Updated: 7/27/2026
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Inventor(s):
Christopher MacLellan
,
Rosina Weber
,
Edward Kim
,
Darryl Hannan
,
Steven Nesbit
,
Qiao Zhang
,
Glen Smith
,
Alberto Goffi
,
Vincent Chan
,
Ximing Wen
Keywords(s):
Category(s):
Computing, AI, Software, Cybersecurity & Analytics
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