Search Results - hector+mendez-gomez

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Patient-specific prostate cancer progression prediction model to inform personalized treatment
Problem Prostate cancer is a significant health problem worldwide, and there is a vital need for accurate predictive models of disease progression to aid in effective treatment planning. Current models are largely statistical, based on a population of patients, and neglect the patient’s unique attributes. There is a significant need for more...
Published: 2/12/2024   |   Inventor(s): Thomas Hughes, Hector Gomez, Guillermo Lorenzo
Keywords(s):  
Category(s): Life sciences > Medical technology > TechBio (software innovation in healthcare) > Bioinformatics, Life sciences > Therapeutics
Nanoparticle RNA Vaccine to Treat Gliomas
Encodes for Specific Antigens to Promote Anti-Tumor Immunity This cancer vaccine activates antigen-presenting cells and induces anti-tumor immune system activity for the treatment of diffuse intrinsic pontine gliomas (DIPG). DIPG tumors originate in the pons, an area of the brainstem controlling vital body functions such as breathing and heart rate....
Published: 7/30/2021   |   Inventor(s): Elias Sayour, James McGuiness, Hector Mendez-Gomez, Duane Mitchell
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Nanoparticle RNA Vaccine That Targets Slow-Cycling, Treatment-Resistant Cancer
Activates T-Cell Recognition of Tumor-Initiating Stem Cells in Mouse Model of Glioma This nanoparticle vaccine targets the slow-cycling, treatment-resistant, cancer stem cells to improve efficiency of anti-cancer drugs, thereby improving disease prognosis. Despite major developments in the field of anti-cancer therapies, tumor recurrence and metastasis...
Published: 2/13/2024   |   Inventor(s): Elias Sayour, Loic Deleyrolle, Hector Mendez-Gomez, Sadeem Qdaisat, Duane Mitchell
Keywords(s): Cancer, cancer stem cells, Immunotherapy, Nanoparticles, Vaccine development
Category(s): Technology Classifications > Human Health Care > Therapeutics
Receptor-Ligand Combination for Specific Drug Delivery to the Brain
Molecule Crosses the Blood-Cerebrospinal Fluid Barrier to Deliver Therapy into Targeted CellsThis engineered receptor-ligand combination targets and crosses the brain barriers of mammals to deliver drugs and therapeutics to the brain. About 12 percent of all deaths worldwide are caused by neurological disorders such as Alzheimer’s, Parkinson’s...
Published: 12/20/2021   |   Inventor(s): Hector Mendez-Gomez, Nicholas Muzyczka
Keywords(s): Blood-brain barrier, brain delivery, brain-specific drug delivery, Gene Therapy, receptor-mediated transcytosis
Category(s): Technology Classifications > Human Health Care > Drug Delivery, Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Research Tools > Therapeutics