NU 2023-078
INVENTORS Cheng Sun* Hao Zhang* Alex Huang Raymond Fang Pengpeng Zhang Tingwei Zhang
SHORT DESCRIPTION A robotic visible-light optical coherence tomography (OCT) system designed for comprehensive imaging of the anterior segment of the eye, introducing novel computational alignment algorithms and a lightweight OCT sample arm for enhanced imaging capabilities.
BACKGROUND We developed a robotic visible-light OCT system targeting the anterior segment of the eye, marking a pioneering application of robotic OCT for imaging the cornea and limbus. This system features a compact, lightweight OCT sample arm and leverages computational algorithms to align the robotic arm's tool reference frame with the eye's reference frame, addressing the need for detailed, non-invasive eye examinations.
ABSTRACT This technology comprises a robotic OCT system for the anterior segment of the eye, utilizing visible light for detailed imaging. It represents a significant advancement in ocular imaging, offering a novel approach to aligning the imaging system with the eye's anatomy for enhanced resolution and image quality. The system's design facilitates a range of applications in ocular health, from surgery planning to treatment monitoring, through its innovative use of robotic technology and computational algorithms.
APPLICATIONS
360-degree imaging of the conventional outflow pathway for microinvasive glaucoma surgery
Monitoring of the palisades of Vogt for dry eye disease treatment
Evaluation of surgical and pharmacological treatment effectiveness on the anterior eye segment
Detailed imaging for a better understanding of segmental outflow patterns in glaucoma
High-resolution tear film layer imaging
Enhanced lateral resolution in the anterior eye segment through multiple angle scanning
Custom 3D eye modeling and printing for ocular device design
3D conformal scanning of the cornea for precise structural feature imaging
ADVANTAGES
Improved anisotropic lateral resolution through multiple scanning angles
Enhanced visualization of critical structures like Schlemm's Canal and palisades of Vogt
Ability to capture images without requiring large-angle eye fixation by participants
Reduced acquisition times for anterior segment scans
Design ensures normal incidence to anatomy, increasing signal-to-noise ratio
Full 360-degree imaging capability for comprehensive outflow pathway exploration
IP STATUS US Patent Pending