Frequency Domain Diffuse Correlation Spectroscopy

Advantages:

Robust simultaneous quantitative measurement of tissue blood flow and absorption, ensuring reliability and enabling easy cross-subject comparisons for versatility.
Single source source-detector separation measurement, reducing the size of the optical probe significantly for portability.
Simplifies electronics by eliminating the need for phase-sensitive detection, enhancing instrument efficiency and design.

Summary:

Current techniques combining Diffuse Optical Spectroscopy (DOS) and Diffuse Correlation Spectroscopy (DCS) face challenges of increased instrument size, higher costs, and fidelity issues. The logistics of handling additional fiber optics limit applicability, and differences in measurement geometry between DOS and DCS instruments result in systematic errors, impacting measurement accuracy.

Frequency Domain Diffuse Correlation Spectroscopy (FD-DCS) offers a unified tissue measurement model, addressing limitations of current techniques. Requiring only one source-detector separation reduces the optical probe size by up to three times. FD-DCS eliminates the need for phase-sensitive detection, simplifying electronics and enhancing measurement robustness for easy cross-subject comparison. With speed advantages over existing hybrid approaches, FD-DCS improves diffuse optical device portability, versatility, and reliability.