Search Results - reagents

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Molecular Detection and Viral-Load Quantification for HIV-1 Groups M, N and O, and Simian Immunodeficiency Virus-cpz (SIVcpz)
This invention provides materials, methods, and assays for detecting HIV-1 groups M and O and optionally HIV-1 group N and simian immunodeficiency virus-cpz (SIV-cpz). Specific nucleic acid primers for hybridization, amplification, and detection of HIV-1 are also provided for. The nucleic acid amplification assays can detect small concentrations of...
Published: 5/9/2025   |   Inventor(s): Danuta Pieniazek, Renu Lal
Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4AXX, DA4XXX, DAXXXX, Detection, DXXXXX, Groups, HIV-1, M, Methods, Molecular, N, O, OID-NCHHSTP-DHPSE, REAGENTS, VLXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX, YEXXXX
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Diagnostics, Application > Occupational Safety and Health, TherapeuticArea > Ophthalmology, Application > Therapeutics, Application > Research Materials, TherapeuticArea > Cardiology, TherapeuticArea > Oncology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease
Nucleic Acid Amplification Technique for Rapid Diagnostic Analysis
CDC researchers developed a simple target-specific isothermal nucleic acid amplification technique, termed Genome Exponential Amplification Reaction (GEAR). The method employs a set of four primers (two inner and two outer). The outer primer pair targets three specific nucleic acid sequences at a constant 60°C, while the inner pair of primers accelerates...
Published: 4/24/2025   |   Inventor(s): Prithiviraj Jothikumar, Vincent Hill, Jothikumar Narayanan
Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC4XXX, AC5XXX, Acids, ACXXXX, amplification, AMPLIFYING, AXXXXX, DA1XXX, DA2XXX, DA3XXX, DA4XXX, DA5XXX, DAXXXX, DXXXXX, Exponential, Gear, Genome, Isothermal, Methods, Nucleic, REACTION, REAGENTS, UBXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics, TherapeuticArea > Rare/Neglected Diseases
Development of Reagents to Examine the Expression and Function of CYP2J Subfamily P450s
Cytochrome P450s catalyze the metabolism of a wide range of exogenous compounds, including drugs, industrial chemicals, environmental pollutants, and carcinogens. The 2C family of cytochrome P450 metabolizes an extensive number of drugs which include tolbutamide, S-Warfarin, mephenytoin, diazepam and taxol. The inventors cloned the cDNAs for several...
Published: 10/28/2024   |   Inventor(s): Darryl Zeldin, Jennifer Bradbury
Keywords(s): CYP2J, Development, Examine, Expression, FUNCTION, Listed LPM Contreras as of 4/15/2015, P450s, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, R1XXXX, REAGENTS, RXXXXX, SUBFAMILY
Category(s): Collaboration Sought > Collaboration, Application > Research Materials
Sustainable Dehydrocoupling and Hydrofunctionalization Methods for Preparing Aminosilanes, Polysilazane Coatings, and Silicones
Background Silicon nitride, silicon oxynitride, silicon carbonitride, and silicon dioxide films are used to protect the semiconducting regions of microprocessors, memory devices, and solar panels. These coatings are prepared by atomic layer deposition (ALD) or chemical vapor deposition (CVD) using aminosilanes, or by applying perhydropolysilazane solutions....
Published: 5/2/2025   |   Inventor(s): Ryan Trovitch, Anuja Sharma, Thu Thao Nguyen
Keywords(s): Catalysis, Chemicals, Electronics, Fabrication, Pharmaceutical, Polymer, Reagents, Small Molecule, Small Organic Molecules, Synthesis
Category(s): Bioanalytical Assays, Chemistries & Devices, Physical Science, Semiconductors, Materials & Processes
Electroactive Poly(amidoamine) Organic Polymers (EPOP)
The market for point of care test strips demands high quality tests and low production costs without sacrificing sensitivity and specificity. Highly-ordered nanomaterials are being investigated as a viable approach for meeting these demands. Highly-ordered nanomaterials are ideal as they are inexpensive to manufacture and have been shown to produce...
Published: 2/13/2025   |   Inventor(s): Jeffrey LaBelle, Trevor Saxman, Brittney Cardinell
Keywords(s): Battery, Bioanalytical/Sample Reagents, Bio-Technology, Diagnostics, Fuel Cells, Energy, Nanostructure, Polymer, Reagents, Sensors, Synthesis
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Biomaterials, Chemical/Biological Sensors, Diagnostic Assays/Devices, Life Science (All LS Techs)